A continuous assay for DNA cleavage: the application of "break lights" to enediynes, iron-dependent agents, and nucleases (Q35567329)

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2 November 2019

title

A continuous assay for DNA cleavage: the application of "break lights" to enediynes, iron-dependent agents, and nucleases (English)

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2 November 2019

1

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2 November 2019

James R Prudent

2

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2 November 2019

Jon S Thorson

5

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2 November 2019

author name string

D J Marshall

3

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2 November 2019

M Ruppen

4

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2 November 2019

language of work or name

English

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publication date

1 December 2000

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Proceedings of the National Academy of Sciences of the United States of America

2 November 2019

published in

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2 November 2019

volume

97

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2 November 2019

issue

25

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2 November 2019

page(s)

13537-13542

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Using molecular beacons as a sensitive fluorescence assay for enzymatic cleavage of single-stranded DNA.

2 November 2019

cites work

1 reference

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Intracellular ribozyme-catalyzed trans-cleavage of RNA monitored by fluorescence resonance energy transfer

12 July 2018

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Monoclonal antibodies to the myeloid stem cells: therapeutic implications of CMA-676, a humanized anti-CD33 antibody calicheamicin conjugate

12 July 2018

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Bleomycin: new perspectives on the mechanism of action

12 July 2018

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Selective ablation of acute myeloid leukemia using antibody-targeted chemotherapy: a phase I study of an anti-CD33 calicheamicin immunoconjugate

12 July 2018

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Molecular beacons: probes that fluoresce upon hybridization

12 July 2018

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Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: high throughput screening for enzyme activity

12 July 2018

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Real-time enzyme kinetics monitored by dual-color fluorescence cross-correlation spectroscopy

12 July 2018

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Synthetic and biological catalysts in chemical synthesis: how to assess practical utility

12 July 2018

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Fluorescence assays for DNA cleavage

12 July 2018

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Solution structure of the calicheamicin gamma 1I-DNA complex

12 July 2018

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12 July 2018

The enediyne antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17611

Chemistry and biology of natural and designed enediynes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17611

Real time kinetics of restriction endonuclease cleavage monitored by fluorescence resonance energy transfer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17611

A fluorometric assay for DNA cleavage reactions characterized with BamHI restriction endonuclease

12 July 2018

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Use of isotope-dilution phenomenon to advantage in the determination of kinetic constants Km and Kcat for BamHI restriction endonuclease: an empirical and iterative approach

12 July 2018

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Interactions of the EcoRV restriction endonuclease with fluorescent oligodeoxynucleotides

12 July 2018

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Reaction kinetics of some important site-specific endonucleases

12 July 2018

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Physical and kinetic properties of the site specific endonuclease Bam HI from Bacillus amylolique-faciens

12 July 2018

1 reference

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Methidiumpropyl-EDTA-Fe(II) and DNase I footprinting report different small molecule binding site sizes on DNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=17611

Binding of non-substrate nucleotides to a restriction endonuclease: a model for the interaction of Bam HI with its recognition sequence

12 July 2018

1 reference

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Stimulation of iron(II) bleomycin activity by phosphate-containing compounds

12 July 2018

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Bleomycin-induced strand-scission of DNA. Mechanism of deoxyribose cleavage

12 July 2018

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12 December 2020

The DNA cleavage mechanism of iron-bleomycin. Kinetic resolution of strand scission from base propenal release

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12 December 2020

Calicheamicin gamma 1I: an antitumor antibiotic that cleaves double-stranded DNA site specifically

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12 December 2020

The enzymes of the BamH I restriction-modification system

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12 December 2020

Calicheamicin gamma 1I and DNA: molecular recognition process responsible for site-specificity

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12 December 2020

Hydroxyl radical footprinting

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12 December 2020

Multicolor molecular beacons for allele discrimination

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12 December 2020

Identifiers

DOI

10.1073/PNAS.240460997

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2 November 2019

0 references

1 reference

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2 November 2019

PubMed publication ID

11095715

1 reference