Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen. (Q35569826)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

title

Polyoma middle tumor antigen interacts with SHC protein via the NPTY (Asn-Pro-Thr-Tyr) motif in middle tumor antigen (English)

1 reference

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23 October 2019

2

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23 October 2019

author name string

K S Campbell

1

1 reference

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23 October 2019

B Burke

3

1 reference

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23 October 2019

W Su

4

1 reference

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23 October 2019

K R Auger

5

1 reference

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23 October 2019

B J Druker

6

1 reference

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23 October 2019

B S Schaffhausen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

T M Roberts

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

D C Pallas

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

language of work or name

English

0 references

publication date

1 July 1994

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 October 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

volume

91

1 reference

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23 October 2019

issue

14

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23 October 2019

page(s)

6344-6348

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

23 October 2019

cites work

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

12 July 2018

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Pulling springs to tune transduction: adaptation by hair cells

12 July 2018

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Shc products are substrates of erbB-2 kinase

12 July 2018

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Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor

12 July 2018

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SH2 domains recognize specific phosphopeptide sequences

12 July 2018

1 reference

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Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigen.

12 July 2018

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Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides

12 July 2018

1 reference

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Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen

12 July 2018

1 reference

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Polyomavirus: an overview of its unique properties

12 July 2018

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Polyoma virus transforming protein associates with the product of the c-src cellular gene

12 July 2018

1 reference

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DNA sequences of polyoma virus early deletion mutants

12 July 2018

1 reference

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Identification of DNA sequence changes leading to loss of transforming ability in polyoma virus

12 July 2018

1 reference

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Polyoma middle-sized T antigen can be phosphorylated on tyrosine at multiple sites in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Inhibition of NIH 3T3 cell proliferation by a mutant ras protein with preferential affinity for GDP.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Association of phosphatidylinositol kinase activity with polyoma middle-T competent for transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Cellular proteins that associate with the middle and small T antigens of polyomavirus

12 July 2018

1 reference

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Recombinant retroviruses that transduce middle T antigen cDNAs derived from polyomavirus mutants: separation of focus formation and soft-agar growth in transformation assays and correlations with kinase activities in vitro.

12 July 2018

1 reference

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Oncogenes, growth factors, and signal transduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Association of p60fyn with middle tumor antigen in murine polyomavirus-transformed rat cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Structural and functional modification of pp60c-src associated with polyoma middle tumor antigen from infected or transformed cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Site-directed mutagenesis of polyomavirus middle-T antigen sequences encoding tyrosine 315 and tyrosine 250.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Phosphatidylinositol metabolism and polyoma-mediated transformation

12 July 2018

1 reference

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In vitro mutagenesis of the putative membrane-binding domain of polyomavirus middle-T antigen

12 July 2018

1 reference

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A completely transformation-defective point mutant of polyomavirus middle T antigen which retains full associated phosphatidylinositol kinase activity

12 July 2018

1 reference

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NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Oncogenes and signal transduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Cellular ras gene activity is required for full neoplastic transformation by polyomavirus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

SH2 and SH3 domains: from structure to function

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Reversion of middle T antigen-transformed Rat-2 cells by Krev-1: implications for the role of p21c-ras in polyomavirus-mediated transformation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Interactions of polyomavirus middle T with the SH2 domains of the pp85 subunit of phosphatidylinositol-3-kinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Polyoma virus middle T antigen-pp60c-src complex associates with purified phosphatidylinositol 3-kinase in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Polyomavirus middle T-antigen NPTY mutants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Phosphorylation of polyoma T antigens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

New classes of viable deletion mutants in the early region of polyoma virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Construction and analysis of viable deletion mutants of polyoma virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=44198

Association of the polyomavirus middle-T antigen with c-yes protein

12 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8022784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An 81 kd protein complexed with middle T antigen and pp60c-src: a possible phosphatidylinositol kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8022784

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.91.14.6344

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8022784%20AND%20SRC:MED&resulttype=core&format=json

23 October 2019

1 reference