A uroguanylin-GUCY2C endocrine axis regulates feeding in mice (Q35572696)

8 August 2017

A uroguanylin-GUCY2C endocrine axis regulates feeding in mice (English)

1 reference

8 August 2017

Michael S Magee

7

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Adam E. Snook

object named as

Adam E Snook

3

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Scott A. Waldman

object named as

Scott A Waldman

10

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author name string

Michael A Valentino

1

1 reference

8 August 2017

Jieru E Lin

2

1 reference

8 August 2017

Peng Li

4

1 reference

8 August 2017

Gilbert W Kim

5

1 reference

8 August 2017

Glen Marszalowicz

6

1 reference

8 August 2017

Terry Hyslop

8

1 reference

8 August 2017

Stephanie Schulz

9

1 reference

8 August 2017

language of work or name

English

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publication date

25 August 2011

1 reference

Journal of Clinical Investigation

8 August 2017

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8 August 2017

121

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8 August 2017

3578-3588

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8 August 2017

9

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The rat kidney contains high levels of prouroguanylin (the uroguanylin precursor) but does not express GC-C (the enteric uroguanylin receptor).

8 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Central and peripheral molecular targets for antiobesity pharmacotherapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Recent advances in understanding leptin signaling and leptin resistance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Differential susceptibility to obesity between male, female and ovariectomized female mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Circulating prouroguanylin is processed to its active natriuretic form exclusively within the renal tubules

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Uroguanylin, an intestinal natriuretic peptide, is delivered to the kidney as an unprocessed propeptide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Insulin, cGMP, and TGF-beta signals regulate food intake and quiescence in C. elegans: a model for satiety

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Natural variation in food acquisition mediated via a Drosophila cGMP-dependent protein kinase

27 July 2018

1 reference

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The paracrine hormone hypothesis of colorectal cancer.

27 July 2018

1 reference

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Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Overweight and obesity: prevalence, consequences, and causes of a growing public health problem

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

The gut and energy balance: visceral allies in the obesity wars

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Uroguanylin knockout mice have increased blood pressure and impaired natriuretic response to enteral NaCl load

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

A simple method for the isolation and purification of total lipides from animal tissues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Cholecystokinin-A receptors are involved in food intake suppression in rats after intake of all fats and carbohydrates tested

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Regulation of nitric oxide-responsive recombinant soluble guanylyl cyclase by calcium.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Effect of leptin deficiency on metabolic rate in ob/ob mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Comparison of effects of uroguanylin, guanylin, and Escherichia coli heat-stable enterotoxin STa in mouse intestine and kidney: evidence that uroguanylin is an intestinal natriuretic hormone.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Gene expression profiles in normal and cancer cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Regulation of intestinal uroguanylin/guanylin receptor-mediated responses by mucosal acidity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Guanylyl cyclase C is a selective marker for metastatic colorectal tumors in human extraintestinal tissues

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

The guanylin/STa receptor is expressed in crypts and apical epithelium throughout the mouse intestine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

A role for glucagon-like peptide-1 in the central regulation of feeding

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Weight-reducing effects of the plasma protein encoded by the obese gene

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

The development of obesity in genetically diabetic-obese (db/db) mice pair-fed with lean siblings. The importance of thermoregulatory thermogenesis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Guanylyl cyclase is a heat-stable enterotoxin receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Guanylin: an endogenous activator of intestinal guanylate cyclase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Increased lipid absorption and transport in the small intestine of zucker obese rats

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Effect of 5 days linaclotide on transit and bowel function in females with constipation-predominant irritable bowel syndrome

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Critical role for peptide YY in protein-mediated satiation and body-weight regulation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

The proximal convoluted tubule is a target for the uroguanylin-regulated natriuretic response.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Cellular effects of guanylin and uroguanylin

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Uroguanylin and guanylin regulate transport of mouse cortical collecting duct independent of guanylate cyclase C.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Oxyntomodulin and glucagon-like peptide-1 differentially regulate murine food intake and energy expenditure.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Peripheral oxyntomodulin reduces food intake and body weight gain in rats.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

The world health report 2002 - reducing risks, promoting healthy life

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Guanylin and uroguanylin induce natriuresis in mice lacking guanylyl cyclase-C receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Acute effects of PYY3-36 on food intake and hypothalamic neuropeptide expression in the mouse.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Prouroguanylin and proguanylin: purification from colon, structure, and modulation of bioactivity by proteases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Escherichia coli heat-stable toxin receptors in human colonic tumors.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3223926

Gene expression in colorectal cancer

26 September 2018

1 reference

12 December 2020

Expression of guanylin is downregulated in mouse and human intestinal adenomas

1 reference

12 December 2020

Changes in urinary levels and renal expression of uroguanylin on low or high salt diets in rats

1 reference

12 December 2020

Identification of 10-kDa proguanylin as a major guanylin molecule in human intestine and plasma and its increase in renal insufficiency

1 reference

12 December 2020

Intestinal lipid absorption is not affected in CD36 deficient mice

1 reference

12 December 2020

Guanosine 3',5'-cyclic monophosphate-dependent protein kinase II mediates heat-stable enterotoxin-provoked chloride secretion in rat intestine

1 reference

12 December 2020

Guanylin mRNA expression in human intestine and colorectal adenocarcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI57925

1 reference

release_2msv35cd3zdcfgezomksoukelq

8 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/2msv35cd3zdcfgezomksoukelq

24 November 2022

mapped directly with Wikidata item

PMCID

3223926

1 reference

8 August 2017

1 reference