Structural mechanism of integrin inactivation by filamin. (Q35582169)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849143%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Structural mechanism of integrin inactivation by filamin (English)

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4 March 2020

7

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4 March 2020

author name string

Jianmin Liu

1

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4 March 2020

Mitali Das

2

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4 March 2020

Jun Yang

3

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4 March 2020

Sujay Subbayya Ithychanda

4

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4 March 2020

Valentin P Yakubenko

5

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4 March 2020

Edward F Plow

6

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4 March 2020

publication date

6 April 2015

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Nature Structural & Molecular Biology

4 March 2020

published in

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4 March 2020

volume

22

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4 March 2020

issue

5

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4 March 2020

page(s)

383-389

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SnapShot: talin and the modular nature of the integrin adhesome

4 March 2020

cites work

1 reference

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Filamin-A regulates neutrophil uropod retraction through RhoA during chemotaxis

12 July 2018

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Three-dimensional reconstruction of intact human integrin IIb 3: new implications for activation-dependent ligand binding

12 July 2018

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Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity

12 July 2018

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Structural studies on full-length talin1 reveal a compact auto-inhibited dimer: implications for talin activation

12 July 2018

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Integrin inactivators: balancing cellular functions in vitro and in vivo

12 July 2018

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A novel membrane-dependent on/off switch mechanism of talin FERM domain at sites of cell adhesion

12 July 2018

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Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling

12 July 2018

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Migfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils

12 July 2018

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SHARPIN is an endogenous inhibitor of β1-integrin activation

12 July 2018

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Proteomic signature of thrombin-activated platelets after in vivo nitric oxide-donor treatment: coordinated inhibition of signaling (phosphatidylinositol 3-kinase-γ, 14-3-3ζ, and growth factor receptor-bound protein 2) and cytoskeleton protein [...]

12 July 2018

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Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion

12 July 2018

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Identification and characterization of multiple similar ligand-binding repeats in filamin: implication on filamin-mediated receptor clustering and cross-talk

12 July 2018

1 reference

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Structure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation

12 July 2018

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The structure of an integrin/talin complex reveals the basis of inside-out signal transduction.

12 July 2018

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The structure of a receptor with two associating transmembrane domains on the cell surface: integrin alphaIIbbeta3.

12 July 2018

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The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

12 July 2018

1 reference

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Migfilin, a molecular switch in regulation of integrin activation

12 July 2018

1 reference

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Structural basis for the autoinhibition of talin in regulating integrin activation

12 July 2018

1 reference

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Beta2 integrin phosphorylation on Thr758 acts as a molecular switch to regulate 14-3-3 and filamin binding

12 July 2018

1 reference

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Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

12 July 2018

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Structural basis of integrin activation by talin

12 July 2018

1 reference

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The molecular basis of filamin binding to integrins and competition with talin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4424056

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

12 July 2018

1 reference

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The Xplor-NIH NMR molecular structure determination package

12 July 2018

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Integrins: bidirectional, allosteric signaling machines

12 July 2018

1 reference

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A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face

12 July 2018

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Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration

12 July 2018

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Filamins as integrators of cell mechanics and signalling

12 July 2018

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Protein backbone angle restraints from searching a database for chemical shift and sequence homology

12 July 2018

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12 July 2018

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Autoantibodies against the platelet glycoprotein IIb/IIIa complex in patients with chronic ITP

12 July 2018

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Activation-dependent redistribution of the adhesion plaque protein, talin, in intact human platelets

12 July 2018

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12 July 2018

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Loss of migfilin expression has no overt consequences on murine development and homeostasis.

26 September 2018

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26 September 2018

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Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins

26 September 2018

1 reference

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Docking of protein-protein complexes on the basis of highly ambiguous intermolecular distance restraints derived from 1H/15N chemical shift mapping and backbone 15N-1H residual dipolar couplings using conjoined rigid body/torsion angle dynamics.

26 September 2018

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

26 September 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNSMB.2999

21 January 2018

Identifiers

DOI

10.1038/NSMB.2999

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849143%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849143%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

25849143

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849143%20AND%20SRC:MED&resulttype=core&format=json