Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population (Q35588251)

9 August 2017

Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population (English)

1 reference

9 August 2017

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26

Loic Le Marchand

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Stacey Gabriel

35

Stacey Gabriel

1 reference

Juan Carlos Fernandez-Lopez

9 August 2017

Juan C Fernandez-Lopez

14

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Amy L Williams

Amy L Williams

12

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Humberto García-Ortiz

Humberto García-Ortiz

7

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Josep Maria Mercader

Josep M Mercader

6

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Pål R Njølstad

50

Pål R Njølstad

1 reference

9 August 2017

43

Michael Boehnke

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9 August 2017

Christopher A. Haiman

46

Christopher A Haiman

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24

E Henderson

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9 August 2017

49

David Altshuler

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3

Ingvild Aukrust

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9 August 2017

Lise Bjørkhaug Gundersen

4

Lise Bjørkhaug

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41

Graeme I Bell

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45

Lorena Orozco

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25

Lynne R Wilkens

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9 August 2017

34

Timothy Fennell

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9 August 2017

52

Daniel G MacArthur

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Carlos Alberto Aguilar Salinas

9 August 2017

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Carlos A Aguilar-Salinas

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9 August 2017

Olimpia Arellano Campos

27

Olimpia Arellano-Campos

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9 August 2017

37

Craig L Hanis

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9 August 2017

38

Donna M Lehman

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9 August 2017

Christopher P. Jenkinson

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Christopher P Jenkinson

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9 August 2017

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Hanna E Abboud

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11

Jason Flannick

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9 August 2017

Federico Centeno-Cruz

17

Federico Centeno-Cruz

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9 August 2017

21

Emilio J Córdova

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Angelica Martinez-Hernandez

9 August 2017

15

Angélica Martínez-Hernández

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9 August 2017

18

Elvia Mendoza-Caamal

1 reference

Cristina Revilla-Monsalve

9 August 2017

19

Cristina Revilla-Monsalve

1 reference

Francisco Xavier Soberón Mainero

9 August 2017

22

Xavier Soberón

1 reference

9 August 2017

2

Karol Estrada

1 reference

9 August 2017

Alicia Huerta-Chagoya

8

Alicia Huerta-Chagoya

1 reference

9 August 2017

Hortensia Moreno-Macías

9

Hortensia Moreno-Macías

1 reference

9 August 2017

20

Sergio Islas-Andrade

1 reference

María E González-Villalpando

9 August 2017

23

María E González-Villalpando

1 reference

9 August 2017

Maribel Rodriguez-Torres

29

Maribel Rodríguez-Torres

1 reference

9 August 2017

33

Suzanne B R Jacobs

1 reference

Clicerio González-Villalpando

9 August 2017

44

Clicerio González-Villalpando

1 reference

9 August 2017

SIGMA Type 2 Diabetes Consortium

1

1 reference

9 August 2017

Noël P Burtt

5

1 reference

9 August 2017

Geoffrey Walford

10

1 reference

9 August 2017

María J Gómez-Vázquez

13

1 reference

9 August 2017

Silvia Jiménez-Morales

16

1 reference

9 August 2017

Maria L Ordóñez-Sánchez

28

1 reference

9 August 2017

Rosario Rodríguez-Guillén

30

1 reference

9 August 2017

Laura Riba

31

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9 August 2017

Laeya A Najmi

32

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9 August 2017

Pierre Fontanillas

36

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9 August 2017

Maria L Cortes

42

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9 August 2017

Teresa Tusié-Luna

47

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9 August 2017

Jose C Florez

51

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9 August 2017

language of work or name

English

0 references

publication date

1 June 2014

1 reference

The Journal of the American Medical Association

9 August 2017

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9 August 2017

311

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9 August 2017

22

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9 August 2017

2305-2314

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Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

9 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Searching for missing heritability: designing rare variant association studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Genome-wide association study identifies three novel loci for type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

SUMOylation of pancreatic glucokinase regulates its cellular stability and activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

An integrated map of genetic variation from 1,092 human genomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Optimal tests for rare variant effects in sequencing association studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Evolution and functional impact of rare coding variation from deep sequencing of human exomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Analysis of case-control association studies with known risk variants

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Diabetes is more lethal in Mexicans and Mexican-Americans compared to Non-Hispanic whites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

A framework for variation discovery and genotyping using next-generation DNA sequencing data

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Role of molecular genetics in transforming diagnosis of diabetes mellitus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Double heterozygous mutations involving both HNF1A/MODY3 and HNF4A/MODY1 genes: a case report

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Prevalence and distribution of type 2 diabetes mellitus in Mexican adult population: a probabilistic survey

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Variance component model to account for sample structure in genome-wide association studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Genetic mapping in human disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

The prevalence of the metabolic syndrome did not increase in Mexico City between 1990-1992 and 1997-1999 despite more central obesity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Genetic cause of hyperglycaemia and response to treatment in diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Hepatocyte nuclear factor 1 alpha (HNF-1 alpha) mutations in maturity-onset diabetes of the young

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

A multiethnic cohort in Hawaii and Los Angeles: baseline characteristics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Mutations in the hepatocyte nuclear factor-1 alpha gene (MODY3) are not a major cause of early-onset non-insulin-dependent (type 2) diabetes mellitus in Japanese.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Diabetes among Mexican Americans in Starr County, Texas

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

A distal dimerization domain is essential for DNA-binding by the atypical HNF1 homeodomain

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

HNF1, a homeoprotein member of the hepatic transcription regulatory network

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Comprehensive molecular analysis of Japanese patients with pediatric-onset MODY-type diabetes mellitus.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Prevalence of monogenic diabetes in young adults: a community-based, cross-sectional study in Oxfordshire, UK.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

A genetic diagnosis of HNF1A diabetes alters treatment and improves glycaemic control in the majority of insulin-treated patients.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Prevalence of diabetes and impaired fasting glucose in adults in the U.S. population: National Health And Nutrition Examination Survey 1999-2002.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Scanning HNF-1 alpha gene mutation in Chinese early-onset and/or multiplex diabetes pedigrees

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

MODY in Iceland is associated with mutations in HNF-1alpha and a novel mutation in NeuroD1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Hyperexcitability to sulphonylurea in MODY3.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Maturity-onset diabetes of the young (MODY): how many cases are we missing?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Prevalence ofHNF1A(MODY3) mutations in a Norwegian population (the HUNT2 Study)

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

Evaluation of Common Variants in the Six Known Maturity-Onset Diabetes of the Young (MODY) Genes for Association With Type 2 Diabetes

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4425850

MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X)

15 November 2018

1 reference

12 December 2020

High frequency of mutations in the HNF-1alpha gene in non-obese patients with diabetes of youth in Japanese and identification of a case of digenic inheritance

1 reference

12 December 2020

Hepatocyte nuclear factor-1 alpha gene mutations and diabetes in Norway

1 reference

12 December 2020

Geography of diabetes mellitus mortality in Mexico: an epidemiologic transition analysis

1 reference

12 December 2020

The inheritance of liability to diseases with variable age of onset, with particular reference to diabetes mellitus

1 reference

12 December 2020

Maturity-onset diabetes of the young (MODY) at least ten times more common in Europe than previously assumed?

1 reference

12 December 2020

The hepatic nuclear factor-1alpha G319S variant is associated with early-onset type 2 diabetes in Canadian Oji-Cree

1 reference

12 December 2020

The type and the position of HNF1A mutation modulate age at diagnosis of diabetes in patients with maturity-onset diabetes of the young (MODY)-3

1 reference

12 December 2020

Identifiers

DOI

10.1001/JAMA.2014.6511

1 reference

9 August 2017

1 reference

9 August 2017

1 reference