Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability. (Q35589664)

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scientific article published on 18 February 2011

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English	Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability.	scientific article published on 18 February 2011

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scholarly article

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22 January 2020

Effects of di(n-butyl) phthalate exposure on foetal rat germ-cell number and differentiation: identification of age-specific windows of vulnerability (English)

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22 January 2020

Richard M Sharpe

4

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22 January 2020

author name string

M S Jobling

1

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22 January 2020

G R Hutchison

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22 January 2020

S van den Driesche

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22 January 2020

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18 February 2011

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22 January 2020

International Journal of Andrology

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22 January 2020

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22 January 2020

e386-96

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22 January 2020

5 Pt 2

1 reference

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Xenografting of human fetal testis tissue: a new approach to study fetal testis development and germ cell differentiation.

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Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

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Phthalates impair germ cell number in the mouse fetal testis by an androgen- and estrogen-independent mechanism

1 reference

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Time- and dose-related effects of di-(2-ethylhexyl) phthalate and its main metabolites on the function of the rat fetal testis in vitro

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Gonocytes, the forgotten cells of the germ cell lineage

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Dose-dependent effects on cell proliferation, seminiferous tubules, and male germ cells in the fetal rat testis following exposure to di(n-butyl) phthalate

1 reference

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Phthalates impair germ cell development in the human fetal testis in vitro without change in testosterone production.

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Mechanisms of action of phthalate esters, individually and in combination, to induce abnormal reproductive development in male laboratory rats

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Germ cell differentiation in the marmoset (Callithrix jacchus) during fetal and neonatal life closely parallels that in the human.

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Testicular dysgenesis syndrome: mechanistic insights and potential new downstream effects

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From gonocytes to testicular cancer: the role of impaired gonadal development

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Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation

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Developmental model for the pathogenesis of testicular carcinoma in situ: genetic and environmental aspects

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Decrease in anogenital distance among male infants with prenatal phthalate exposure

1 reference

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Exposure in utero to di(n-butyl) phthalate alters the vimentin cytoskeleton of fetal rat Sertoli cells and disrupts Sertoli cell-gonocyte contact

1 reference

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Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000

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Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.

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The plasticizer diethylhexyl phthalate induces malformations by decreasing fetal testosterone synthesis during sexual differentiation in the male rat

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Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation

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Comparative effects of neonatal exposure of male rats to potent and weak (environmental) estrogens on spermatogenesis at puberty and the relationship to adult testis size and fertility: evidence for stimulatory effects of low estrogen levels.

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Urinary and amniotic fluid levels of phthalate monoesters in rats after the oral administration of di(2-ethylhexyl) phthalate and di-n-butyl phthalate

1 reference

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Glucocorticoids amplify dibutyl phthalate-induced disruption of testosterone production and male reproductive development

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mRNA expression analysis and the molecular basis of neonatal testis defects in Dmrt1 mutant mice

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Human 'testicular dysgenesis syndrome': a possible model using in-utero exposure of the rat to dibutyl phthalate

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A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner

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Sertoli cell development and function in an animal model of testicular dysgenesis syndrome

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The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

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Abnormal Leydig Cell aggregation in the fetal testis of rats exposed to di (n-butyl) phthalate and its possible role in testicular dysgenesis

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Fetal testosterone insufficiency and abnormal proliferation of Leydig cells and gonocytes in rats exposed to di(n-butyl) phthalate

1 reference

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21 January 2018

Relationship between androgen action in the "male programming window," fetal sertoli cell number, and adult testis size in the rat.

1 reference

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21 January 2018

Detection of phthalate metabolites in human amniotic fluid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2605.2010.01140.X

21 January 2018

Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects

1 reference

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Pathogenesis of male reproductive tract lesions from gestation through adulthood following in utero exposure to Di(n-butyl) phthalate

1 reference

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1 reference

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21 January 2018

Dose-dependent alterations in androgen-regulated male reproductive development in rats exposed to Di(n-butyl) phthalate during late gestation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21332505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and long-term effects of in utero exposure of rats to di(n-butyl) phthalate on testicular germ cell development and proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21332505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fetal mouse phthalate exposure shows that Gonocyte multinucleation is not associated with decreased testicular testosterone

1 reference

https://pubmed.ncbi.nlm.nih.gov/21332505

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2605.2010.01140.X

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Europe PubMed Central

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22 January 2020

1 reference

Europe PubMed Central

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22 January 2020

1 reference

Europe PubMed Central

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22 January 2020

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