STAT3-Activating Cytokines: A Therapeutic Opportunity for Inflammatory Bowel Disease? (Q35589806)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

review article

2 references

12 September 2020

STAT3-Activating Cytokines: A Therapeutic Opportunity for Inflammatory Bowel Disease? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json

inflammatory bowel diseases

2 March 2020

main subject

5 references

21 March 2019

20 November 2019

28 November 2019

22 December 2019

12 September 2020

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20 November 2019

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28 November 2019

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22 December 2019

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12 September 2020

3

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2 March 2020

author name string

Paul M Nguyen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

Tracy L Putoczki

series ordinal

2

1 reference

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2 March 2020

publication date

11 March 2015

1 reference

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Journal of Interferon and Cytokine Research

2 March 2020

1 May 2015

1 reference

12 September 2020

6 references

21 March 2019

20 November 2019

28 November 2019

22 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

12 September 2020

35

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2 March 2020

issue

5

1 reference

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2 March 2020

page(s)

340-350

1 reference

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Creative Commons Attribution-NonCommercial

2 March 2020

copyright license

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22 December 2019

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on focus list of Wikimedia project

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12 July 2018

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12 July 2018

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12 July 2018

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STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Expression of interleukin (IL)-11 receptor by the human endometrium in vivo and effects of IL-11, IL-6 and LIF on the production of MMP and cytokines by human endometrial cells in vitro

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Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10.

12 July 2018

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Cutting edge: immune cells as sources and targets of the IL-10 family members?

12 July 2018

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Cutting edge: STAT activation by IL-19, IL-20 and mda-7 through IL-20 receptor complexes of two types

12 July 2018

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Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity

12 July 2018

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Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22

12 July 2018

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Dendritic cells express tight junction proteins and penetrate gut epithelial monolayers to sample bacteria

12 July 2018

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Interleukin-11 receptor expression in primary ovarian carcinomas

12 July 2018

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Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

12 July 2018

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Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiri

12 July 2018

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Chimeric cytokine receptor can transduce expansion signals in interleukin 6 receptor alpha (IL-6Ralpha)-, IL-11Ralpha-, and gp130-low to -negative primitive hematopoietic progenitors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Identification and functional characterization of a second chain of the interleukin-10 receptor complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Interleukin-11: review of molecular, cell biology, and clinical use.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Interleukin-10-deficient mice develop chronic enterocolitis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Circulating antiinflammatory cytokine IL-10 in patients with inflammatory bowel disease (IBD).

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

The protective role of interleukin-11 against neutron radiation injury in mouse intestines via MEK/ERK and PI3K/Akt dependent pathways.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

High incidence of inflammatory bowel disease in Australia: a prospective population-based Australian incidence study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Genetic factors in chronic inflammation: single nucleotide polymorphisms in the STAT-JAK pathway, susceptibility to DNA damage and Crohn's disease in a New Zealand population.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

The role of cytokine gene polymorphisms in determining disease susceptibility and phenotype in inflammatory bowel disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Induced somatic inactivation of STAT3 in mice triggers the development of a fulminant form of enterocolitis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Randomized, controlled trial of recombinant human interleukin-11 in patients with active Crohn's disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Protection by recombinant human interleukin-11 against experimental TNB-induced colitis in rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Interleukin‐11 protects the clonogenic stem cells in murine small‐intestinal crypts from impairment of their reproductive capacity by radiation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Blockade of interleukin 6 trans signaling suppresses T-cell resistanceagainst apoptosis in chronic intestinal inflammation: Evidence in Crohn diseaseand experimental colitis in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426323

Colonic gene expression patterns of mucin Muc2 knockout mice reveal various phases in colitis development

15 November 2018

1 reference

12 December 2020

Serum biomarkers in a mouse model of bacterial-induced inflammatory bowel disease

1 reference

12 December 2020

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

1 reference

12 December 2020

Is interleukin-6 important in inflammatory bowel disease?

1 reference

12 December 2020

The polymorphism at position –174 of the IL-6 gene is not associated with inflammatory bowel disease

1 reference

12 December 2020

Interleukin-11 modulates Th1/Th2 cytokine production from activated CD4+ T cells

1 reference

12 December 2020

1 reference

12 December 2020

Interleukin-11 prevents apoptosis and accelerates recovery of small intestinal mucosa in mice treated with combined chemotherapy and radiation

1 reference

12 December 2020

Interleukin-6 and soluble interleukin-6 receptor in the colonic mucosa of inflammatory bowel disease

1 reference

12 December 2020

Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts

1 reference

12 December 2020

Interleukin-11 attenuates nephrotoxic nephritis in Wistar Kyoto rats

1 reference

12 December 2020

A polymorphism in the IL11 gene is associated with ulcerative colitis

1 reference

12 December 2020

Effect of interleukin-11 on ameliorating intestinal damage after methotrexate treatment of breast cancer in rats

1 reference

12 December 2020

Pharmacogenomic analysis of rhIL-11 treatment in the HLA-B27 rat model of inflammatory bowel disease

1 reference

12 December 2020

Constitutive STAT3 Activation in Intestinal T Cells from Patients with Crohn's Disease

1 reference

12 December 2020

Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1089/JIR.2014.0225

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

25760898

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25760898%20AND%20SRC:MED&resulttype=core&format=json