Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process. (Q35592271)

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18 January 2020

title

Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process (English)

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18 January 2020

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6

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18 January 2020

author name string

Min-Soo Kim

1

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18 January 2020

Jeong-Soo Kim

2

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18 January 2020

Hee Jun Park

3

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18 January 2020

Won Kyung Cho

4

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18 January 2020

Kwang-Ho Cha

5

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18 January 2020

language of work or name

English

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publication date

24 November 2011

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International Journal of Nanomedicine

18 January 2020

published in

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18 January 2020

volume

6

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18 January 2020

page(s)

2997-3009

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Creative Commons Attribution-NonCommercial 3.0 Unported

18 January 2020

copyright license

start time

1 November 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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New insights into drug absorption: studies with sirolimus

12 July 2018

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Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate

12 July 2018

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The mechanisms of drug release from solid dispersions in water-soluble polymers

12 July 2018

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Solubilization of rapamycin

12 July 2018

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Improving drug solubility for oral delivery using solid dispersions

12 July 2018

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Solid dispersion of poorly water-soluble drugs: early promises, subsequent problems, and recent breakthroughs

12 July 2018

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Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle

12 July 2018

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Enhancement of wettability and dissolution properties of cilostazol using the supercritical antisolvent process: effect of various additives

12 July 2018

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Effect of polymer type on the dissolution profile of amorphous solid dispersions containing felodipine

26 September 2018

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Preparation, characterization and in vivo evaluation of amorphous atorvastatin calcium nanoparticles using supercritical antisolvent (SAS) process

26 September 2018

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Preparation and characterization of simvastatin/hydroxypropyl-beta-cyclodextrin inclusion complex using supercritical antisolvent (SAS) process.

26 September 2018

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Controlled release of sirolimus from a multilayered PLGA stent matrix

26 September 2018

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Cefuroxime axetil solid dispersions prepared using solution enhanced dispersion by supercritical fluids

26 September 2018

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Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process.

26 September 2018

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Liposomal formulations of tacrolimus and rapamycin increase graft survival and fiber outgrowth of dopaminergic grafts

26 September 2018

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CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam

26 September 2018

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26 September 2018

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Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion

26 September 2018

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Metabolism and transport of the macrolide immunosuppressant sirolimus in the small intestine.

26 September 2018

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26 September 2018

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26 September 2018

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12 December 2020

Structural identification of three metabolites and a degradation product of the macrolide immunosuppressant sirolimus (rapamycin) by electrospray-MS/MS after incubation with human liver microsomes

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12 December 2020

Rapamune® (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression

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12 December 2020

Evaluation of rapamycin chemical stability in volatile-organic solvents by HPLC

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12 December 2020

Formulation of sirolimus eye drops and corneal permeation studies

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12 December 2020

An investigation into the dissolution properties of celecoxib melt extrudates: understanding the role of polymer type and concentration in stabilizing supersaturated drug concentrations

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12 December 2020

Identifiers

DOI

10.2147/IJN.S26546

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22162657%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

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18 January 2020

PubMed publication ID

22162657

1 reference