Dimerization of G-protein-coupled receptors: roles in signal transduction (Q35592680)

9 August 2017

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title

Dimerization of G-protein-coupled receptors: roles in signal transduction (English)

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G protein-coupled receptor

9 August 2017

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author name string

Mei Bai

series ordinal

1

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9 August 2017

1 February 2004

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9 August 2017

12

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inferred from page(s)

published in

Cellular Signalling

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9 August 2017

16

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9 August 2017

2

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9 August 2017

175-186

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Seven-transmembrane receptors

9 August 2017

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7 January 2021

Molecular tinkering of G protein-coupled receptors: an evolutionary success

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Conversion of a gonadotropin-releasing hormone antagonist to an agonist

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7 January 2021

Quantitative assessment of beta 1- and beta 2-adrenergic receptor homo- and heterodimerization by bioluminescence resonance energy transfer

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7 January 2021

Glycan-dependent and -independent association of vesicular stomatitis virus G protein with calnexin

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7 January 2021

Detection of beta 2-adrenergic receptor dimerization in living cells using bioluminescence resonance energy transfer (BRET)

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7 January 2021

Biochemical and biophysical demonstration of GPCR oligomerization in mammalian cells

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7 January 2021

Functional rescue of a constitutively desensitized beta2AR through receptor dimerization.

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7 January 2021

Dopamine D2 receptor dimers and receptor-blocking peptides

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7 January 2021

Dopamine D2 receptor dimers in human and rat brain

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7 January 2021

Inhibition of cell surface expression by mutant receptors demonstrates that D2 dopamine receptors exist as oligomers in the cell

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7 January 2021

Expression of dopamine D3 receptor dimers and tetramers in brain and in transfected cells

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7 January 2021

The splice variant D3nf reduces ligand binding to the D3 dopamine receptor: evidence for heterooligomerization

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7 January 2021

Dimerization of the delta opioid receptor: implication for a role in receptor internalization

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7 January 2021

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7 January 2021

G-protein-coupled receptor heterodimerization modulates receptor function

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7 January 2021

Homo- and hetero-oligomeric interactions between G-protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): hetero-oligomers between receptor subtypes form more efficiently than between

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7 January 2021

Oligomer formation of histamine H2 receptors expressed in Sf9 and COS7 cells

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7 January 2021

Identification and molecular characterization of m3 muscarinic receptor dimers.

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7 January 2021

Serotonin 5-HT1B and 5-HT1D receptors form homodimers when expressed alone and heterodimers when co-expressed

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7 January 2021

Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin receptors in living cells by bioluminescence resonance energy transfer

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7 January 2021

The chemokine monocyte chemoattractant protein-1 induces functional responses through dimerization of its receptor CCR2

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7 January 2021

HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization.

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7 January 2021

Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

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7 January 2021

Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies

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7 January 2021

Mechanism of transdominant inhibition of CCR5-mediated HIV-1 infection by ccr5delta32.

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7 January 2021

Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers

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7 January 2021

Involvement of the amino terminus of the B(2) receptor in agonist-induced receptor dimerization.

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7 January 2021

Truncated V2 vasopressin receptors as negative regulators of wild-type V2 receptor function

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7 January 2021

Constitutive and agonist-dependent homo-oligomerization of the thyrotropin-releasing hormone receptor. Detection in living cells using bioluminescence resonance energy transfer

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7 January 2021

Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.

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7 January 2021

Synthesis and characterization of bivalent peptide ligands targeted to G-protein-coupled receptors

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7 January 2021

Biological actions of monoclonal luteinizing hormone/human chorionic gonadotropin receptor antibodies

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7 January 2021

Ig-hepta, a novel member of the G protein-coupled hepta-helical receptor (GPCR) family that has immunoglobulin-like repeats in a long N-terminal extracellular domain and defines a new subfamily of GPCRs

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7 January 2021

Measurement of changes in fluorescence resonance energy transfer between gonadotropin-releasing hormone receptors in response to agonists

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7 January 2021

Gonadotropin-releasing hormone receptor microaggregation. Rate monitored by fluorescence resonance energy transfer

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7 January 2021

Potency enhancement of a GnRH agonist: GnRH-receptor microaggregation stimulates gonadotropin release.

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7 January 2021

Structural basis of glutamate recognition by a dimeric metabotropic glutamate receptor

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7 January 2021

Characterization of the dimerization of metabotropic glutamate receptors using an N-terminal truncation of mGluR1alpha

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7 January 2021

Metabotropic glutamate receptor 5 is a disulfide-linked dimer

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7 January 2021

Dimerization of the extracellular calcium-sensing receptor (CaR) on the cell surface of CaR-transfected HEK293 cells.

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7 January 2021

Probing intermolecular protein-protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET).

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7 January 2021

Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function

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7 January 2021

G-protein-coupled receptors function as oligomers in vivo

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7 January 2021

Homodimerization and heterodimerization of S1P/EDG sphingosine-1-phosphate receptors

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7 January 2021

Dimerization: an emerging concept for G protein-coupled receptor ontogeny and function

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7 January 2021

Inhibition of Gonadotropin-Releasing Hormone Receptor Signaling by Expression of a Splice Variant of the Human Receptor

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7 January 2021

The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation

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7 January 2021

The probable arrangement of the helices in G protein-coupled receptors.

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7 January 2021

Dimerization and domain swapping in G-protein-coupled receptors: a computational study

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7 January 2021

The extracellular N-terminal domain and transmembrane domains 1 and 2 mediate oligomerization of a yeast G protein-coupled receptor

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7 January 2021

Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca(2+) receptor critical for dimerization. Implications for function of monomeric Ca(2+) receptor

1 reference

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7 January 2021

The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions

1 reference

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7 January 2021

GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2.

1 reference

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7 January 2021

GABA(B)-receptor subtypes assemble into functional heteromeric complexes.

1 reference

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7 January 2021

Heterodimerization is required for the formation of a functional GABA(B) receptor

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7 January 2021

Mammalian sweet taste receptors

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7 January 2021

An amino-acid taste receptor

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7 January 2021

D2/D3 dopamine receptor heterodimers exhibit unique functional properties

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7 January 2021

Oligomerization of mu- and delta-opioid receptors. Generation of novel functional properties

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7 January 2021

Homo- and heterodimerization of somatostatin receptor subtypes. Inactivation of sst(3) receptor function by heterodimerization with sst(2A).

1 reference

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7 January 2021

Beta 1/beta 2-adrenergic receptor heterodimerization regulates beta 2-adrenergic receptor internalization and ERK signaling efficacy

1 reference

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7 January 2021

Homo- and hetero-oligomerization of thyrotropin-releasing hormone (TRH) receptor subtypes. Differential regulation of beta-arrestins 1 and 2

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7 January 2021

Chemokine control of HIV-1 infection

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7 January 2021

Chemokine receptor homo- or heterodimerization activates distinct signaling pathways

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7 January 2021

Heterodimerization of somatostatin and opioid receptors cross-modulates phosphorylation, internalization, and desensitization

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7 January 2021

AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration

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7 January 2021

Increased AT(1) receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness

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7 January 2021

Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity

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Oligomerization of opioid receptors with beta 2-adrenergic receptors: a role in trafficking and mitogen-activated protein kinase activation

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7 January 2021

Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function.

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7 January 2021

Coaggregation, cointernalization, and codesensitization of adenosine A2A receptors and dopamine D2 receptors

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7 January 2021

Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes

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7 January 2021

Heteromeric association creates a P2Y-like adenosine receptor

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7 January 2021

Agonist-promoted heteromeric oligomerization between adenosine A(1) and P2Y(1) receptors in living cells.

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7 January 2021

Heterodimerization of calcium sensing receptors with metabotropic glutamate receptors in neurons

1 reference

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7 January 2021

Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function

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7 January 2021

C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors.

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7 January 2021

PAR3 is a cofactor for PAR4 activation by thrombin

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A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely

1 reference

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7 January 2021

A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

1 reference

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7 January 2021

10.1016/S0898-6568(03)00128-1

Identifiers

DOI

1 reference

9 August 2017

1 reference

PubMed ID

14636888