First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin. (Q35597655)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15951546%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin (English)

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12 January 2020

0 references

1

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12 January 2020

Nathan V Subramaniam

series ordinal

4

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12 January 2020

author name string

L Summerville

series ordinal

2

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12 January 2020

P E Lusby

series ordinal

3

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12 January 2020

language of work or name

English

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publication date

1 July 2005

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12 January 2020

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12 January 2020

volume

54

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12 January 2020

issue

7

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12 January 2020

page(s)

980-986

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Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

12 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Hemochromatosis due to mutations in transferrin receptor 2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Hepcidin, a urinary antimicrobial peptide synthesized in the liver

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

LEAP-1, a novel highly disulfide-bonded human peptide, exhibits antimicrobial activity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

The C282Y mutation causing hereditary hemochromatosis does not produce a null allele

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Hepcidin is decreased in TFR2 hemochromatosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Inactivation of the murine Transferrin Receptor 2 gene using the Cre recombinase: loxP system.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

An Hfe-dependent pathway mediates hyposideremia in response to lipopolysaccharide-induced inflammation in mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Functional differences between hepcidin 1 and 2 in transgenic mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1774629

Prohepcidin localises to the Golgi compartment and secretory pathway in hepatocytes

26 September 2018

1 reference

12 December 2020

Decreased liver hepcidin expression in the Hfe knockout mouse

1 reference

12 December 2020

Non-HFE hemochromatosis

1 reference

12 December 2020

Increased hepcidin expression and hypoferraemia associated with an acute phase response are not affected by inactivation of HFE

1 reference

12 December 2020

A simple technique for measuring storage iron concentrations in formalinised liver samples

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.2004.062018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15951546%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15951546%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference