Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination (Q35600299)

9 August 2017

Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination (English)

1 reference

9 August 2017

1 reference

Benjamin A. H. Jensen

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Karen N Nielsen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

Jan Pravsgaard Christensen

12 June 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Allan Randrup Thomsen

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Peter Johannes Holst

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Maria Abildgaard Steffensen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

1 reference

15 July 2014

1 reference

9 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

volume

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

page(s)

2107-2117

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

The availability of a functional tumor targeting T-cell repertoire determines the anti-tumor efficiency of combination therapy with anti-CTLA-4 and anti-4-1BB antibodies

12 June 2020

cites work

1 reference

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Th cells promote CTL survival and memory via acquired pMHC-I and endogenous IL-2 and CD40L signaling and by modulating apoptosis-controlling pathways

12 July 2018

1 reference

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Trial watch: DNA vaccines for cancer therapy

12 July 2018

1 reference

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Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment

12 July 2018

1 reference

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Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

The 20th anniversary of interleukin-2 therapy: bimodal role explaining longstanding random induction of complete clinical responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Vaccine vectors derived from a large collection of simian adenoviruses induce potent cellular immunity across multiple species

12 July 2018

1 reference

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The role of CD80/CD86 in generation and maintenance of functional virus-specific CD8+ T cells in mice infected with lymphocytic choriomeningitis virus

12 July 2018

1 reference

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Immunotherapy for melanoma: current status and perspectives

12 July 2018

1 reference

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Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Distinct roles for IL-2 and IL-15 in the differentiation and survival of CD8+ effector and memory T cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

In vivo expansion of activated naive CD8+ T cells and NK cells driven by complexes of IL-2 and anti-IL-2 monoclonal antibody as novel approach of cancer immunotherapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

One-pot, mix-and-read peptide-MHC tetramers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

The biology of interleukin-2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Interleukin 2: from immunostimulation to immunoregulation and back again

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Immunosuppressive strategies that are mediated by tumor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Treatment of an immortalized APC cell line with both cytokines and LPS ensures effective T-cell activation in vitro

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Interleukin-2 receptor common gamma-chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: selective induction of anti-apoptotic (bcl-2, bcl-xL) but not pro-apoptotic (bax, bcl-xS) gene expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

An efficient and flexible system for construction of adenovirus vectors with insertions or deletions in early regions 1 and 3.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Interleukin-2: inception, impact, and implications

12 July 2018

1 reference

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Long term culture of tumour-specific cytotoxic T cells

12 July 2018

1 reference

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Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice

12 July 2018

1 reference

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Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

26 September 2018

1 reference

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Cutting edge: CD4+ T cell-derived IL-2 is essential for help-dependent primary CD8+ T cell responses.

26 September 2018

1 reference

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Differential role of IL-2R signaling for CD8+ T cell responses in acute and chronic viral infections.

26 September 2018

1 reference

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Selective delivery of augmented IL-2 receptor signals to responding CD8+ T cells increases the size of the acute antiviral response and of the resulting memory T cell pool

26 September 2018

1 reference

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Essential role for IL-2 in the regulation of antiviral extralymphoid CD8 T cell responses.

26 September 2018

1 reference

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Lymphocytic choriomeningitis virus infection is associated with long-standing perturbation of LFA-1 expression on CD8+ T cells

26 September 2018

1 reference

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Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

26 September 2018

1 reference

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Adenoviral vaccination combined with CD40 stimulation and CTLA-4 blockage can lead to complete tumor regression in a murine melanoma model

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

B7-1 and B7-2 have overlapping, critical roles in immunoglobulin class switching and germinal center formation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

Vaccination with an adenoviral vector encoding the tumor antigen directly linked to invariant chain induces potent CD4+T-cell-independent CD8+T-cell-mediated tumor control

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4429690

MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus Vaccines

15 November 2018

1 reference

https://api.crossref.org/works/10.1038%2FMT.2014.130

7 January 2021

Interleukin-2 is indispensable for development of immunological self-tolerance

1 reference

https://api.crossref.org/works/10.1038%2FMT.2014.130

7 January 2021

Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo

1 reference

https://api.crossref.org/works/10.1038%2FMT.2014.130

7 January 2021

Molecular regulation of interleukin-2 expression by CD28 co-stimulation and anergy

1 reference

https://api.crossref.org/works/10.1038%2FMT.2014.130

7 January 2021

Th cells act via two synergistic pathways to promote antiviral CD8+ T cell responses

1 reference

https://api.crossref.org/works/10.1038%2FMT.2014.130

7 January 2021

Duration of TCR stimulation determines costimulatory requirement of T cells

1 reference

https://api.crossref.org/works/10.1038%2FMT.2014.130

7 January 2021

The fate of interleukin-2 after in vivo administration

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25023330

12 December 2020

inferred from PubMed ID database lookup

Implantation of IL-2-containing osmotic pump prolongs the survival of superantigen-reactive T cells expanded in mice injected with bacterial superantigen

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25023330

12 December 2020

inferred from PubMed ID database lookup

Tumor-infiltrating lymphocytes exhibiting high ex vivo cytolytic activity fail to prevent murine melanoma tumor growth in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25023330

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/MT.2014.130

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25023330%20AND%20SRC:MED&resulttype=core&format=json