Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites (Q35606514)

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scientific article published on 14 May 2015

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English	Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites	scientific article published on 14 May 2015

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scholarly article

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Europe PubMed Central

9 August 2017

Mechanisms of stage-transcending protection following immunization of mice with late liver stage-arresting genetically attenuated malaria parasites (English)

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Europe PubMed Central

9 August 2017

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Stefan H I Kappe

6

object named as

Stefan H I Kappe

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Europe PubMed Central

9 August 2017

Ashley M Vaughan

3

object named as

Ashley M Vaughan

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Europe PubMed Central

9 August 2017

Gladys J Keitany

2

object named as

Gladys J Keitany

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Europe PubMed Central

9 August 2017

1

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Brandon K Sack

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Europe PubMed Central

9 August 2017

author name string

Jessica L Miller

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Europe PubMed Central

9 August 2017

Ruobing Wang

5

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Europe PubMed Central

9 August 2017

publication date

14 May 2015

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Europe PubMed Central

9 August 2017

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Europe PubMed Central

9 August 2017

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Europe PubMed Central

9 August 2017

e1004855

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Europe PubMed Central

9 August 2017

5

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Europe PubMed Central

9 August 2017

copyright license

Creative Commons Attribution 4.0 International

14 May 2015

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April 2022 Public Data File from Crossref

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Immunization of mice with live-attenuated late liver stage-arresting Plasmodium yoelii parasites generates protective antibody responses to preerythrocytic stages of malaria

1 reference

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1 reference

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Cytotoxic markers associate with protection against malaria in human volunteers immunized with Plasmodium falciparum sporozoites

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CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria

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Correlates of protective immunity following whole sporozoite vaccination against malaria

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Model for in vivo assessment of humoral protection against malaria sporozoite challenge by passive transfer of monoclonal antibodies and immune serum

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Enzymes involved in plastid-targeted phosphatidic acid synthesis are essential for Plasmodium yoelii liver-stage development

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PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.

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Type II fatty acid biosynthesis is essential for Plasmodium falciparum sporozoite development in the midgut of Anopheles mosquitoes

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Protection against malaria by intravenous immunization with a nonreplicating sporozoite vaccine

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Malaria parasite liver stages render host hepatocytes susceptible to mitochondria-initiated apoptosis

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Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities

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CSP--a model for in vivo presentation of Plasmodium berghei sporozoite antigens by hepatocytes

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Pre-erythrocytic malaria vaccines: identifying the targets

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A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants

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Genetic engineering of attenuated malaria parasites for vaccination

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Malaria vaccine development: persistent challenges

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Live attenuated malaria vaccine designed to protect through hepatic CD8⁺ T cell immunity

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Cross-presentation of antigen by diverse subsets of murine liver cells.

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Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites

1 reference

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Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

1 reference

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Liver antigen-presenting cells

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Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites.

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Low doses of killed parasite in CpG elicit vigorous CD4+ T cell responses against blood-stage malaria in mice.

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The quantity and quality of African children's IgG responses to merozoite surface antigens reflect protection against Plasmodium falciparum malaria

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Protection against a malaria challenge by sporozoite inoculation

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Kinetics of mosquito-injected Plasmodium sporozoites in mice: fewer sporozoites are injected into sporozoite-immunized mice

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Immunization with radiation-attenuated Plasmodium berghei sporozoites induces liver cCD8alpha+DC that activate CD8+T cells against liver-stage malaria

1 reference

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Blood stage malaria vaccine eliciting high antigen-specific antibody concentrations confers no protection to young children in Western Kenya

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Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus.

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Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

1 reference

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Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage

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Recent insights into humoral and cellular immune responses against malaria

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Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses

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12 July 2018

Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

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Genetically attenuated Plasmodium berghei liver stages induce sterile protracted protection that is mediated by major histocompatibility complex Class I-dependent interferon-gamma-producing CD8+ T cells

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Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells

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Apoptotic Plasmodium-infected hepatocytes provide antigens to liver dendritic cells

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Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface

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Localization of organellar proteins in Plasmodium falciparum using a novel set of transfection vectors and a new immunofluorescence fixation method

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Protective T cell immunity against malaria liver stage after vaccination with live sporozoites under chloroquine treatment

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Immunity to malaria after administration of ultra-low doses of red cells infected with Plasmodium falciparum

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Protective immune responses to the 42-kilodalton (kDa) region of Plasmodium yoelii merozoite surface protein 1 are induced by the C-terminal 19-kDa region but not by the adjacent 33-kDa region

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Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal

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IgG3 antibodies to Plasmodium falciparum merozoite surface protein 2 (MSP2): increasing prevalence with age and association with clinical immunity to malaria.

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Role of complement in C-reactive-protein-mediated protection of mice from Streptococcus pneumoniae.

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Human antibody response to Plasmodium falciparum merozoite surface protein 2 is serogroup specific and predominantly of the immunoglobulin G3 subclass

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Antibodies inhibit the protease-mediated processing of a malaria merozoite surface protein.

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Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

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Plasmodium berghei sporozoite invasion is blocked in vitro by sporozoite-immobilizing antibodies.

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Role of immune serum and complement in stimulation of the metabolic burst of human neutrophils by Plasmodium falciparum.

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Cellular subsets involved in cell-mediated immunity to murine Plasmodium yoelii 17X malaria.

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12 July 2018

Antibodies to blood stage antigens of Plasmodium falciparum in rural Gambians and their relation to protection against infection

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A protective monoclonal antibody recognizes an epitope in the carboxyl-terminal cysteine-rich domain in the precursor of the major merozoite surface antigen of the rodent malarial parasite, Plasmodium yoelii.

1 reference

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Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.

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CD4+ and CD8+ T lymphocytes both contribute to acquired immunity to blood-stage Plasmodium chabaudi AS

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Antimalarial antibodies of the immunoglobulin G2a isotype modulate parasitemias in mice infected with Plasmodium yoelii

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Serum Complement and Immunity in Experimental Simian Malaria. II. Preferential Activation of Early Components and Failure of Depletion of Late Components to Inhibit Protective Immunity

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Tracking the total CD8 T cell response following whole Plasmodium vaccination.

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Involvement of CD8+ T cells in protective immunity against murine blood-stage infection with Plasmodium yoelii 17XL strain.

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Antigenicity and immunogenicity of the N-terminal 33-kDa processing fragment of the Plasmodium falciparum merozoite surface protein 1, MSP1: implications for vaccine development.

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Direct processing and presentation of antigen from malaria sporozoites by professional antigen-presenting cells in the induction of CD8 T-cell responses.

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Genetically modified Plasmodium parasites as a protective experimental malaria vaccine

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Gamma-globulin and acquired immunity to human malaria.

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Naturally acquired antibodies to the glutamate-rich protein are associated with protection against plasmodium falciparum malaria

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Fc receptors are not required for antibody-mediated protection against lethal malaria challenge in a mouse model.

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Immunization against malaria with a recombinant protein.

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Antibodies to the protective antigen of Plasmodium berghei sporozoites prevent entry into cultured cells.

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AID-/-mus-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells

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12 December 2020

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10.1371/JOURNAL.PPAT.1004855

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Europe PubMed Central

9 August 2017

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Europe PubMed Central

9 August 2017

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Europe PubMed Central

9 August 2017

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