Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase (Q35607523)

9 August 2017

1 reference

title

Toxicity of nucleoside analogues used to treat AIDS and the selectivity of the mitochondrial DNA polymerase (English)

1 reference

9 August 2017

0 references

0 references

Harold Lee

1

1 reference

9 August 2017

Jeremiah Hanes

series ordinal

2

1 reference

9 August 2017

Kenneth A Johnson

series ordinal

3

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 December 2003

1 reference

9 August 2017

1 reference

9 August 2017

42

1 reference

9 August 2017

50

1 reference

9 August 2017

14711-14719

1 reference

Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.

9 August 2017

1 reference

12 December 2020

Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

1 reference

12 December 2020

Conformational coupling in DNA polymerase fidelity

1 reference

12 December 2020

Characterization of novel reverse transcriptase and other RNA-associated catalytic activities by human DNA polymerase gamma: importance in mitochondrial DNA replication

1 reference

12 December 2020

A single residue in DNA polymerases of the Escherichia coli DNA polymerase I family is critical for distinguishing between deoxy- and dideoxyribonucleotides

1 reference

12 December 2020

Intracellular activation of 2',3'-dideoxyinosine and drug interactions in vitro

1 reference

12 December 2020

Biased incorporation of ribonucleotides on the mitochondrial L-strand accounts for apparent strand-asymmetric DNA replication.

1 reference

12 December 2020

An introduction to nucleoside and nucleotide analogues.

1 reference

12 December 2020

Mitochondrial dysfunction and nucleoside reverse transcriptase inhibitor therapy: experimental clarifications and persistent clinical questions

1 reference

12 December 2020

Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice

1 reference

12 December 2020

Mitochondrial sensitivity to AZT.

1 reference

12 December 2020

Pharmacology of nucleoside and nucleotide reverse transcriptase inhibitor-induced mitochondrial toxicity.

1 reference

12 December 2020

A strategy for liquid chromatography/tandem mass spectrometric assays of intracellular drugs: application to the validation of the triphosphorylated anabolite of antiretrovirals in peripheral blood mononuclear cells.

1 reference

12 December 2020

Exonuclease proofreading by human mitochondrial DNA polymerase

1 reference

12 December 2020

Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma

1 reference

12 December 2020

Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).

1 reference

12 December 2020

Maternally inherited hearing impairment

1 reference

12 December 2020

Deoxycytidine deaminase-resistant stereoisomer is the active form of (+/-)-2',3'-dideoxy-3'-thiacytidine in the inhibition of hepatitis B virus replication

1 reference

12 December 2020

Probing the molecular mechanisms of AZT drug resistance mediated by HIV-1 reverse transcriptase using a transient kinetic analysis

1 reference

12 December 2020

Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria

1 reference

12 December 2020

Accumulation of point mutations in mitochondrial DNA of aging mice

1 reference

12 December 2020

Mitochondrial alterations with mitochondrial DNA depletion in the nerves of AIDS patients with peripheral neuropathy induced by 2'3'-dideoxycytidine (ddC).

1 reference

12 December 2020

Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors

1 reference

12 December 2020

Fidelity of nucleotide incorporation by human mitochondrial DNA polymerase

1 reference

12 December 2020

Expression, purification, and initial kinetic characterization of the large subunit of the human mitochondrial DNA polymerase

1 reference

12 December 2020

Significant levels of intracellular stavudine triphosphate are found in HIV-infected zidovudine-treated patients

1 reference

12 December 2020

DNA polymerases: structural diversity and common mechanisms

1 reference

12 December 2020

Mammalian DNA polymerases alpha, beta, gamma, delta, and epsilon incorporate fialuridine (FIAU) monophosphate into DNA and are inhibited competitively by FIAU Triphosphate

1 reference

12 December 2020

Human mitochondrial DNA polymerase holoenzyme: reconstitution and characterization

1 reference

12 December 2020

Mitochondrial toxicity of antiviral drugs

1 reference

12 December 2020

Comparative evaluation of L-Fd4C and related nucleoside analogs as promising antiviral agents

1 reference

12 December 2020

Improved method for the simultaneous determination of d4T, 3TC and ddl intracellular phosphorylated anabolites in human peripheral-blood mononuclear cells using high-performance liquid chromatography/tandem mass spectrometry

1 reference

12 December 2020

Mitochondrial ultrastructural and molecular changes induced by zidovudine in rat hearts

1 reference

12 December 2020

Lamivudine. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection

1 reference

12 December 2020

Error-prone repair DNA polymerases in prokaryotes and eukaryotes

1 reference

12 December 2020

Clinical manifestations and management of antiretroviral nucleoside analog-related mitochondrial toxicity

1 reference

12 December 2020

Stavudine in the face of cross-resistance between HIV-1 nucleoside reverse transcriptase inhibitors: a review

1 reference

12 December 2020

Mechanisms for the anti-hepatitis B virus activity and mitochondrial toxicity of fialuridine (FIAU).

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI035596S

1 reference

9 August 2017

0 references

1 reference