The pathophysiology of polycystic ovary syndrome (Q35608887)

9 August 2017

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title

The pathophysiology of polycystic ovary syndrome (English)

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polycystic ovary syndrome

9 August 2017

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3

Gerard S Conway

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9 August 2017

Tasoula Tsilchorozidou

series ordinal

1

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PubMed ID

14678281

9 August 2017

Caroline Overton

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2

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9 August 2017

1 January 2004

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9 August 2017

Clinical Endocrinology

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9 August 2017

60

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9 August 2017

1-17

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9 August 2017

1

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Insights into the development of polycystic ovary syndrome (PCOS) from studies of prenatally androgenized female rhesus monkeys.

9 August 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Multifollicular ovaries: clinical and endocrine features and response to pulsatile gonadotropin releasing hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Serum vascular endothelial growth factor concentrations and ovarian stromal blood flow are increased in women with polycystic ovaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Functional integrity of granulosa cells from polycystic ovaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Increased insulin sensitivity and fibrinolytic capacity after dietary intervention in obese women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

The insulin-like growth factor system: basic and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

The effects of ovulation induction with gonadotrophins on the ovary and uterus and implications for assisted reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Pulsatile gonadotrophin secretion in women with polycystic ovary syndrome after gonadotrophin-releasing hormone agonist treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Increased 5alpha-reductase and normal 11beta-hydroxysteroid dehydrogenase metabolism of C19 and C21 steroids in a young population with polycystic ovarian syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

The prevalence of polycystic ovaries in women with type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Smaller LDL particle size in women with polycystic ovary syndrome compared to controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Ovarian hyperandrogenism in adult female rhesus monkeys exposed to prenatal androgen excess

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

The genetic basis of polycystic ovary syndrome

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Hypersecretion of androstenedione by isolated thecal cells from polycystic ovaries

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Continuing metformin throughout pregnancy in women with polycystic ovary syndrome appears to safely reduce first-trimester spontaneous abortion: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Influence of insulin resistance on total renin level in normotensive women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Effect of recombinant inhibin on androgen synthesis in cultured human thecal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Restored insulin sensitivity but persistently increased early insulin secretion after weight loss in obese women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: relation to reduced fetal growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Exaggerated adrenarche and hyperinsulinism in adolescent girls born small for gestational age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Effects of metformin on early pregnancy loss in the polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Internal carotid-artery response to 5% carbon dioxide in women with polycystic ovaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Unexpected effect of a nitric oxide donor on uterine artery Doppler velocimetry in oligomenorrheic women with polycystic ovaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Evidence for a genetic basis for hyperandrogenemia in polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Clinical features in women with polycystic ovaries: relationships to insulin sensitivity, insulin gene VNTR and birth weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

High ovulatory rates with use of troglitazone in clomiphene-resistant women with polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Metformin effects on clinical features, endocrine and metabolic profiles, and insulin sensitivity in polycystic ovary syndrome: a randomized, double-blind, placebo-controlled 6-month trial, followed by open, long-term clinical evaluation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Hyperinsulinemia in hyperthecosis of the ovaries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Insulin regulation of human ovarian androgens

21 January 2018

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https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Effects of metformin on spontaneous and clomiphene-induced ovulation in the polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Polycystic ovary syndrome is associated with endothelial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Mortality of women with polycystic ovary syndrome at long-term follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Effects of the insulin sensitizing drug metformin on ovarian function, follicular growth and ovulation rate in obese women with oligomenorrhoea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Lipids and lipoprotein subfractions in women with PCOS: relationship to metabolic and endocrine parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Insulin resistance is a characteristic feature of primary hypertension independent of obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Polycystic ovaries and associated metabolic abnormalities in Indian subcontinent Asian women.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

The Diabetes Prevention Program: recruitment methods and results

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Ambulatory blood pressure profiles and plasminogen activator inhibitor (PAI-1) activity in lean women with and without the polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Absence of insulin receptor gene mutations in three insulin-resistant women with the polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Pulsatile luteinizing hormone release and ovarian steroid levels in female-to-male transsexuals compared to heterosexual women

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Effects of laparoscopic ovarian drilling on serum vascular endothelial growth factor and on insulin responses to the oral glucose tolerance test in women with polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Metformin increases the ovulatory rate and pregnancy rate from clomiphene citrate in patients with polycystic ovary syndrome who are resistant to clomiphene citrate alone

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Metformin therapy in polycystic ovary syndrome reduces hyperinsulinemia, insulin resistance, hyperandrogenemia, and systolic blood pressure, while facilitating normal menses and pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Metformin therapy is associated with a decrease in plasma plasminogen activator inhibitor-1, lipoprotein(a), and immunoreactive insulin levels in patients with the polycystic ovary syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Endogenous inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 do not explain abnormal cortisol metabolism in polycystic ovary syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Polycystic ovary syndrome: lack of hypertension despite profound insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

Fetal growth, length of gestation, and polycystic ovaries in adult life

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2265.2003.01842.X

10.1046/J.1365-2265.2003.01842.X

21 January 2018

Identifiers

DOI

1 reference

9 August 2017

1 reference

PubMed ID

14678281