Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity. (Q35609287)

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scientific article published on 13 April 2015

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English	Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity.	scientific article published on 13 April 2015

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5 March 2020

Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity (English)

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5 March 2020

Chlamydia muridarum

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Chlamydia muridarum

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5 March 2020

8

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Guangming Zhong

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Jianlin Chen

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5 March 2020

Zhangsheng Yang

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5 March 2020

Xin Sun

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5 March 2020

Lingli Tang

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5 March 2020

Yiling Ding

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Min Xue

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13 April 2015

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Infection and Immunity

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2583-2592

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5 March 2020

In vitro passage selects for Chlamydia muridarum with enhanced infectivity in cultured cells but attenuated pathogenicity in mouse upper genital tract

1 reference

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12 July 2018

Plasmid-encoded Pgp3 is a major virulence factor for Chlamydia muridarum to induce hydrosalpinx in mice

1 reference

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12 July 2018

Plasmid CDS5 influences infectivity and virulence in a mouse model of Chlamydia trachomatis urogenital infection

1 reference

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12 July 2018

Complement factor C5 but not C3 contributes significantly to hydrosalpinx development in mice infected with Chlamydia muridarum

1 reference

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12 July 2018

Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology

1 reference

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12 July 2018

Lack of long-lasting hydrosalpinx in A/J mice correlates with rapid but transient chlamydial ascension and neutrophil recruitment in the oviduct following intravaginal inoculation with Chlamydia muridarum

1 reference

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12 July 2018

Signaling via tumor necrosis factor receptor 1 but not Toll-like receptor 2 contributes significantly to hydrosalpinx development following Chlamydia muridarum infection

1 reference

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12 July 2018

Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression

1 reference

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12 July 2018

Reduced live organism recovery and lack of hydrosalpinx in mice infected with plasmid-free Chlamydia muridarum

1 reference

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12 July 2018

Transformation of sexually transmitted infection-causing serovars of chlamydia trachomatis using Blasticidin for selection

1 reference

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12 July 2018

Induction of protective immunity against Chlamydia muridarum intracervical infection in DBA/1j mice.

1 reference

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12 July 2018

Plasmid deficiency in urogenital isolates of Chlamydia trachomatis reduces infectivity and virulence in a mouse model

1 reference

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12 July 2018

Oviduct infection and hydrosalpinx in DBA1/j mice is induced by intracervical but not intravaginal inoculation with Chlamydia muridarum

1 reference

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12 July 2018

Characterization of Chlamydia trachomatis plasmid-encoded open reading frames

1 reference

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12 July 2018

Structure of the Chlamydia trachomatis Immunodominant Antigen Pgp3

1 reference

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12 July 2018

Transformation of a plasmid-free, genital tract isolate of Chlamydia trachomatis with a plasmid vector carrying a deletion in CDS6 revealed that this gene regulates inclusion phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432736

12 July 2018

Chlamydia trachomatis plasmid-encoded Pgp4 is a transcriptional regulator of virulence-associated genes

1 reference

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12 July 2018

Plasmid-cured Chlamydia caviae activates TLR2-dependent signaling and retains virulence in the guinea pig model of genital tract infection

1 reference

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12 July 2018

Enhanced upper genital tract pathologies by blocking Tim-3 and PD-L1 signaling pathways in mice intravaginally infected with Chlamydia muridarum

1 reference

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A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

1 reference

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12 July 2018

Development of a transformation system for Chlamydia trachomatis: restoration of glycogen biosynthesis by acquisition of a plasmid shuttle vector

1 reference

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12 July 2018

Infectivity acts as in vivo selection for maintenance of the chlamydial cryptic plasmid

1 reference

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12 July 2018

Characterization of Pgp3, aChlamydia trachomatisPlasmid-Encoded Immunodominant Antigen

1 reference

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12 July 2018

Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract

1 reference

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12 July 2018

Mice deficient in MyD88 Develop a Th2-dominant response and severe pathology in the upper genital tract following Chlamydia muridarum infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432736

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Epidemiology of Chlamydia trachomatis infection in women and the cost-effectiveness of screening.

1 reference

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12 July 2018

Chlamydia vaccine candidates and tools for chlamydial antigen discovery

1 reference

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12 July 2018

Co-evolution of genomes and plasmids within Chlamydia trachomatis and the emergence in Sweden of a new variant strain

1 reference

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12 July 2018

Antibodies from women urogenitally infected with C. trachomatis predominantly recognized the plasmid protein pgp3 in a conformation-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432736

12 July 2018

The chlamydial plasmid-encoded protein pgp3 is secreted into the cytosol of Chlamydia-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432736

12 July 2018

The Chlamydia trachomatis plasmid is a transcriptional regulator of chromosomal genes and a virulence factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432736

12 July 2018

Plasmid-deficient Chlamydia muridarum fail to induce immune pathology and protect against oviduct disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432736

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A plasmid-cured Chlamydia muridarum strain displays altered plaque morphology and reduced infectivity in cell culture.

1 reference

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Histopathologic changes related to fibrotic oviduct occlusion after genital tract infection of mice with Chlamydia muridarum

1 reference

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Vaccines for Chlamydia trachomatis infections.

1 reference

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Immunity to murine chlamydial genital infection

1 reference

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Genome sequences of Chlamydia trachomatis MoPn and Chlamydia pneumoniae AR39.

1 reference

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Inhibition of apoptosis in chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation

1 reference

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Plasmid diversity in Chlamydia

1 reference

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Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility

1 reference

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Transcriptional regulation in the Chlamydia trachomatis pCT plasmid

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12 July 2018

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10.1128/IAI.00353-15

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5 March 2020

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