Epigenetic regulation of motor neuron cell death through DNA methylation (Q35614360)

9 August 2017

Epigenetic regulation of motor neuron cell death through DNA methylation (English)

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9 August 2017

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Barry A Chestnut

1

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9 August 2017

Qing Chang

2

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9 August 2017

Ann Price

3

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9 August 2017

Catherine Lesuisse

4

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9 August 2017

Margaret Wong

5

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9 August 2017

Lee J Martin

6

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9 August 2017

language of work or name

English

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publication date

1 November 2011

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9 August 2017

Journal of Neuroscience

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9 August 2017

31

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9 August 2017

46

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9 August 2017

16619-16636

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describes a project that uses

9 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3238138/fullTextXML

inferred from PubMed Central ID database lookup

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Glycine receptor channels in spinal motoneurons are abnormal in a transgenic mouse model of amyotrophic lateral sclerosis

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An approach to experimental synaptic pathology using green fluorescent protein-transgenic mice and gene knockout mice to show mitochondrial permeability transition pore-driven excitotoxicity in interneurons and motoneurons

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DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria

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Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases

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Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

12 July 2018

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Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation

12 July 2018

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Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.

12 July 2018

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Skeletal muscle-restricted expression of human SOD1 causes motor neuron degeneration in transgenic mice

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A genome-wide analysis of brain DNA methylation identifies new candidate genes for sporadic amyotrophic lateral sclerosis.

12 July 2018

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Solving the Dnmt2 enigma.

12 July 2018

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Epigenetic regulation of neuron-dependent induction of astroglial synaptic protein GLT1.

12 July 2018

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Experimental models for the study of neurodegeneration in amyotrophic lateral sclerosis

12 July 2018

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The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice

12 July 2018

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Glycinergic innervation of motoneurons is deficient in amyotrophic lateral sclerosis mice: a quantitative confocal analysis

12 July 2018

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Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition

12 July 2018

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Molecular regulation of DNA damage-induced apoptosis in neurons of cerebral cortex

12 July 2018

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Activity-dependent suppression of miniature neurotransmission through the regulation of DNA methylation.

12 July 2018

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Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation

12 July 2018

1 reference

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Covalent modification of DNA regulates memory formation

12 July 2018

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Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis

12 July 2018

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DNA methyltransferases: facts, clues, mysteries.

12 July 2018

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Footprinting of mammalian promoters: use of a CpG DNA methyltransferase revealing nucleosome positions at a single molecule level

12 July 2018

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Procainamide is a specific inhibitor of DNA methyltransferase 1.

12 July 2018

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Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation.

12 July 2018

1 reference

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DNA methylation and demethylation as targets for anticancer therapy

12 July 2018

1 reference

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Housekeeping proteins: a preliminary study illustrating some limitations as useful references in protein expression studies.

12 July 2018

1 reference

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DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation

12 July 2018

1 reference

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Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1

12 July 2018

1 reference

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Directed differentiation of embryonic stem cells into motor neurons

12 July 2018

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Molecular mechanisms of gene silencing mediated by DNA methylation

12 July 2018

1 reference

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DNA methylation patterns and epigenetic memory

12 July 2018

1 reference

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The expanding role of mitochondria in apoptosis

12 July 2018

1 reference

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The role of DNA methylation in mammalian epigenetics

12 July 2018

1 reference

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DNA methylation, methyltransferases, and cancer

12 July 2018

1 reference

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The DNA methyltransferases of mammals

12 July 2018

1 reference

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Maintenance-type DNA methyltransferase is highly expressed in post-mitotic neurons and localized in the cytoplasmic compartment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

DNA methyltransferase contributes to delayed ischemic brain injury.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Cloning, expression and chromosome locations of the human DNMT3 gene family

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

CpG methylation, chromatin structure and gene silencing-a three-way connection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Comparative evaluation of synaptophysin-based methods for quantification of synapses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Identification and characterization of a spinal muscular atrophy-determining gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Structure and function of DNA methyltransferases.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Methylation pattern of mouse mitochondrial DNA

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

CpG islands in vertebrate genomes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Postischemic treatment of neonatal cerebral ischemia should target autophagy.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

An epigenetic analysis of SOD1 and VEGF in ALS.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Are metallothionein genes silenced in ALS?

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Existence of a no effect level for MeIQx hepatocarcinogenicity on a background of thioacetamide-induced liver damage in rats

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Epigenetic reactivation of tumor suppressor genes by a novel small-molecule inhibitor of human DNA methyltransferases.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Dynamic expression of de novo DNA methyltransferases Dnmt3a and Dnmt3b in the central nervous system

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Early events of target deprivation/axotomy-induced neuronal apoptosis in vivo: oxidative stress, DNA damage, p53 phosphorylation and subcellular redistribution of death proteins

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

DNA base-excision repair enzyme apurinic/apyrimidinic endonuclease/redox factor-1 is increased and competent in the brain and spinal cord of individuals with amyotrophic lateral sclerosis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Rapid subcellular redistribution of Bax precedes caspase-3 and endonuclease activation during excitotoxic neuronal apoptosis in rat brain

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Immature and mature cortical neurons engage different apoptotic mechanisms involving caspase-3 and the mitogen-activated protein kinase pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Effects of cerebral ischemia in mice lacking DNA methyltransferase 1 in post-mitotic neurons.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

DNA mismatch repair and DNA methylation in adult brain neurons.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Expression of DNA methyltransferase gene in mature and immature neurons as well as proliferating cells in mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3238138

Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis

25 September 2018

1 reference

12 December 2020

Apoptosis and necrosis occur in separate neuronal populations in hippocampus and cerebellum after ischemia and are associated with differential alterations in metabotropic glutamate receptor signaling pathways

1 reference

12 December 2020

Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent

1 reference

12 December 2020

Beta-actin is not a reliable loading control in Western blot analysis

1 reference

12 December 2020

beta-tubulin is a more suitable internal control than beta-actin in western blot analysis of spinal cord tissues after traumatic injury

1 reference

12 December 2020

Putting the 'HAT' back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions

1 reference

12 December 2020

Mitochondrial DNA in mortal and immortal human cells. Genome number, integrity, and methylation

1 reference

12 December 2020

10.1523/JNEUROSCI.1639-11.2011

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference