Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma (Q35627845)

9 August 2017

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title

Biology and therapeutic potential of the interleukin-4/interleukin-13 signaling pathway in asthma (English)

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9 August 2017

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David B Corry

1

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9 August 2017

Farrah Kheradmand

series ordinal

2

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9 August 2017

publication date

1 January 2002

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Treatments in Respiratory Medicine

9 August 2017

published in

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9 August 2017

volume

1

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9 August 2017

issue

3

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9 August 2017

page(s)

185-193

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Interacting Effects of Atopy and Bronchial Hyperresponsiveness on the Annual Decline in Lung Function and the Exacerbation Rate in Asthma

9 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Asthma and irreversible airflow obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Airways obstruction in patients with long-term asthma consistent with 'irreversible asthma'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Induction and regulation of the IgE response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Inhibition of T cell costimulation abrogates airway hyperresponsiveness in a murine model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Differential regulation of IgG1 and IgE synthesis by interleukin 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin-13: central mediator of allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Receptor for interleukin 13. Interaction with interleukin 4 by a mechanism that does not involve the common gamma chain shared by receptors for interleukins 2, 4, 7, 9, and 15.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

IL-13 and IL-4 share signal transduction elements as well as receptor components in TF-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Comparison of IL-13- and IL-4-induced signaling in EBV-immortalized human B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

An interleukin (IL)-13 receptor lacking the cytoplasmic domain fails to transduce IL-13-induced signals and inhibits responses to IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

IL-4 and IL-13 activate the JAK2 tyrosine kinase and Stat6 in cultured human vascular endothelial cells through a common pathway that does not involve the gamma c chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Disruption of the murine IL-4 gene blocks Th2 cytokine responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Activated mast cells produce interleukin 13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Impaired development of Th2 cells in IL-13-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted Stat6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin (IL)-4-independent induction of immunoglobulin (Ig)E, and perturbation of T cell development in transgenic mice expressing IL-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Effects of interleukin (IL)-13 on immediate-early response gene expression, phenotype and differentiation of human mast cells. Comparison with IL-4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin 4 is localized to and released by human mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Allergen-induced airway inflammation and bronchial responsiveness in wild-type and interleukin-4-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

IL-13 in allergy: home at last

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

The IL-4 receptor: signaling mechanisms and biologic functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

IL-4 and IL-13 receptors: are they one and the same?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Biological activity of IL-4 and IL-13 on human endothelial cells: functional evidence that both cytokines act through the same receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Human ovarian-carcinoma cell lines express IL-4 and IL-13 receptors: comparison between IL-4- and IL-13-induced signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Structure of IL-13 receptor: analysis of subunit composition in cancer and immune cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Modulation of interleukin (IL)-13 binding and signaling by the gammac chain of the IL-2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Characterization and comparison of the interleukin 13 receptor with the interleukin 4 receptor on several cell types

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Identification, purification, and characterization of a soluble interleukin (IL)-13-binding protein. Evidence that it is distinct from the cloned Il-13 receptor and Il-4 receptor alpha-chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interleukin-13 is a potent activator of JAK3 and STAT6 in cells expressing interleukin-2 receptor-gamma and interleukin-4 receptor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

An IL-13 promoter polymorphism associated with increased risk of allergic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

A repeat polymorphism in interleukin-4 gene is highly associated with specific clinical phenotypes of asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

The association of atopy with a gain-of-function mutation in the alpha subunit of the interleukin-4 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Peripheral expression of Jak3 is required to maintain T lymphocyte function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Signaling via IL-2 and IL-4 in JAK3-deficient severe combined immunodeficiency lymphocytes: JAK3-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03256608

The relationship of asthma therapy and Churg-Strauss syndrome: NIH workshop summary report

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03256608

Generation and analysis of interleukin-4 deficient mice

21 January 2018

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https://api.crossref.org/works/10.1007%2FBF03256608

21 January 2018

Identifiers

DOI

10.1007/BF03256608

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9 August 2017

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