The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy (Q35627907)

9 August 2017

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title

The role of interleukin-8 and its receptors in inflammatory lung disease: implications for therapy (English)

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9 August 2017

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James E Pease

1

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ORCID Public Data File 2021

author name string

Ian Sabroe

series ordinal

2

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9 August 2017

1 January 2002

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Treatments in Respiratory Medicine

9 August 2017

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9 August 2017

1

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9 August 2017

1

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9 August 2017

19-25

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https://scigraph.springernature.com/pub.10.1007/bf03257159

9 August 2017

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Increased neutrophils and cytokines, TNF-alpha and IL-8, in induced sputum of non-asthmatic patients with chronic dry cough

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Human peripheral blood eosinophils express and release interleukin-8.

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The cellular composition of induced sputum in chronic obstructive pulmonary disease.

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In patients with chronic bronchitis a four week trial with inhaled steroids does not attenuate airway inflammation

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21 January 2018

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Specific binding of IL-8 to rabbit alpha-macroglobulin modulates IL-8 function in the lung.

21 January 2018

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21 January 2018

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Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration

21 January 2018

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Differential expression and responsiveness of chemokine receptors (CXCR1-3) by human microvascular endothelial cells and umbilical vein endothelial cells

21 January 2018

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12 December 2020

Granulocyte inflammatory markers and airway infection during acute exacerbation of chronic obstructive pulmonary disease

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12 December 2020

Effect of granulocytopenia on extravascular lung water content after microembolization.

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12 December 2020

Structure-activity relationships of interleukin-8 determined using chemically synthesized analogs. Critical role of NH2-terminal residues and evidence for uncoupling of neutrophil chemotaxis, exocytosis, and receptor binding activities

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Purification and amino acid sequencing of NAF, a novel neutrophil-activating factor produced by monocytes

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12 December 2020

Severity of asthma is related to endotoxin in house dust

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12 December 2020

IL-8 activates endothelial cell CXCR1 and CXCR2 through Rho and Rac signaling pathways

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12 December 2020

Inflammatory cells and mediators in bronchial lavage of patients with chronic obstructive pulmonary disease

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12 December 2020

Lenercept (p55 tumor necrosis factor receptor fusion protein) in severe sepsis and early septic shock: a randomized, double-blind, placebo-controlled, multicenter phase III trial with 1,342 patients

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12 December 2020

Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma

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12 December 2020

Interleukin-8 gene expression in human bronchial epithelial cells

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12 December 2020

Expression and release of interleukin-8 by human airway smooth muscle cells: inhibition by Th-2 cytokines and corticosteroids

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12 December 2020

The biologic role of interleukin-8: functional analysis and expression of CXCR1 and CXCR2 on human eosinophils

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12 December 2020

Glucocorticoids inhibit chemokine generation by human eosinophils

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

IL-8 is expressed by human peripheral blood eosinophils. Evidence for increased secretion in asthma

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12 December 2020

Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells

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12 December 2020

Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease

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12 December 2020

Lipoteichoic acid inhibits lipopolysaccharide-induced adhesion molecule expression and IL-8 release in human lung microvascular endothelial cells

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12 December 2020

Increase of chemokine levels in sputum precedes exacerbation of acute asthma attacks

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12 December 2020

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12 December 2020

Sustained high levels of circulatory interleukin-8 are associated with a poor outcome in patients with adult respiratory distress syndrome

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12 December 2020

Molecular mechanism of interleukin-8 gene expression

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12 December 2020

CD45 modulation of CXCR1 and CXCR2 in human polymorphonuclear leukocytes

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12 December 2020

Blood interleukin-8 production is increased in chemical workers with bronchitic symptoms

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12 December 2020

Studies on the interaction of IL-8 with human plasma alpha 2-macroglobulin: evidence for the presence of IL-8 complexed to alpha 2-macroglobulin in lung fluids of patients with adult respiratory distress syndrome

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12 December 2020

Upregulation of formyl-peptide and interleukin-8-induced eosinophil chemotaxis in patients with allergic asthma

1 reference

12 December 2020

Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways

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12 December 2020

Eosinophil major basic protein induces degranulation and IL-8 production by human eosinophils

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12 December 2020

The role of interleukin-5, interleukin-8 and RANTES in the chemotactic attraction of eosinophils to the allergic lung

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12 December 2020

IL-4 inhibits the expression of IL-8 from stimulated human monocytes

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12 December 2020

Free and complexed interleukin-8 in blood and bronchial mucosa in asthma

1 reference

12 December 2020

Stimulation of neutrophil interleukin-8 production by eosinophil granule major basic protein

1 reference

12 December 2020

Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression.

1 reference

12 December 2020

Constitutive production of IL-4 and IL-10 and stimulated production of IL-8 by normal peripheral blood eosinophils

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12 December 2020

Regulation of the expression of IL-8 receptor A/B by IL-8: possible functions of each receptor

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12 December 2020

Monokine-induced neutrophil chemotactic factor gene expression in human fibroblasts

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12 December 2020

Purification and partial biochemical characterization of a human monocyte-derived, neutrophil-activating peptide that lacks interleukin 1 activity.

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12 December 2020

Bronchoscopic evaluation of severe asthma. Persistent inflammation associated with high dose glucocorticoids

1 reference

12 December 2020

Human peripheral blood eosinophils produce and release interleukin-8 on stimulation with calcium ionophore

1 reference

12 December 2020

Release of neutrophil chemotactic activity during immediate hypersensitivity reactions in humans

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12 December 2020

Respiratory syncytial virus stimulates neutrophil degranulation and chemokine release

1 reference

12 December 2020

Neutrophil-activating protein ENA-78 and IL-8 exhibit different patterns of expression in lipopolysaccharide- and cytokine-stimulated human monocytes

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03257159

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9 August 2017

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1 reference

PubMed ID

14720072