A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis (Q35629250)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116824%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

A mouse model of clonal CD8+ T lymphocyte-mediated alopecia areata progressing to alopecia universalis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116824%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

1 reference

Rajshekhar Alli

1

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17 January 2020

Phuong Nguyen

series ordinal

2

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17 January 2020

John P Sundberg

series ordinal

4

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17 January 2020

language of work or name

English

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publication date

23 November 2011

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17 January 2020

published in

Journal of Immunology

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17 January 2020

volume

188

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17 January 2020

issue

1

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17 January 2020

page(s)

477-486

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Primary Follicular Dystrophy With Scarring Dermatitis in C57BL/6 Mouse Substrains Resembles Central Centrifugal Cicatricial Alopecia in Humans

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Viral infection triggers central nervous system autoimmunity via activation of CD8+ T cells expressing dual TCRs.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Retrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Complex hair cycle domain patterns and regenerative hair waves in living rodents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Alopecia areata: a tissue specific autoimmune disease of the hair follicle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

CD4+ T cells are required for the maintenance, not programming, of memory CD8+ T cells after acute infection.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

An overview of real-time quantitative PCR: applications to quantify cytokine gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

T cell receptor antagonist peptides induce positive selection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

HLA and ICAM-1 expression in alopecia areata in vivo and in vitro: the role of cytokines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

The DEBR rat: an animal model of human alopecia areata.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

History of atopy or autoimmunity increases risk of alopecia areata.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Alopecia areata following adalimumab

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Crucial role of the interleukin-6/interleukin-17 cytokine axis in the induction of arthritis by glucose-6-phosphate isomerase

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Generation of T-cell receptor retrogenic mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Interferon-gamma-deficient mice are resistant to the development of alopecia areata.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Alopecia areata in C3H/HeJ mice involves leukocyte-mediated root sheath disruption in advance of overt hair loss.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Transfer of alopecia areata in the human scalp graft/Prkdcscid (SCID) mouse system is characterized by a TH1 response

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Resistance to alopecia areata in C3H/HeJ mice is associated with increased expression of regulatory cytokines and a failure to recruit CD4+ and CD8+ cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

The 'cleavage' activities of foot-and-mouth disease virus 2A site-directed mutants and naturally occurring '2A-like' sequences

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3244525

Diabetes incidence is unaltered in glutamate decarboxylase 65-specific TCR retrogenic nonobese diabetic mice: generation by retroviral-mediated stem cell gene transfer

25 September 2018

1 reference

12 December 2020

T cell subpopulations in alopecia areata

1 reference

12 December 2020

Immunohistological study of the development of the cellular infiltrate in the pelage follicles of the DEBR model for alopecia areata

1 reference

12 December 2020

Alopecia areata in aging C3H/HeJ mice

1 reference

12 December 2020

Tumor necrosis factor alpha (TNF-alpha) gene polymorphism in alopecia areata

1 reference

12 December 2020

Lymphocyte-mediated alopecia in C57BL/6 mice following successful immunotherapy for melanoma

1 reference

12 December 2020

In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata

1 reference

12 December 2020

IFN-gamma-induced HLA-DR but not ICAM-1 expression on cultured dermal papilla cells is downregulated by TNF-alpha

1 reference

12 December 2020

Autoantibodies to hair follicles in C3H/HeJ mice with alopecia areata-like hair loss

1 reference

12 December 2020

Partial restoration of hair growth in the DEBR model for Alopecia areata after in vivo depletion of CD4+ T cells

1 reference

12 December 2020

Cutting Edge: Precursor Frequency Affects the Helper Dependence of Cytotoxic T Cells

1 reference

12 December 2020

Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice

1 reference

12 December 2020

Mediation of alopecia areata by cooperation between CD4+ and CD8+ T lymphocytes: transfer to human scalp explants on Prkdc(scid) mice

1 reference

12 December 2020

Interleukin-10-deficient mice are less susceptible to the induction of alopecia areata

1 reference

12 December 2020

The functional relevance of the type 1 cytokines IFN-gamma and IL-2 in alopecia areata of C3H/HeJ mice

1 reference

12 December 2020

Failure of two TNF-alpha blockers to influence the course of alopecia areata

1 reference

12 December 2020

Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection

1 reference

12 December 2020

On the pathogenicity of autoantigen-specific T-cell receptors

1 reference

12 December 2020

Alopecia areata universalis elicited during treatment with adalimumab

1 reference

12 December 2020

1 reference

12 December 2020

Alopecia areata universalis during treatment of rheumatoid arthritis with anti-TNF-alpha antibody (adalimumab)

1 reference

12 December 2020

Melanocytes: a possible autoimmune target in alopecia areata

1 reference

12 December 2020

Vogt-Koyanagi-Harada syndrome: Association with alopecia areata

1 reference

12 December 2020

Complete remission of alopecia universalis after allogeneic hematopoietic stem cell transplantation

1 reference

12 December 2020

Alopecia areata induced in C3H/HeJ mice by interferon-gamma: evidence for loss of immune privilege

1 reference

12 December 2020

Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1100657

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116824%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116824%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

22116824

1 reference