The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability. (Q35634874)

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5 March 2020

title

The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability (English)

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5 March 2020

6

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5 March 2020

author name string

Bryan L Krock

1

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5 March 2020

Tzipora S Eisinger-Mathason

2

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5 March 2020

Dionysios N Giannoukos

3

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5 March 2020

Jessica E Shay

4

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5 March 2020

Mercy Gohil

5

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5 March 2020

Michael S Nakazawa

7

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5 March 2020

Julie Sesen

8

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5 March 2020

Nicolas Skuli

9

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5 March 2020

M Celeste Simon

10

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5 March 2020

language of work or name

English

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publication date

8 April 2015

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5 March 2020

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5 March 2020

volume

125

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issue

21

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5 March 2020

page(s)

3263-3272

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Direct measurement of local oxygen concentration in the bone marrow of live animals

5 March 2020

cites work

1 reference

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HIF1α is a regulator of hematopoietic progenitor and stem cell development in hypoxic sites of the mouse embryo.

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FOXO3A directs a protective autophagy program in haematopoietic stem cells.

27 July 2018

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Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells

27 July 2018

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27 July 2018

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27 July 2018

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Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

27 July 2018

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The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche.

27 July 2018

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Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment

27 July 2018

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TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species

27 July 2018

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Stem cells and niches: mechanisms that promote stem cell maintenance throughout life

27 July 2018

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Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment

27 July 2018

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Hypoxia-inducible factors, stem cells, and cancer

27 July 2018

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Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo

27 July 2018

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Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia

27 July 2018

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Acute postnatal ablation of Hif-2alpha results in anemia

27 July 2018

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Enhanced purification of fetal liver hematopoietic stem cells using SLAM family receptors

27 July 2018

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

27 July 2018

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Regulation of the chemokine receptor CXCR4 by hypoxia

27 July 2018

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The HIF family member EPAS1/HIF-2α is required for normal hematopoiesis in mice

27 July 2018

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HIF-1alpha is essential for myeloid cell-mediated inflammation

27 July 2018

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Conditional disruption of the aryl hydrocarbon receptor nuclear translocator (Arnt) gene leads to loss of target gene induction by the aryl hydrocarbon receptor and hypoxia-inducible factor 1alpha

27 July 2018

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Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

27 July 2018

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27 July 2018

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The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

27 July 2018

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27 July 2018

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Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment

27 July 2018

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25 September 2018

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25 September 2018

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Synergistic induction of apoptosis in multiple myeloma cells by bortezomib and hypoxia-activated prodrug TH-302, in vivo and in vitro.

25 September 2018

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Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells

25 September 2018

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Pharmacologic stabilization of HIF-1α increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation.

25 September 2018

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25 September 2018

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Hypoxic induction of vascular endothelial growth factor regulates murine hematopoietic stem cell function in the low-oxygenic niche

25 September 2018

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Aryl hydrocarbon receptor-null allele mice have hematopoietic stem/progenitor cells with abnormal characteristics and functions.

25 September 2018

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Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug

25 September 2018

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HIF-dependent hematopoietic factors regulate the development of the embryonic vasculature

25 September 2018

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Assessing the role of hematopoietic plasticity for endothelial and hepatocyte development by non-invasive lineage tracing.

25 September 2018

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

25 September 2018

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Loss of HIF-1alpha in endothelial cells disrupts a hypoxia-driven VEGF autocrine loop necessary for tumorigenesis.

25 September 2018

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VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism

25 September 2018

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The cyclic AMP response element in the Bcl-2 promoter confers inducibility by hypoxia in neuronal cells

25 September 2018

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

25 September 2018

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Hypoxia affects mesoderm and enhances hemangioblast specification during early development

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12 December 2020

The phosphorylation of liver ribosomal proteins in vivo. Evidence that only a single small subunit protein (S6) is phosphorylated

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Pimonidazole: a novel hypoxia marker for complementary study of tumor hypoxia and cell proliferation in cervical carcinoma

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Bone marrow long label-retaining cells reside in the sinusoidal hypoxic niche

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10.1182/BLOOD-2014-10-607267

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