Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats. (Q35642646)

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scientific article published on 23 November 2011

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English	Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.	scientific article published on 23 November 2011

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17 January 2020

Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats (English)

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17 January 2020

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Kenichi Serizawa

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17 January 2020

Nobuhiko Ishizuka

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17 January 2020

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Kenji Yogo

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17 January 2020

Ken Aizawa

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17 January 2020

Yoshihito Tashiro

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17 January 2020

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23 November 2011

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17 January 2020

Cardiovascular Diabetology

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17 January 2020

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17 January 2020

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17 January 2020

Endothelial dysfunction as a potential contributor in diabetic nephropathy

1 reference

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12 July 2018

Synergism in hyperhomocysteinemia and diabetes: role of PPAR gamma and tempol

1 reference

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12 July 2018

Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism

1 reference

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12 July 2018

Role of NAD(P)H Oxidase in Superoxide Generation and Endothelial Dysfunction in Goto-Kakizaki (GK) Rats as a Model of Nonobese NIDDM

1 reference

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12 July 2018

NF-kappaB-induced oxidative stress contributes to mitochondrial and cardiac dysfunction in type II diabetes.

1 reference

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12 July 2018

The effect of tempol on endothelium-dependent vasodilatation and blood pressure.

1 reference

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12 July 2018

Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets.

1 reference

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12 July 2018

Chemistry and antihypertensive effects of tempol and other nitroxides

1 reference

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12 July 2018

NAD(P)H oxidase and endothelial dysfunction

1 reference

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12 July 2018

Angiotensin II type 1 receptor blocker ameliorates uncoupled endothelial nitric oxide synthase in rats with experimental diabetic nephropathy

1 reference

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12 July 2018

AT1-receptor blockade by telmisartan upregulates GTP-cyclohydrolase I and protects eNOS in diabetic rats

1 reference

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12 July 2018

Vascular system: role of nitric oxide in cardiovascular diseases

1 reference

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12 July 2018

Mechanisms underlying recoupling of eNOS by HMG-CoA reductase inhibition in a rat model of streptozotocin-induced diabetes mellitus.

1 reference

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12 July 2018

Current status of the background of patients with coronary artery disease in Japan

1 reference

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12 July 2018

Nicorandil inhibits serum starvation-induced apoptosis in vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Impact of nicorandil in angina: subgroup analyses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Endothelial function: a critical determinant in atherosclerosis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: Part I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Effect of nicorandil on coronary events in patients with stable angina: the Impact Of Nicorandil in Angina (IONA) randomised trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Mechanisms underlying endothelial dysfunction in diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Endothelial dysfunction of coronary resistance arteries is improved by tetrahydrobiopterin in atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Mechanisms underlying the chronic pravastatin treatment-induced improvement in the impaired endothelium-dependent aortic relaxation seen in streptozotocin-induced diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

NAD(P)H oxidase: role in cardiovascular biology and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

12 July 2018

Influence of diabetes on >10-year outcomes after percutaneous coronary intervention

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21 January 2018

Altered tetrahydrobiopterin metabolism in atherosclerosis: implications for use of oxidized tetrahydrobiopterin analogues and thiol antioxidants

1 reference

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21 January 2018

Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity

1 reference

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21 January 2018

Effects of the long-term administration of nicorandil on vascular endothelial function and the progression of arteriosclerosis

1 reference

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21 January 2018

Effects of long-term nicorandil administration on endothelial function, inflammation, and oxidative stress in patients without coronary artery disease

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil improves diabetes and rat islet beta-cell damage induced by streptozotocin in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil enhances the effect of endothelial nitric oxide under hypoxia-reoxygenation: role of the KATP channel

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Reduction of diabetes-induced oxidative stress, fibrotic cytokine expression, and renal dysfunction in protein kinase Cbeta-null mice.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

p38-MAPK is involved in restoration of the lost protection of preconditioning by nicorandil in vivo

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil attenuates NF-kappaB activation, adhesion molecule expression, and cytokine production in patients with coronary artery bypass surgery

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil attenuates FeCl(3)-induced thrombus formation through the inhibition of reactive oxygen species production

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil enhances cardiac endothelial nitric oxide synthase expression via activation of adenosine triphosphate-sensitive K channel in rat.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Effects of nicorandil on monocrotaline-induced pulmonary arterial hypertension in rats

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Nicorandil inhibits angiotensin-II-induced proliferation of cultured rat cardiac fibroblasts.

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Relationship between peroxisome proliferator-activated receptors (PPAR alpha and PPAR gamma) and endothelium-dependent relaxation in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

Effects of nicorandil on cardiovascular events in patients with coronary artery disease in the Japanese Coronary Artery Disease (JCAD) study

1 reference

https://api.crossref.org/works/10.1186%2F1475-2840-10-105

21 January 2018

In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound

1 reference

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25 September 2018

Nicorandil protects against lethal ischemic ventricular arrhythmias and up-regulates endothelial nitric oxide synthase expression and sulfonylurea receptor 2 mRNA in conscious rats with acute myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248842

25 September 2018

Potassium channel openers protect cardiac mitochondria by attenuating oxidant stress at reoxygenation

1 reference

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25 September 2018

3',4'-Dihydroxyflavonol restores endothelium-dependent relaxation in small mesenteric artery from rats with type 1 and type 2 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of carbon monoxide in impaired endothelial function mediated by acute second-hand tobacco, incense, and candle smoke exposures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of flow-mediated vasodilation in femoral and brachial arteries in healthy dogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic tempol treatment attenuates the renal hemodynamic effects induced by a heme oxygenase inhibitor in streptozotocin diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the mechanism of endothelial dysfunction in the genetically-diabetic BB rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coronary angioplasty in diabetic patients. The National Heart, Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicorandil but not ISDN upregulates endothelial nitric oxide synthase expression, preventing left ventricular remodeling and degradation of cardiac function in Dahl salt-sensitive hypertensive rats with congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nicorandil reduces myocardial no-reflow by protection of endothelial function via the activation of KATP channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/22107602

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1475-2840-10-105

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22107602%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22107602%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22107602%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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