Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria. (Q35647706)

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scientific article published on 28 December 2006

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English	Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria.	scientific article published on 28 December 2006

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scholarly article

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23 December 2019

Amodiaquine and artemether-lumefantrine select distinct alleles of the Plasmodium falciparum mdr1 gene in Tanzanian children treated for uncomplicated malaria (English)

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23 December 2019

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Plasmodium falciparum

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based on heuristic

inferred from title

Georgina S Humphreys

1

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23 December 2019

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23 December 2019

author name string

I Merinopoulos

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23 December 2019

J Ahmed

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23 December 2019

T K Mutabingwa

5

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23 December 2019

C J Sutherland

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23 December 2019

R L Hallett

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28 December 2006

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23 December 2019

Antimicrobial Agents and Chemotherapy

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23 December 2019

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991-997

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23 December 2019

3

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23 December 2019

Molecular and pharmacological determinants of the therapeutic response to artemether-lumefantrine in multidrug-resistant Plasmodium falciparum malaria

1 reference

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Selection of Plasmodium falciparum pfmdr1 alleles following therapy with artemether-lumefantrine in an area of Uganda where malaria is highly endemic

1 reference

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Carriage of chloroquine-resistant parasites and delay of effective treatment increase the risk of severe malaria in Gambian children

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pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum

1 reference

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Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial

1 reference

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Reduction of malaria transmission to Anopheles mosquitoes with a six-dose regimen of co-artemether

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pfmdr1 mutations associated with chloroquine resistance incur a fitness cost in Plasmodium falciparum

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Combination therapy counteracts the enhanced transmission of drug-resistant malaria parasites to mosquitoes

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Intercontinental spread of pyrimethamine-resistant malaria

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Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

1 reference

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Developing artemisinin based drug combinations for the treatment of drug resistant falciparum malaria: A review.

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Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine

1 reference

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Short report: association between chloroquine and amodiaquine resistance and allelic variation in the Plasmodium falciparum multiple drug resistance 1 gene and the chloroquine resistance transporter gene in isolates from the upper Nile in southern S

1 reference

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27 July 2018

The addition of artesunate to chloroquine for treatment of Plasmodium falciparum malaria in Gambian children delays, but does not prevent treatment failure.

1 reference

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Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1.

1 reference

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27 July 2018

Amodiaquine for treating malaria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1803116

27 July 2018

Molecular determination of point mutation haplotypes in the dihydrofolate reductase and dihydropteroate synthase of Plasmodium falciparum in three districts of northern Tanzania

1 reference

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27 July 2018

Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations

1 reference

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27 July 2018

A molecular marker for chloroquine-resistant falciparum malaria

1 reference

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Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

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27 July 2018

The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.

1 reference

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Pyrimethamine and proguanil resistance-conferring mutations in Plasmodium falciparum dihydrofolate reductase: polymerase chain reaction methods for surveillance in Africa.

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27 July 2018

Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y.

1 reference

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25 September 2018

In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemether-lumefantrine (Coartem).

1 reference

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Differential effects of 4-aminoquinoline-containing antimalarial drugs on hemoglobin digestion in Plasmodium falciparum-infected erythrocytes

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The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin

1 reference

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Biased distribution of msp1 and msp2 allelic variants in Plasmodium falciparum populations in Thailand.

1 reference

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Antimalarial drug resistance and combination chemotherapy

1 reference

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Pharmacokinetics of mefloquine combined with artesunate in children with acute falciparum malaria.

1 reference

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25 September 2018

Identifiers

10.1128/AAC.00875-06

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23 December 2019

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23 December 2019

1 reference

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23 December 2019

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