Estrogen receptor-Beta variants are associated with increased risk of Alzheimer's disease in women with down syndrome. (Q35649433)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156442%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Estrogen receptor-Beta variants are associated with increased risk of Alzheimer's disease in women with down syndrome (English)

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18 January 2020

0 references

2

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18 January 2020

Warren B Zigman

7

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18 January 2020

author name string

Qi Zhao

1

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18 January 2020

Deborah Pang

3

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18 January 2020

Alexis Temkin

4

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18 January 2020

Naeun Park

5

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18 January 2020

Sarah C Janicki

6

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18 January 2020

Wayne Silverman

8

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18 January 2020

Benjamin Tycko

9

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18 January 2020

Nicole Schupf

10

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18 January 2020

publication date

8 December 2011

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Dementia and Geriatric Cognitive Disorders

18 January 2020

published in

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18 January 2020

volume

32

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18 January 2020

issue

4

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18 January 2020

page(s)

241-249

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Age-specific effects of estrogen receptors' polymorphisms on the bone traits in healthy fertile women: the BONTURNO study

18 January 2020

cites work

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Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome.

12 July 2018

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Bioavailable estradiol and age at onset of Alzheimer's disease in postmenopausal women with Down syndrome

12 July 2018

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12 July 2018

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Estrogen receptor beta (ESR2) polymorphisms in familial and sporadic breast cancer

12 July 2018

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Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women

12 July 2018

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Estrogen-metabolizing gene COMT polymorphism synergistic APOE epsilon4 allele increases the risk of Alzheimer disease.

12 July 2018

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12 July 2018

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Mesostriatal and mesolimbic projections of midbrain neurons immunoreactive for estrogen receptor beta or androgen receptors in rats

12 July 2018

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Onset of dementia is associated with age at menopause in women with Down's syndrome

12 July 2018

1 reference

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Estrogen-mediated neuroprotection against beta-amyloid toxicity requires expression of estrogen receptor alpha or beta and activation of the MAPK pathway

12 July 2018

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Disruption of estrogen receptor beta gene impairs spatial learning in female mice

12 July 2018

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Estrogens, selective estrogen receptor modulators, and dementia: what is the evidence?

12 July 2018

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Invited review: Estrogens effects on the brain: multiple sites and molecular mechanisms

12 July 2018

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Increased expression of estrogen receptor alpha and beta in the nucleus basalis of Meynert in Alzheimer's disease.

12 July 2018

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The estrogen receptor beta subtype: a novel mediator of estrogen action in neuroendocrine systems

12 July 2018

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Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system

12 July 2018

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Amyloid beta-protein toxicity and oxidative stress in Alzheimer's disease

12 July 2018

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Early menopause in women with Down's syndrome

12 July 2018

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Estrogen regulates metabolism of Alzheimer amyloid beta precursor protein

12 July 2018

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Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats

12 July 2018

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The pathological association between Down syndrome and Alzheimer disease

12 July 2018

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Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease.

12 July 2018

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A prospective study of Alzheimer disease in Down syndrome.

12 July 2018

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Estrogen receptors colocalize with low-affinity nerve growth factor receptors in cholinergic neurons of the basal forebrain

12 July 2018

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12 July 2018

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Genetic variation of CYP19 (aromatase) gene influences age at onset of Alzheimer's disease in women

25 September 2018

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Estrogen receptor beta gene variant is associated with vascular dementia in elderly women

25 September 2018

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25 September 2018

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Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory

25 September 2018

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Association of CA repeat polymorphism in estrogen receptor beta gene with postmenopausal osteoporosis in Chinese

25 September 2018

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Estrogen receptor beta gene (ESRbeta) 3'-UTR variants in Alzheimer disease.

25 September 2018

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Estrogen receptor beta (ESR2) polymorphisms in interaction with estrogen receptor alpha (ESR1) and insulin-like growth factor I (IGF1) variants influence the risk of fracture in postmenopausal women.

25 September 2018

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Estrogen receptor alpha and APOEepsilon4 polymorphisms interact to increase risk for sporadic AD in Italian females

25 September 2018

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Association of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein E concentrations.

25 September 2018

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Interaction between CYP19 aromatase and butyrylcholinesterase genes increases Alzheimer's disease risk

25 September 2018

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Estrogen receptor-alpha variants are associated with lipoprotein size distribution and particle levels in women: the Framingham Heart Study

25 September 2018

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Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3250648

Estrogen receptor genotypes and haplotypes associated with breast cancer risk

25 September 2018

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Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease

25 September 2018

1 reference

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Obesity enhances verbal memory in postmenopausal women with Down syndrome

25 September 2018

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Estrogen receptor 1 polymorphisms and risk of cognitive impairment in older women

25 September 2018

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Hippocampal estrogen beta-receptor immunoreactivity is increased in Alzheimer's disease

25 September 2018

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Are the estrogen receptors involved in Alzheimer's disease?

25 September 2018

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Estrogen receptor gene polymorphisms in patients with Alzheimer's disease, vascular dementia and alcohol-associated dementia.

25 September 2018

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Interaction between estrogen receptor 1 and the epsilon4 allele of apolipoprotein E increases the risk of familial Alzheimer's disease in women.

25 September 2018

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Association of the estrogen receptor alpha gene polymorphisms with sporadic Alzheimer's disease.

25 September 2018

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Comparative distribution of estrogen receptor-alpha (ER-alpha) and beta (ER-beta) mRNA in the rat pituitary, gonad, and reproductive tract

25 September 2018

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Estrogen therapy in postmenopausal women: effects on cognitive function and dementia

25 September 2018

1 reference

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Diagnosis of dementia in individuals with intellectual disability.

25 September 2018

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Prevalence of dementia in adults with and without Down syndrome.

25 September 2018

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Investigations of a CA repeat in the oestrogen receptor beta gene in patients with Alzheimer's disease

25 September 2018

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12 December 2020

Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI

1 reference

12 December 2020

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

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12 December 2020

Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons

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12 December 2020

Deletion mapping of two potential chromosome 14 tumor suppressor gene loci in ovarian carcinoma

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12 December 2020

T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures

1 reference

12 December 2020

Association of repeat polymorphisms in the estrogen receptors alpha, beta (ESR1, ESR2) and androgen receptor (AR) genes with the occurrence of breast cancer

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12 December 2020

Oestrogen receptor beta (ERbeta) polymorphism and its influence on breast cancer risk

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12 December 2020

Identifiers

DOI

10.1159/000334522

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156442%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22156442%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

22156442

1 reference