Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice (Q35650069)

9 August 2017

Curcumin Treatment Improves Motor Behavior in α-Synuclein Transgenic Mice (English)

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9 August 2017

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Kateri J Spinelli

1

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author name string

Valerie R Osterberg

2

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9 August 2017

Charles K Meshul

3

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9 August 2017

Amala Soumyanath

4

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9 August 2017

Vivek K Unni

5

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9 August 2017

language of work or name

English

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publication date

2 June 2015

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9 August 2017

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9 August 2017

10

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9 August 2017

6

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9 August 2017

e0128510

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Creative Commons CC0 License

9 August 2017

start time

2 June 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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cites work

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Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo

27 July 2018

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Curcumin suppresses soluble tau dimers and corrects molecular chaperone, synaptic, and behavioral deficits in aged human tau transgenic mice

27 July 2018

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Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction

27 July 2018

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The clinical applications of curcumin: current state and the future

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Spatiotemporal variability during gait initiation in Parkinson's disease

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Curcumin prevents aggregation in α-synuclein by increasing reconfiguration rate.

27 July 2018

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E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment

27 July 2018

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Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples

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Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration

27 July 2018

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Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

27 July 2018

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Curcumin inhibits aggregation of alpha-synuclein

27 July 2018

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Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

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Curcumin's biphasic hormetic response on proteasome activity and heat-shock protein synthesis in human keratinocytes

27 July 2018

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Gait dynamics in mouse models of Parkinson's disease and Huntington's disease

27 July 2018

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Lysosomal pathology associated with alpha-synuclein accumulation in transgenic models using an eGFP fusion protein.

27 July 2018

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

27 July 2018

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The role of alpha-synuclein in Parkinson's disease: insights from animal models

27 July 2018

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alpha-Synuclein is phosphorylated in synucleinopathy lesions

27 July 2018

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Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice.

27 July 2018

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Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein

25 September 2018

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Binding of curcumin to senile plaques and cerebral amyloid angiopathy in the aged brain of various animals and to neurofibrillary tangles in Alzheimer's brain

25 September 2018

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Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model

25 September 2018

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Treadmill gait analysis characterizes gait alterations in Parkinson's disease and amyotrophic lateral sclerosis mouse models

25 September 2018

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Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease

25 September 2018

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Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

25 September 2018

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Biotransformation of curcumin through reduction and glucuronidation in mice.

25 September 2018

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Gait variability and basal ganglia disorders: stride-to-stride variations of gait cycle timing in Parkinson's disease and Huntington's disease

25 September 2018

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Quantitative analysis of gait in Parkinson patients: increased variability of stride length

25 September 2018

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PubMed

12 December 2020

Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism

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PubMed

12 December 2020

Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC-MS/MS

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PubMed

12 December 2020

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12 December 2020

10.1371/JOURNAL.PONE.0128510

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DOI

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9 August 2017

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9 August 2017

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