Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH. (Q35650727)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22005042%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

Small molecule positive allosteric modulation of TRPV1 activation by vanilloids and acidic pH (English)

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14 January 2020

7

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14 January 2020

author name string

Krisztian Kaszas

1

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14 January 2020

Jason M Keller

2

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14 January 2020

Claudio Coddou

3

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14 January 2020

Santosh K Mishra

4

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14 January 2020

Mark A Hoon

5

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14 January 2020

Stanko Stojilkovic

6

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14 January 2020

Michael J Iadarola

8

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14 January 2020

language of work or name

English

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publication date

17 October 2011

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Journal of Pharmacology and Experimental Therapeutics

14 January 2020

published in

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14 January 2020

volume

340

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14 January 2020

issue

1

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14 January 2020

page(s)

152-160

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Ablation of rat TRPV1-expressing Adelta/C-fibers with resiniferatoxin: analysis of withdrawal behaviors, recovery of function and molecular correlates

14 January 2020

cites work

1 reference

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TRPV1-lineage neurons are required for thermal sensation

12 July 2018

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An update on the pathophysiology of complex regional pain syndrome

12 July 2018

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Prolonged analgesic response of cornea to topical resiniferatoxin, a potent TRPV1 agonist

12 July 2018

1 reference

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Neuropathic pain: a maladaptive response of the nervous system to damage

12 July 2018

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Therapeutic potential of vanilloid receptor TRPV1 agonists and antagonists as analgesics: Recent advances and setbacks

12 July 2018

1 reference

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NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia: a randomised, double-blind study

12 July 2018

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Structure-activity relationships of 1,4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1)

12 July 2018

1 reference

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Design and synthesis of peripherally restricted transient receptor potential vanilloid 1 (TRPV1) antagonists

12 July 2018

1 reference

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Calcium transport mechanisms of PC12 cells.

12 July 2018

1 reference

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Uncoupling proton activation of vanilloid receptor TRPV1.

12 July 2018

1 reference

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Increased sensitivity of desensitized TRPV1 by PMA occurs through PKCepsilon-mediated phosphorylation at S800.

12 July 2018

1 reference

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Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model

12 July 2018

1 reference

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Biochemical pharmacology of the vanilloid receptor TRPV1. An update

12 July 2018

1 reference

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Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control

12 July 2018

1 reference

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Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1).

12 July 2018

1 reference

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Peripherally induced resiniferatoxin analgesia

12 July 2018

1 reference

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Anandamide activates vanilloid receptor 1 (VR1) at acidic pH in dorsal root ganglia neurons and cells ectopically expressing VR1.

12 July 2018

1 reference

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Acid potentiation of the capsaicin receptor determined by a key extracellular site

12 July 2018

1 reference

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Conserved Ca2+-antagonist-binding properties and putative folding structure of a recombinant high-affinity dihydropyridine-binding domain.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251023

Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation

12 July 2018

1 reference

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The cloned capsaicin receptor integrates multiple pain-producing stimuli

12 July 2018

1 reference

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Treatment of intractable pain with topical large-dose capsaicin: preliminary report

12 July 2018

1 reference

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The capsaicin receptor: a heat-activated ion channel in the pain pathway

12 July 2018

1 reference

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Capsazepine block of voltage-activated calcium channels in adult rat dorsal root ganglion neurones in culture

12 July 2018

1 reference

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Capsazepine, a vanilloid receptor antagonist, inhibits nicotinic acetylcholine receptors in rat trigeminal ganglia

12 July 2018

1 reference

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Ca2+ channel ligands: structure-function relationships of the 1,4-dihydropyridines

12 July 2018

1 reference

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Painful neuropathy: altered central processing maintained dynamically by peripheral input

12 July 2018

1 reference

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Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial

12 July 2018

1 reference

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Structural determinants of gating in the TRPV1 channel.

25 September 2018

1 reference

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Proton activation does not alter antagonist interaction with the capsaicin-binding pocket of TRPV1.

25 September 2018

1 reference

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Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling.

25 September 2018

1 reference

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Vanilloid receptor 1 regulates multiple calcium compartments and contributes to Ca2+-induced Ca2+ release in sensory neurons.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251023

Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251023

Thermoregulatory effects of resiniferatoxin in the mouse: comparison with capsaicin.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251023

25 September 2018

Identifiers

DOI

10.1124/JPET.111.183053

1 reference

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release_kanmqnirpjarfpca3hu7s4pri4

14 January 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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14 January 2020

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