In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders (Q35654128)

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scientific article published on March 2011

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English	In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders	scientific article published on March 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

In vivo positron emission tomographic imaging of glial responses to amyloid-beta and tau pathologies in mouse models of Alzheimer's disease and related disorders (English)

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Europe PubMed Central

PubMed publication ID

9 August 2017

Alzheimer's disease

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John Q. Trojanowski

10

object named as

John Q Trojanowski

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PubMed publication ID

9 August 2017

Matthias Staufenbiel

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object named as

Matthias Staufenbiel

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9 August 2017

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object named as

Tetsuya Suhara

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9 August 2017

author name string

Jun Maeda

1

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9 August 2017

Ming-Rong Zhang

2

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9 August 2017

Takashi Okauchi

3

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9 August 2017

Bin Ji

4

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9 August 2017

Maiko Ono

5

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9 August 2017

Satoko Hattori

6

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9 August 2017

Katsushi Kumata

7

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9 August 2017

Nobuhisa Iwata

8

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9 August 2017

Takaomi C Saido

9

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9 August 2017

Virginia M-Y Lee

11

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9 August 2017

Takami Tomiyama

13

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9 August 2017

Hiroshi Mori

14

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9 August 2017

Toshimitsu Fukumura

15

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9 August 2017

Makoto Higuchi

17

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9 August 2017

language of work or name

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publication date

1 March 2011

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9 August 2017

Journal of Neuroscience

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9 August 2017

31

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9 August 2017

12

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Europe PubMed Central

PubMed publication ID

9 August 2017

4720-4730

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Europe PubMed Central

PubMed publication ID

9 August 2017

Quantitative analysis of peripheral benzodiazepine receptor in the human brain using PET with (11)C-AC-5216.

1 reference

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27 July 2018

Serial PIB and MRI in normal, mild cognitive impairment and Alzheimer's disease: implications for sequence of pathological events in Alzheimer's disease

1 reference

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The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells

1 reference

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Microglial activation and amyloid deposition in mild cognitive impairment: a PET study

1 reference

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The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders

1 reference

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11C-AC-5216: a novel PET ligand for peripheral benzodiazepine receptors in the primate brain

1 reference

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Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

1 reference

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A comparison of the high-affinity peripheral benzodiazepine receptor ligands DAA1106 and (R)-PK11195 in rat models of neuroinflammation: implications for PET imaging of microglial activation

1 reference

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Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model

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Tau suppression in a neurodegenerative mouse model improves memory function

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Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B

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NF-kappa B functions in synaptic signaling and behavior

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Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

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Alpha-synuclein in Lewy bodies

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Distribution volume ratios without blood sampling from graphical analysis of PET data

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In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers: a PET and MRI study

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25 September 2018

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

1 reference

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In-vivo visualization of key molecular processes involved in Alzheimer's disease pathogenesis: Insights from neuroimaging research in humans and rodent models

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Evaluation of N-benzyl-N-[11C]methyl-2- (7-methyl-8-oxo-2-phenyl-7,8-dihydro-9H-purin-9-yl)acetamide ([11C]DAC) as a novel translocator protein (18 kDa) radioligand in kainic acid-lesioned rat.

1 reference

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25 September 2018

Visualization of brain amyloid and microglial activation in mouse models of Alzheimer's disease

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[18F]FEAC and [18F]FEDAC: Two novel positron emission tomography ligands for peripheral-type benzodiazepine receptor in the brain

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Carbon 11-labeled Pittsburgh Compound B and carbon 11-labeled (R)-PK11195 positron emission tomographic imaging in Alzheimer disease.

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Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

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Increased binding of peripheral benzodiazepine receptor in Alzheimer's disease measured by positron emission tomography with [11C]DAA1106.

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PENN neurodegenerative disease research - in the spirit of Benjamin Franklin.

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In vitro and ex vivo autoradiography studies on peripheral-type benzodiazepine receptor binding using [11C]AC-5216 in normal and kainic acid-lesioned rats

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Longitudinal, quantitative assessment of amyloid, neuroinflammation, and anti-amyloid treatment in a living mouse model of Alzheimer's disease enabled by positron emission tomography

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Novel peripheral benzodiazepine receptor ligand [11C]DAA1106 for PET: an imaging tool for glial cells in the brain

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Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies

1 reference

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Identifiers

10.1523/JNEUROSCI.3076-10.2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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