Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh. (Q35655638)

9 August 2017

title

Chondrocytic Atf4 regulates osteoblast differentiation and function via Ihh. (English)

1 reference

9 August 2017

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Weiguang Wang

1

1 reference

9 August 2017

Na Lian

2

1 reference

9 August 2017

Yun Ma

3

1 reference

9 August 2017

Lingzhen Li

4

1 reference

9 August 2017

Richard C Gallant

5

1 reference

9 August 2017

Florent Elefteriou

6

1 reference

9 August 2017

Xiangli Yang

7

1 reference

9 August 2017

language of work or name

English

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publication date

21 December 2011

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9 August 2017

number of pages

11

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based on heuristic

inferred from page(s)

published in

Development

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9 August 2017

volume

139

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9 August 2017

issue

3

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9 August 2017

page(s)

601-611

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Osteoblast precursors, but not mature osteoblasts, move into developing and fractured bones along with invading blood vessels.

9 August 2017

cites work

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The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization

12 July 2018

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Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.

12 July 2018

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Partial rescue of postnatal growth plate abnormalities in Ihh mutants by expression of a constitutively active PTH/PTHrP receptor

12 July 2018

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The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts

12 July 2018

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Vimentin inhibits ATF4-mediated osteocalcin transcription and osteoblast differentiation

12 July 2018

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12 July 2018

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12 July 2018

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Indian hedgehog signals independently of PTHrP to promote chondrocyte hypertrophy

12 July 2018

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Tamoxifen-inducible gene deletion reveals a distinct cell type associated with trabecular bone, and direct regulation of PTHrP expression and chondrocyte morphology by Ihh in growth region cartilage.

12 July 2018

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Indian Hedgehog produced by postnatal chondrocytes is essential for maintaining a growth plate and trabecular bone

12 July 2018

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Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase

12 July 2018

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Kinetics of tamoxifen-regulated Cre activity in mice using a cartilage-specific CreER(T) to assay temporal activity windows along the proximodistal limb skeleton

12 July 2018

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Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation

12 July 2018

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Indian hedgehog signaling pathway: expression and regulation in pancreatic cancer

12 July 2018

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ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology; implication for Coffin-Lowry Syndrome

12 July 2018

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Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog

12 July 2018

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12 July 2018

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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

12 July 2018

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12 July 2018

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Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

12 July 2018

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Hedgehog and its patched-smoothened receptor complex: a novel signalling mechanism at the cell surface

12 July 2018

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Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

12 July 2018

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Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene

12 July 2018

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12 July 2018

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Use of a new rat chondrosarcoma cell line to delineate a 119-base pair chondrocyte-specific enhancer element and to define active promoter segments in the mouse pro-alpha 1(II) collagen gene

12 July 2018

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12 July 2018

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An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion

12 July 2018

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25 September 2018

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25 September 2018

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Hedgehog promotes primary osteoblast differentiation and increases PTHrP mRNA expression and iPTHrP secretion.

25 September 2018

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25 September 2018

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Expression of Indian hedgehog in osteoblasts and its posttranscriptional regulation by transforming growth factor-beta.

25 September 2018

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Developmental expression of a type II collagen/beta-galactosidase fusion gene in transgenic mice

25 September 2018

1 reference

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A 182 bp fragment of the mouse pro alpha 1(II) collagen gene is sufficient to direct chondrocyte expression in transgenic mice

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22190639

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Characterization of Osf1, an osteoblast-specific transcription factor binding to a critical cis-acting element in the mouse Osteocalcin promoters

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22190639

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1242/DEV.069575

1 reference

9 August 2017

1 reference

9 August 2017

1 reference