Silencing Hsp25/Hsp27 gene expression augments proteasome activity and increases CD8+ T-cell-mediated tumor killing and memory responses. (Q35656156)

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19 January 2020

title

Silencing Hsp25/Hsp27 gene expression augments proteasome activity and increases CD8+ T-cell-mediated tumor killing and memory responses (English)

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19 January 2020

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6

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19 January 2020

author name string

Ganachari M Nagaraja

1

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19 January 2020

Punit Kaur

2

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19 January 2020

William Neumann

3

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19 January 2020

Edwina E Asea

4

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19 January 2020

María A Bausero

5

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19 January 2020

Alexzander Asea

7

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19 January 2020

publication date

20 December 2011

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Cancer Prevention Research

19 January 2020

published in

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19 January 2020

volume

5

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19 January 2020

issue

1

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19 January 2020

page(s)

122-137

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Chaperone Hsp27 modulates AUF1 proteolysis and AU-rich element-mediated mRNA degradation.

19 January 2020

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MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation.

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Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.

27 July 2018

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27 July 2018

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Influence of Hsp70 and HLA-E on the killing of leukemic blasts by cytokine/Hsp70 peptide-activated human natural killer (NK) cells.

27 July 2018

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Small interference RNA targeting heat-shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase-3 activation in vitro

27 July 2018

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HSP27 favors ubiquitination and proteasomal degradation of p27Kip1 and helps S-phase re-entry in stressed cells

27 July 2018

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Increased Hsp27 after androgen ablation facilitates androgen-independent progression in prostate cancer via signal transducers and activators of transcription 3-mediated suppression of apoptosis

27 July 2018

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Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27

27 July 2018

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Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells

27 July 2018

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Heat shock protein 70 (Hsp70) membrane expression on head-and-neck cancer biopsy-a target for natural killer (NK) cells.

27 July 2018

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HSP27 is a ubiquitin-binding protein involved in I-kappaBalpha proteasomal degradation

27 July 2018

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Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction

27 July 2018

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Molecular sequelae of proteasome inhibition in human multiple myeloma cells

27 July 2018

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New functions for the matrix metalloproteinases in cancer progression

27 July 2018

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Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance

27 July 2018

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Structural basis for the activation of 20S proteasomes by 11S regulators

27 July 2018

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Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28.

27 July 2018

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Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas

27 July 2018

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Mechanisms of MHC class I--restricted antigen processing

27 July 2018

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Regulation of actin filament dynamics by p38 map kinase-mediated phosphorylation of heat shock protein 27.

27 July 2018

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27 July 2018

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A role for the proteasome regulator PA28alpha in antigen presentation

27 July 2018

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The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines.

27 July 2018

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27 July 2018

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27 July 2018

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25 September 2018

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25 September 2018

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Heat shock protein 70 membrane expression and melanoma-associated marker phenotype in primary and metastatic melanoma

25 September 2018

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Expression of the proteasome activator PA28 rescues the presentation of a cytotoxic T lymphocyte epitope on melanoma cells.

25 September 2018

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Heat shock protein 27 plays two distinct roles in controlling human breast cancer cell migration on laminin-5.

25 September 2018

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Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy

25 September 2018

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12 December 2020

An Hsp70 peptide initiates NK cell killing of leukemic blasts after stem cell transplantation

1 reference

12 December 2020

Stress response protein (srp-27) determination in primary human breast carcinomas: clinical, histologic, and prognostic correlations

1 reference

12 December 2020

The role of Ly49A and 5E6(Ly49C) molecules in hybrid resistance mediated by murine natural killer cells against normal T cell blasts

1 reference

12 December 2020

Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

1 reference

12 December 2020

Heat shock protein 27 overexpression in breast cancer lymph node metastasis

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12 December 2020

Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo

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12 December 2020

The small heat-shock protein alpha B-crystallin promotes FBX4-dependent ubiquitination

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12 December 2020

Membrane-bound heat shock protein 70 (Hsp70) in acute myeloid leukemia: a tumor specific recognition structure for the cytolytic activity of autologous NK cells

1 reference

12 December 2020

10.1158/1940-6207.CAPR-11-0121

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22185976%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22185976%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

22185976

1 reference