CDDO-methyl ester delays breast cancer development in BRCA1-mutated mice. (Q35656210)

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13 February 2020

title

CDDO-methyl ester delays breast cancer development in BRCA1-mutated mice (English)

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13 February 2020

7

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13 February 2020

author name string

Eun-Hee Kim

1

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13 February 2020

Chuxia Deng

2

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13 February 2020

Michael B Sporn

3

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13 February 2020

Darlene B Royce

4

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13 February 2020

Renee Risingsong

5

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13 February 2020

Charlotte R Williams

6

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13 February 2020

publication date

20 September 2011

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Cancer Prevention Research

13 February 2020

published in

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13 February 2020

volume

5

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13 February 2020

issue

1

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13 February 2020

page(s)

89-97

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Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR

13 February 2020

cites work

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Bardoxolone methyl and kidney function in CKD with type 2 diabetes

12 July 2018

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12 July 2018

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Loss of BRCA1 leads to an increase in epidermal growth factor receptor expression in mammary epithelial cells, and epidermal growth factor receptor inhibition prevents estrogen receptor-negative cancers in BRCA1-mutant mice

12 July 2018

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CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells

12 July 2018

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New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress

12 July 2018

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The role of BRCA mutation testing in determining breast cancer therapy

12 July 2018

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Risk-reducing strategies for women carrying BRCA1/2 mutations with a focus on prophylactic surgery

12 July 2018

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The role of the microenvironment in mammary gland development and cancer

12 July 2018

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Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.

12 July 2018

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Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide

12 July 2018

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Trophic macrophages in development and disease

12 July 2018

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Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid

12 July 2018

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Mouse models for BRCA1 associated tumorigenesis: from fundamental insights to preclinical utility

12 July 2018

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A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin

12 July 2018

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Cancer-related inflammation

12 July 2018

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Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.

12 July 2018

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The synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells

12 July 2018

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Breast cancer risk associated with BRCA1 and BRCA2 in diverse populations

12 July 2018

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A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland

12 July 2018

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Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.

12 July 2018

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The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta

12 July 2018

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Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist

12 July 2018

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The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer

12 July 2018

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12 July 2018

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Targeting fatty acid synthase: potential for therapeutic intervention in her-2/neu-overexpressing breast cancer

12 July 2018

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12 July 2018

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12 July 2018

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Multiple genetic changes are associated with mammary tumorigenesis in Brca1 conditional knockout mice

12 July 2018

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12 July 2018

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12 July 2018

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25 September 2018

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Design, synthesis, and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets

25 September 2018

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Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the hum

25 September 2018

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The retinoid X receptor-selective retinoid, LGD1069, prevents the development of estrogen receptor-negative mammary tumors in transgenic mice.

25 September 2018

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A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production

25 September 2018

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Effect of bilateral oophorectomy on mammary tumor formation in BRCA1 mutant mice

25 September 2018

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12 December 2020

Design and synthesis of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, a novel and highly active inhibitor of nitric oxide production in mouse macrophages

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12 December 2020

Perspective: The big C - for Chemoprevention

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12 December 2020

Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD

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12 December 2020

"MAPping" the course of chemoprevention in breast cancer

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12 December 2020

10.1158/1940-6207.CAPR-11-0359

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21933912%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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13 February 2020

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