Of mice and MEN1: Insulinomas in a conditional mouse knockout (Q35660901)

9 August 2017

Of mice and MEN1: Insulinomas in a conditional mouse knockout (English)

1 reference

9 August 2017

10

1 reference

9 August 2017

17

Francis S Collins

1 reference

9 August 2017

Helena Edlund

9

0 references

author name string

Judy S Crabtree

1

1 reference

9 August 2017

Peter C Scacheri

2

1 reference

9 August 2017

Jerrold M Ward

3

1 reference

9 August 2017

Sara R McNally

4

1 reference

9 August 2017

Gary P Swain

5

1 reference

9 August 2017

Cristina Montagna

6

1 reference

9 August 2017

Jeffrey H Hager

7

1 reference

9 August 2017

Douglas Hanahan

8

1 reference

9 August 2017

Lisa Garrett-Beal

11

1 reference

9 August 2017

A Lee Burns

12

1 reference

9 August 2017

Thomas Ried

13

1 reference

9 August 2017

Settara C Chandrasekharappa

14

1 reference

9 August 2017

Stephen J Marx

15

1 reference

9 August 2017

Allen M Spiegel

16

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 September 2003

1 reference

Molecular and Cellular Biology

9 August 2017

1 reference

9 August 2017

23

1 reference

9 August 2017

6075-6085

1 reference

9 August 2017

17

1 reference

The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene

9 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Germ line transmission of the Cdk4(R24C) mutation facilitates tumorigenesis and escape from cellular senescence

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Menin interacts directly with the homeobox-containing protein Pem

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Menin, a gene product responsible for multiple endocrine neoplasia type 1, interacts with the putative tumor metastasis suppressor nm23

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Tumor cells utilize multiple pathways to down-modulate apoptosis. Lessons from a mouse model of islet cell carcinogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Characterization of the mouse Men1 gene and its expression during development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Menin, the product of the MEN1 gene, is a nuclear protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Characterization of mutations in patients with multiple endocrine neoplasia type 1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Mutations of the MEN1 tumor suppressor gene in pituitary tumors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Somatic mutation of the MEN1 gene in parathyroid tumours.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Positional cloning of the gene for multiple endocrine neoplasia-type 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Targeted oncogene activation by site-specific recombination in transgenic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Z/AP, a double reporter for cre-mediated recombination.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=180910

Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistry

25 September 2018

1 reference

12 December 2020

Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu

1 reference

12 December 2020

Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas

1 reference

12 December 2020

Alterations of the MEN1 gene in sporadic parathyroid tumors

1 reference

12 December 2020

Mutation analysis of the MEN1 gene in Belgian patients with multiple endocrine neoplasia type 1 and related diseases

1 reference

12 December 2020

10.1128/MCB.23.17.6075-6085.2003

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference