Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum (Q35662134)

9 August 2017

title

Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum (English)

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5a,8a-Epidioxyergosta-6,9(11),22-trien-3

9 August 2017

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(5R,10S,13R,14R,17R)-17-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one

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3-Hydroxy-17-(7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-1,2,3,5,6,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-7-one

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(2R,6R)-6-[(3S,5R,10S,12S,13R,14R,17R)-12-acetyloxy-3-hydroxy-4,4,10,13,14-pentamethyl-7,11,15-trioxo-1,2,3,5,6,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid

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octadeca-10,13-dienoic acid

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(E,2S)-6-[(5R,7S,10S,13R,14R,17R)-7-hydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxohept-5-enoic acid

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(10E,13E)-octadeca-10,13-dienoic acid

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ethyl octadeca-10,13-dienoate

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(2R,6R)-6-[(5R,10S,12S,13R,14R,17R)-12-acetyloxy-4,4,10,13,14-pentamethyl-3,7,11,15-tetraoxo-2,5,6,12,16,17-hexahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid

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ethyl (10E,13E)-octadeca-10,13-dienoate

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(2R,6R)-6-[(3S,5R,10S,13R,14R,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-7,11,15-trioxo-1,2,3,5,6,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid

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17-(7-hydroxy-6-methylhept-5-en-2-yl)-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-ol

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methyl (2R,6R)-6-[(3S,5R,10S,12S,13R,14R,17R)-12-acetyloxy-3-hydroxy-4,4,10,13,14-pentamethyl-7,11,15-trioxo-1,2,3,5,6,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoate

ergosterol endoperoxide

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(Z,6R)-6-[(5R,10S,13R,14R,15S,17R)-15-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-2-methylhept-2-enoic acid

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Ulrike Grienke

1

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Daniela Schuster

Daniela Schuster

3

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Gerhard Wolber

Gerhard Wolber

8

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Judith M Rollinger

Judith M Rollinger

12

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Hermann Stuppner

9

Hermann Stuppner

1 reference

9 August 2017

Judit Mihály-Bison

2

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9 August 2017

Taras Afonyushkin

4

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9 August 2017

Markus Binder

5

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9 August 2017

Shu-hong Guan

6

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9 August 2017

Chun-ru Cheng

7

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9 August 2017

De-an Guo

10

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9 August 2017

Valery N Bochkov

11

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Bioorganic & Medicinal Chemistry

9 August 2017

language of work or name

English

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publication date

November 2011

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16 September 2022

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9 August 2017

volume

19

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9 August 2017

issue

22

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9 August 2017

page(s)

6779-6791

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https://api.unpaywall.org/v2/10.1016/j.bmc.2011.09.039?email=unpaywall_01@example.com

9 August 2017

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19 March 2024

access restriction status

open access

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inferred from online access status

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25 September 2018

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Analysis of inflammatory gene induction by oxidized phospholipids in vivo by quantitative real-time RT-PCR in comparison with effects of LPS.

25 September 2018

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The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor

25 September 2018

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A natural product that lowers cholesterol as an antagonist ligand for FXR.

25 September 2018

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[Studies on the ganoderic acid, a new constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst]

25 September 2018

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Cytotoxic triterpenoids from Ganoderma lucidum

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12 December 2020

Analysis of triterpenoids in ganoderma lucidum using liquid chromatography coupled with electrospray ionization mass spectrometry

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Scalarane sesterterpenes from a marine sponge of the genus Spongia and their FXR antagonistic activity

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Identifiers

DOI

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9 August 2017

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9 August 2017

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