A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. (Q35664079)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

title

A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Daniele Bergamaschi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Andreas Schätzlein

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Kevin M Ryan

9

1 reference

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27 December 2019

8

Karen H Vousden

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

author name string

Helen S Bell

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Jim O'Prey

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Diane Crighton

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

Xin Lu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

language of work or name

English

0 references

publication date

8 March 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

27 December 2019

published in

1 reference

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27 December 2019

volume

117

1 reference

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27 December 2019

issue

4

1 reference

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27 December 2019

page(s)

1008-1018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts.

27 December 2019

cites work

1 reference

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DNA-binding independent cell death from a minimal proapoptotic region of E2F-1.

12 July 2018

1 reference

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Synthetic anticancer gene medicine exploits intrinsic antitumor activity of cationic vector to cure established tumors.

12 July 2018

1 reference

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Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells

12 July 2018

1 reference

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p53 mutation heterogeneity in cancer

12 July 2018

1 reference

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53BP2 induces apoptosis through the mitochondrial death pathway

12 July 2018

1 reference

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Relief of p53-mediated telomerase suppression by p73.

12 July 2018

1 reference

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The expression of iASPP in acute leukemias

12 July 2018

1 reference

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Splicing DNA-damage responses to tumour cell death.

12 July 2018

1 reference

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The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

ASPP1 and ASPP2: common activators of p53 family members

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

RETRACTED: p73alpha regulation by Chk1 in response to DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

The ASPP family: deciding between life and death after DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

TP53 family members and human cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

iASPP oncoprotein is a key inhibitor of p53 conserved from worm to human.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

The lower-generation polypropylenimine dendrimers are effective gene-transfer agents.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

p73: Friend or foe in tumorigenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Live or let die: the cell's response to p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Therapeutic exploitation of the p53 pathway

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Apoptosis: a link between cancer genetics and chemotherapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

p53, p63 and p73--solos, alliances and feuds among family members

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

On the shoulders of giants: p63, p73 and the rise of p53.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

ASPP proteins specifically stimulate the apoptotic function of p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

PUMA, a novel proapoptotic gene, is induced by p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

PUMA induces the rapid apoptosis of colorectal cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Evolution of functions within the p53/p63/p73 family.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

12 July 2018

Surfing the p53 network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Viral oncoproteins discriminate between p53 and the p53 homolog p73.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

A model for p53-induced apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Episomal vectors rapidly and stably produce high-titer recombinant retrovirus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

WAF1, a potential mediator of p53 tumor suppression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810568

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17347683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chemosensitivity linked to p73 function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17347683

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI28920

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17347683%20AND%20SRC:MED&resulttype=core&format=json

27 December 2019

1 reference