The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains. (Q35670468)

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17 February 2020

title

The Leukocyte Immunoglobulin-Like Receptor Family Member LILRB5 Binds to HLA-Class I Heavy Chains (English)

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17 February 2020

6

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17 February 2020

author name string

Zhiyong Zhang

1

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17 February 2020

Hiroko Hatano

2

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17 February 2020

Jacqueline Shaw

3

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17 February 2020

Marloes Olde Nordkamp

4

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17 February 2020

Guosheng Jiang

5

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17 February 2020

Simon Kollnberger

7

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17 February 2020

language of work or name

English

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publication date

22 June 2015

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17 February 2020

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17 February 2020

volume

10

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17 February 2020

issue

6

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17 February 2020

page(s)

e0129063

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Creative Commons Attribution 4.0 International

17 February 2020

copyright license

start time

22 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

A motif in LILRB2 critical for Angptl2 binding and activation.

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The arthritis-associated HLA-B*27:05 allele forms more cell surface B27 dimer and free heavy chain ligands for KIR3DL2 than HLA-B*27:09.

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KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis

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Inhibitory receptors bind ANGPTLs and support blood stem cells and leukaemia development

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HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I.

12 July 2018

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12 July 2018

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LILRA3 binds both classical and non-classical HLA class I molecules but with reduced affinities compared to LILRB1/LILRB2: structural evidence

12 July 2018

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Crystal Structure of Leukocyte Ig-like Receptor LILRB4 (ILT3/LIR-5/CD85k): A MYELOID INHIBITORY RECEPTOR INVOLVED IN IMMUNE TOLERANCE

12 July 2018

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HLA class I allelic sequence and conformation regulate leukocyte Ig-like receptor binding

12 July 2018

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The role of B27 heavy chain dimer immune receptor interactions in spondyloarthritis.

12 July 2018

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Differential expression of leukocyte immunoglobulin-like receptors on cord-blood-derived human mast cell progenitors and mature mast cells

12 July 2018

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Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation

12 July 2018

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Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d)

12 July 2018

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The LILR family: modulators of innate and adaptive immune pathways in health and disease.

12 July 2018

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Crystal structure of HLA-A2 bound to LIR-1, a host and viral major histocompatibility complex receptor

12 July 2018

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Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.

12 July 2018

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Leukocyte receptor complex-encoded immunomodulatory receptors show differing specificity for alternative HLA-B27 structures.

12 July 2018

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Cutting edge: HLA-B27 can form a novel beta 2-microglobulin-free heavy chain homodimer structure

12 July 2018

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The MHC class I binding proteins LIR-1 and LIR-2 inhibit Fc receptor-mediated signaling in monocytes

12 July 2018

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12 July 2018

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Human myelomonocytic cells express an inhibitory receptor for classical and nonclassical MHC class I molecules

12 July 2018

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HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom.

12 July 2018

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Secretion and cell surface expression of IgG1 are impaired in human B lymphoblasts that lack HLA-A, -B, and -C antigens

12 July 2018

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Alternative mRNA splicing creates transcripts encoding soluble proteins from most LILR genes.

12 July 2018

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Crystal structure of myeloid cell activating receptor leukocyte Ig-like receptor A2 (LILRA2/ILT1/LIR-7) domain swapped dimer: molecular basis for its non-binding to MHC complexes.

25 September 2018

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Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26098415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell-surface expression and immune receptor recognition of HLA-B27 homodimers

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26098415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0129063

1 reference

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17 February 2020

0 references

1 reference

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17 February 2020

PubMed publication ID

26098415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26098415%20AND%20SRC:MED&resulttype=core&format=json