The role of coactivators and corepressors in the biology and mechanism of action of steroid hormone receptors (Q35671179)

9 August 2017

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title

The role of coactivators and corepressors in the biology and mechanism of action of steroid hormone receptors (English)

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9 August 2017

Edwards DP

1

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9 August 2017

publication date

1 July 2000

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Journal of Mammary Gland Biology and Neoplasia

9 August 2017

published in

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9 August 2017

volume

5

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9 August 2017

issue

3

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9 August 2017

page(s)

307-324

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A canonical structure for the ligand-binding domain of nuclear receptors

9 August 2017

cites work

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12 December 2020

Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator

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12 December 2020

Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors

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12 December 2020

The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways

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12 December 2020

Expression and hormonal regulation of coactivator and corepressor genes

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12 December 2020

Interaction of steroid hormone receptors with the transcription initiation complex

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12 December 2020

Distinct classes of transcriptional activating domains function by different mechanisms

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12 December 2020

The RXR heterodimers and orphan receptors

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12 December 2020

The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT

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12 December 2020

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

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12 December 2020

Nuclear receptor coregulators: cellular and molecular biology

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12 December 2020

Coactivator and corepressor complexes in nuclear receptor function

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12 December 2020

Estrogen receptor activation function 1 works by binding p160 coactivator proteins

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12 December 2020

The human estrogen receptor has two independent nonacidic transcriptional activation functions

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12 December 2020

RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only weakly as a coactivator in cotransfection assays

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12 December 2020

An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens

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12 December 2020

Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor

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12 December 2020

Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase

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12 December 2020

Structural elements of an orphan nuclear receptor-DNA complex

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12 December 2020

Structural characterization of a minimal functional transactivation domain from the human glucocorticoid receptor

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12 December 2020

Expression of steroid receptor coactivator-1 mRNA in the developing mouse embryo: a possible role in olfactory epithelium development

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12 December 2020

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors

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12 December 2020

Steroid hormone receptors compete for factors that mediate their enhancer function

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12 December 2020

Different regions in activation function-1 of the human estrogen receptor required for antiestrogen- and estradiol-dependent transcription activation

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12 December 2020

Structural determinants of DNA-binding specificity by steroid receptors.

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12 December 2020

Functional interactions of the AF-2 activation domain core region of the human androgen receptor with the amino-terminal domain and with the transcriptional coactivator TIF2 (transcriptional intermediary factor2).

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12 December 2020

Structure and function of estrogen receptors.

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12 December 2020

Steroid receptor coactivator-1 is a histone acetyltransferase

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12 December 2020

Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

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12 December 2020

Steroid receptor interactions with heat shock protein and immunophilin chaperones

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12 December 2020

A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex

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12 December 2020

p300 stimulates transcription instigated by ligand-bound thyroid hormone receptor at a step subsequent to chromatin disruption

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12 December 2020

Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor

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12 December 2020

Differential recognition of target genes by nuclear receptor monomers, dimers, and heterodimers

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12 December 2020

Coregulatory proteins in steroid hormone receptor action: the role of chromatin high mobility group proteins HMG-1 and -2

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12 December 2020

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

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12 December 2020

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development

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12 December 2020

Multiple signal input and output domains of the 160-kilodalton nuclear receptor coactivator proteins

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12 December 2020

AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer

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12 December 2020

Hormone-dependent interaction between the amino- and carboxyl-terminal domains of progesterone receptor in vitro and in vivo.

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12 December 2020

The nuclear receptor superfamily: the second decade

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12 December 2020

Role of hydrophobic amino acid clusters in the transactivation activity of the human glucocorticoid receptor

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12 December 2020

Molecular basis of agonism and antagonism in the oestrogen receptor

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12 December 2020

In breast cancer, amplification of the steroid receptor coactivator gene AIB1 is correlated with estrogen and progesterone receptor positivity

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12 December 2020

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions

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12 December 2020

Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform

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12 December 2020

Histone-like TAFs within the PCAF histone acetylase complex

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12 December 2020

Acetylation of HMG I(Y) by CBP turns off IFN beta expression by disrupting the enhanceosome

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12 December 2020

Nuclear hormone receptor coregulators in action: diversity for shared tasks

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12 December 2020

Structure and specificity of nuclear receptor-coactivator interactions

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12 December 2020

Molecular mechanisms of action of steroid/thyroid receptor superfamily members

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12 December 2020

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

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12 December 2020

Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells

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12 December 2020

The N-terminal transactivation domain of rat estrogen receptor is localized in a hydrophobic domain of eighty amino acids

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12 December 2020

The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription

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12 December 2020

Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha

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12 December 2020

Coregulatory proteins in nuclear hormone receptor action

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12 December 2020

Structural studies of mutant glucocorticoid receptor transactivation domains establish a link between transactivation activity in vivo and alpha-helix-forming potential in vitro.

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12 December 2020

What's up and down with histone deacetylation and transcription?

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12 December 2020

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

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12 December 2020

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells

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12 December 2020

A limiting factor mediates the differential activation of promoters by the human progesterone receptor isoforms

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12 December 2020

Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen.

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12 December 2020

Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain

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12 December 2020

Targeting chromatin disruption: Transcription regulators that acetylate histones

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12 December 2020

The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor

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12 December 2020

RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2

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12 December 2020

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

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12 December 2020

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors

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12 December 2020

Regulation of transcription by a protein methyltransferase

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12 December 2020

The linkage of Kennedy's neuron disease to ARA24, the first identified androgen receptor polyglutamine region-associated coactivator

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12 December 2020

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

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12 December 2020

The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors.

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12 December 2020

Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300

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12 December 2020

Transcriptional control. Sinful repression

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12 December 2020

Orphan nuclear receptors: from gene to function

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12 December 2020

Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone

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12 December 2020

The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

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12 December 2020

Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities

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12 December 2020

Increasing the complexity of coactivation in nuclear receptor signaling

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12 December 2020

Interaction of the glucocorticoid receptor DNA-binding domain with DNA as a dimer is mediated by a short segment of five amino acids

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12 December 2020

High-mobility group chromatin proteins 1 and 2 functionally interact with steroid hormone receptors to enhance their DNA binding in vitro and transcriptional activity in mammalian cells

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12 December 2020

Anatomy of the Steroid Receptor Zinc Finger Region

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12 December 2020

The histone acetylase PCAF is a nuclear receptor coactivator.

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12 December 2020

Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems

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12 December 2020

p300 is a component of an estrogen receptor coactivator complex

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12 December 2020

Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin

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12 December 2020

Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors

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12 December 2020

p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation

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12 December 2020

TRAM-1, A novel 160-kDa thyroid hormone receptor activator molecule, exhibits distinct properties from steroid receptor coactivator-1

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12 December 2020

Special HATs for special occasions: linking histone acetylation to chromatin assembly and gene activation

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12 December 2020

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

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12 December 2020

Ligand-dependent, transcriptionally productive association of the amino- and carboxyl-terminal regions of a steroid hormone nuclear receptor

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12 December 2020

AF-2 activity and recruitment of steroid receptor coactivator 1 to the estrogen receptor depend on a lysine residue conserved in nuclear receptors

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12 December 2020

A novel fusion between MOZ and the nuclear receptor coactivator TIF2 in acute myeloid leukemia

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12 December 2020

Transcription factor-specific requirements for coactivators and their acetyltransferase functions

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12 December 2020

Nuclear protein CBP is a coactivator for the transcription factor CREB

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12 December 2020

Interaction between the amino- and carboxyl-terminal regions of the rat androgen receptor modulates transcriptional activity and is influenced by nuclear receptor coactivators.

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12 December 2020

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene

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12 December 2020

Estrogen receptor interaction with co-activators and co-repressors

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12 December 2020

Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium

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12 December 2020

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes

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12 December 2020

GRIP1, a transcriptional coactivator for the AF-2 transactivation domain of steroid, thyroid, retinoid, and vitamin D receptors

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12 December 2020

Interaction of the Putative Androgen Receptor-Specific Coactivator ARA70/ELE1α with Multiple Steroid Receptors and Identification of an Internally Deleted ELE1β Isoform

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12 December 2020

Identifiers

DOI

10.1023/A:1009503029176

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Dimensions Publication ID

9 August 2017

1015012077

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