MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis (Q35672212)

9 August 2017

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis (English)

1 reference

9 August 2017

1 reference

Ling-Zhi Liu

2

0 references

Bing-Hua Jiang

object named as

Bing-Hua Jiang

8

0 references

author name string

Qing Xu

1

1 reference

9 August 2017

Xu Qian

3

1 reference

9 August 2017

Qi Chen

4

1 reference

9 August 2017

Yue Jiang

5

1 reference

9 August 2017

Dan Li

6

1 reference

9 August 2017

Lihui Lai

7

1 reference

9 August 2017

language of work or name

English

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publication date

14 September 2011

1 reference

9 August 2017

Nucleic Acids Research

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9 August 2017

40

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9 August 2017

761-774

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9 August 2017

2

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

9 August 2017

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3258133/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

MiR-145 inhibits cell proliferation of human lung adenocarcinoma by targeting EGFR and NUDT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

miRNA-145 inhibits non-small cell lung cancer cell proliferation by targeting c-Myc

12 July 2018

1 reference

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miR-145-dependent targeting of junctional adhesion molecule A and modulation of fascin expression are associated with reduced breast cancer cell motility and invasiveness

12 July 2018

1 reference

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Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene Friend leukemia virus integration 1 gene

12 July 2018

1 reference

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MiR-145, a new regulator of the DNA fragmentation factor-45 (DFF45)-mediated apoptotic network

12 July 2018

1 reference

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miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

MicroRNA-145 targets YES and STAT1 in colon cancer cells

12 July 2018

1 reference

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MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1

12 July 2018

1 reference

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Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

12 July 2018

1 reference

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The microRNA network and tumor metastasis

12 July 2018

1 reference

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Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1

12 July 2018

1 reference

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miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors

12 July 2018

1 reference

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Characterization of global microRNA expression reveals oncogenic potential of miR-145 in metastatic colorectal cancer

12 July 2018

1 reference

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miR-145 directs intestinal maturation in zebrafish

12 July 2018

1 reference

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miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells

12 July 2018

1 reference

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MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

12 July 2018

1 reference

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Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma

12 July 2018

1 reference

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Modulation of microRNA processing by p53

12 July 2018

1 reference

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miR-145 and miR-143 regulate smooth muscle cell fate and plasticity

12 July 2018

1 reference

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MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

12 July 2018

1 reference

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MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

12 July 2018

1 reference

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miR-145 inhibits breast cancer cell growth through RTKN.

12 July 2018

1 reference

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MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma

12 July 2018

1 reference

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Uncovering growth-suppressive MicroRNAs in lung cancer

12 July 2018

1 reference

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p53 represses c-Myc through induction of the tumor suppressor miR-145

12 July 2018

1 reference

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mTOR pathway and mTOR inhibitors as agents for cancer therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Diagnostic and prognostic microRNAs in stage II colon cancer.

12 July 2018

1 reference

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Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment

12 July 2018

1 reference

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Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion

12 July 2018

1 reference

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12 July 2018

Cancer statistics, 2008

1 reference

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Suppression of programmed cell death 4 (PDCD4) protein expression by BCR-ABL-regulated engagement of the mTOR/p70 S6 kinase pathway

12 July 2018

1 reference

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Altered expression of miR-21, miR-31, miR-143 and miR-145 is related to clinicopathologic features of colorectal cancer

12 July 2018

1 reference

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MicroRNA signatures in human ovarian cancer

12 July 2018

1 reference

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Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

12 July 2018

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Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

MicroRNA gene expression deregulation in human breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Apigenin inhibits expression of vascular endothelial growth factor and angiogenesis in human lung cancer cells: implication of chemoprevention of lung cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

The TOR pathway: a target for cancer therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Reduced accumulation of specific microRNAs in colorectal neoplasia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

microRNAs: tiny regulators with great potential

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

An extensive class of small RNAs in Caenorhabditis elegans

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Tumor angiogenesis: therapeutic implications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Vascular endothelial growth factor is a secreted angiogenic mitogen

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Decreased expression of microRNA-143 and -145 in human gastric cancers.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Identification of novel microRNA targets based on microRNA signatures in bladder cancer

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Activation of Akt-mTOR-p70S6K pathway in angiogenesis in hepatocellular carcinoma.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3258133

Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1α expression through activation of AKT and P70S6K1 in human ovarian cancer cells

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21917858

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKR730

1 reference

9 August 2017

1 reference

9 August 2017

1 reference