Is nose-to-brain transport of drugs in man a reality? (Q35673938)

9 August 2017

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title

Is nose-to-brain transport of drugs in man a reality? (English)

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9 August 2017

Lisbeth Illum

1

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9 August 2017

1 January 2004

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Journal of Pharmacy and Pharmacology

9 August 2017

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9 August 2017

56

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9 August 2017

1

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9 August 2017

3-17

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Transneuronal transport of peroxidase-conjugated wheat germ agglutinin (WGA-HRP) from the olfactory epithelium to the brain of the adult rat.

9 August 2017

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Nasal delivery of [14C]dextromethorphan hydrochloride in rats: levels in plasma and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Direct transport of cocaine from the nasal cavity to the brain following intranasal cocaine administration in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Direct nose-brain transport of benzoylecgonine following intranasal administration in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Levels of dopamine in blood and brain following nasal administration to rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Intranasal angiotensin II directly influences central nervous regulation of blood pressure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

The olfactory and respiratory epithelium in rhesus and squirrel monkeys studied with freeze-fracture technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Manipulating neuropeptidergic pathways in humans: a novel approach to neuropharmacology?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

How the olfactory system makes sense of scents

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Neuroprotective strategy for Alzheimer disease: intranasal administration of a fatty neuropeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

P-Glycoprotein attenuates brain uptake of substrates after nasal instillation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Nasal delivery. The use of animal models to predict performance in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Transport of drugs from the nasal cavity to the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Nasal drug delivery--possibilities, problems and solutions

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Anterograde transsynaptic transport of WGA-HRP in rat olfactory pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

The nose and paranasal sinuses physiology and anatomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Evidence for central nervous effects of corticotropin-releasing hormone on gastric acid secretion in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Central nervous system effects of intranasally administered insulin during euglycemia in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Improving influence of insulin on cognitive functions in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Uptake of exogenous proteins in mouse olfactory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Electroencephalographic effects and serum concentrations after intranasal and intravenous administration of diazepam to healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Nasal route for direct delivery of solutes to the central nervous system: fact or fiction?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Direct access of drugs to the human brain after intranasal drug administration?

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

The fine structure of the olfactory mucosa in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Morphology of olfactory epithelium in humans and other vertebrates

21 January 2018

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https://api.crossref.org/works/10.1211%2F0022357022539

Extracellular space structure revealed by diffusion analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

The first attempt at radioisotopic evaluation of the integrity of the nose-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Sleep and endocrine changes after intranasal administration of growth hormone-releasing hormone in young and aged humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Beneficial treatment of age-related sleep disturbances with prolonged intranasal vasopressin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Brain potential changes after intranasal vs. intravenous administration of vasopressin: evidence for a direct nose-brain pathway for peptide effects in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

A nose-brain pathway for psychotropic peptides: evidence from a brain evoked potential study with cholecystokinin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Time course of intranasally administered cholecystokinin-8 on central nervous effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Transport of cephalexin to the cerebrospinal fluid directly from the nasal cavity

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Transport of molecules from nose to brain: transneuronal anterograde and retrograde labeling in the rat olfactory system by wheat germ agglutinin-horseradish peroxidase applied to the nasal epithelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Brain potentials and attention after acute and subchronic intranasal administration ofACTH 4-10 and desacetyl-alpha-MSH in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

The epithelial tight junction: structure, function and preliminary biochemical characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Delivery of neurotrophic factors to the central nervous system: pharmacokinetic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Nasal absorption of hydroxocobalamin in healthy elderly adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

Brain uptake of dihydroergotamine after intravenous and nasal administration in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1211%2F0022357022539

21 January 2018

Identifiers

DOI

10.1211/0022357022539

1 reference

9 August 2017

1 reference

PubMed ID

14979996