Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism. (Q35681058)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Wnt6, Wnt10a and Wnt10b inhibit adipogenesis and stimulate osteoblastogenesis through a β-catenin-dependent mechanism (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

1

1 reference

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11 February 2020

Ormond Macdougald

7

1 reference

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11 February 2020

author name string

Adam J Bree

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Yao Yao

3

1 reference

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11 February 2020

Baowen Du

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Nahid Hemati

5

1 reference

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11 February 2020

Gabriel Martinez-Santibañez

6

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11 February 2020

publication date

18 August 2011

1 reference

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11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

50

1 reference

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11 February 2020

issue

2

1 reference

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11 February 2020

page(s)

477-489

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

TLE3 is a dual-function transcriptional coregulator of adipogenesis

11 February 2020

cites work

1 reference

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A functional promoter polymorphism -607G>C of WNT10B is associated with abdominal fat in Korean female subjects

27 July 2018

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Propagation of adipogenic signals through an epigenomic transition state.

27 July 2018

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Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node

27 July 2018

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27 July 2018

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Wnt5b stimulates adipogenesis by activating PPARgamma, and inhibiting the beta-catenin dependent Wnt signaling pathway together with Wnt5a

27 July 2018

1 reference

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COUP-TFII acts downstream of Wnt/beta-catenin signal to silence PPARgamma gene expression and repress adipogenesis.

27 July 2018

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Association analysis of WNT10B with bone mass and structure among individuals of African ancestry

27 July 2018

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Inhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiation

27 July 2018

1 reference

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The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis

27 July 2018

1 reference

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Wnt10b increases postnatal bone formation by enhancing osteoblast differentiation

27 July 2018

1 reference

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Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway.

27 July 2018

1 reference

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WNT10B mutations in human obesity.

27 July 2018

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Importance of quantitative PCR primer location for short interfering RNA efficacy determination

27 July 2018

1 reference

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Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin

27 July 2018

1 reference

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Wnt/beta-catenin signaling in mesenchymal progenitors controls osteoblast and chondrocyte differentiation during vertebrate skeletogenesis

27 July 2018

1 reference

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Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Wnt signaling inhibits adipogenesis through beta-catenin-dependent and -independent mechanisms.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Essential role of beta-catenin in postnatal bone acquisition

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Wnt5b partially inhibits canonical Wnt/beta-catenin signaling pathway and promotes adipogenesis in 3T3-L1 preadipocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Regulation of osteoblastogenesis and bone mass by Wnt10b

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Sequential roles of Hedgehog and Wnt signaling in osteoblast development

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Association of the gene encoding wingless-type mammary tumor virus integration-site family member 5B (WNT5B) with type 2 diabetes

27 July 2018

1 reference

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Wnt-4 activates the canonical beta-catenin-mediated Wnt pathway and binds Frizzled-6 CRD: functional implications of Wnt/beta-catenin activity in kidney epithelial cells

27 July 2018

1 reference

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A twist code determines the onset of osteoblast differentiation

27 July 2018

1 reference

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Differential roles of insulin receptor substrates in brown adipocyte differentiation

27 July 2018

1 reference

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Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis.

27 July 2018

1 reference

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Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent beta-catenin degradation

27 July 2018

1 reference

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The TAK1-NLK mitogen-activated protein kinase cascade functions in the Wnt-5a/Ca(2+) pathway to antagonize Wnt/beta-catenin signaling

27 July 2018

1 reference

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Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors

27 July 2018

1 reference

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Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism

27 July 2018

1 reference

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Regulation of Wnt signaling during adipogenesis

27 July 2018

1 reference

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p300 coactivates the adipogenic transcription factor CCAAT/enhancer-binding protein alpha

27 July 2018

1 reference

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Inhibition of adipogenesis by Wnt signaling

27 July 2018

1 reference

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Alkaline phosphatase knock-out mice recapitulate the metabolic and skeletal defects of infantile hypophosphatasia

27 July 2018

1 reference

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Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARgamma2.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Product differentiation by analysis of DNA melting curves during the polymerase chain reaction

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Polymorphisms of the WNT10B gene, bone mineral density, and fractures in postmenopausal women.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Dact1, a nutritionally regulated preadipocyte gene, controls adipogenesis by coordinating the Wnt/beta-catenin signaling network

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Wnt4 and Wnt5a promote adipocyte differentiation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Wnt10b inhibits obesity in ob/ob and agouti mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Adipocyte differentiation from the inside out

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Effects of Wnt signaling on brown adipocyte differentiation and metabolism mediated by PGC-1alpha

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Wnt10b inhibits development of white and brown adipose tissues

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Inactivation of two mouse alkaline phosphatase genes and establishment of a model of infantile hypophosphatasia.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261372

Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21872687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wnt signaling stimulates osteoblastogenesis of mesenchymal precursors by suppressing CCAAT/enhancer-binding protein alpha and peroxisome proliferator-activated receptor gamma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21872687

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BONE.2011.08.010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21872687%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference