Genes associated with addiction: alcoholism, opiate, and cocaine addiction (Q35682961)

9 August 2017

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title

Genes associated with addiction: alcoholism, opiate, and cocaine addiction (English)

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9 August 2017

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1

Mary Jeanne Kreek

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9 August 2017

David A Nielsen

2

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9 August 2017

K Steven LaForge

series ordinal

3

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9 August 2017

publication date

1 January 2004

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9 August 2017

published in

NeuroMolecular Medicine

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9 August 2017

volume

5

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9 August 2017

issue

1

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9 August 2017

page(s)

85-108

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Quantitative trait loci mapping of three loci controlling morphine preference using inbred mouse strains.

9 August 2017

cites work

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12 December 2020

Characterization of the three genotypes of low Km aldehyde dehydrogenase in a Japanese population

1 reference

12 December 2020

The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine

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12 December 2020

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction

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12 December 2020

Genetic factors in alcohol metabolism and alcoholism

1 reference

12 December 2020

Alcohol and aldehyde dehydrogenase genotypes and drinking behavior in Japanese

1 reference

12 December 2020

Genetics of two mu opioid receptor gene (OPRM1) exon I polymorphisms: population studies, and allele frequencies in alcohol- and drug-dependent subjects

1 reference

12 December 2020

Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism

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12 December 2020

Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant

1 reference

12 December 2020

The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression

1 reference

12 December 2020

The human mu opioid receptor gene: 5' regulatory and intronic sequences

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12 December 2020

Meta-analysis of the effects of alcohol dehydrogenase genotype on alcohol dependence and alcoholic liver disease

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12 December 2020

Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese Han.

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12 December 2020

Possible protective role against alcoholism for aldehyde dehydrogenase isozyme deficiency in Japan

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12 December 2020

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

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12 December 2020

Functional variation in promoter region of monoamine oxidase A and subtypes of alcoholism: haplotype analysis

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12 December 2020

Alcohol elimination in Native American Mission Indians: an investigation of interindividual variation.

1 reference

12 December 2020

Effect of chronic “binge cocaine” on basal levels and cocaine‐induced increases of dopamine in the caudate putamen and nucleus accumbens of C57BL/6J and 129/J mice

1 reference

12 December 2020

Polymorphism of ADH and ALDH genes among four ethnic groups in China and effects upon the risk for alcoholism

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12 December 2020

Murine chromosomal location of the mu and kappa opioid receptor genes

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12 December 2020

Human mu opioid receptor gene polymorphisms and vulnerability to substance abuse.

1 reference

12 December 2020

Excess dopamine D4 receptor (D4DR) exon III seven repeat allele in opioid-dependent subjects

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12 December 2020

Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

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12 December 2020

International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function

1 reference

12 December 2020

Blockade of central neuropeptide Y (NPY) Y2 receptors reduces ethanol self-administration in rats.

1 reference

12 December 2020

Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms

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12 December 2020

Catechol O -methyltransferase val 158 -met genotype and individual variation in the brain response to amphetamine

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12 December 2020

Association analysis of polymorphisms in the μ opioid gene and heroin abuse in Chinese subjects.

1 reference

12 December 2020

Nomenclature for human CYP2D6 alleles

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12 December 2020

Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene

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12 December 2020

Association between the functional variant of the catechol-O-methyltransferase (COMT) gene and type 1 alcoholism.

1 reference

12 December 2020

A quantitative-trait analysis of human plasma-dopamine beta-hydroxylase activity: evidence for a major functional polymorphism at the DBH locus

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12 December 2020

The collaborative study on the genetics of alcoholism: an update.

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12 December 2020

Single nucleotide polymorphisms in the human mu opioid receptor gene alter basal G protein coupling and calmodulin binding

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12 December 2020

Multipoint linkage analysis using the weighted-pairwise correlation statistic

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12 December 2020

A genome-wide search for quantitative trait loci influencing substance dependence vulnerability in adolescence

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12 December 2020

Concentrations of monoamine metabolites in the cerebrospinal fluid of twins and unrelated individuals--a genetic study

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12 December 2020

Codeine increases pain thresholds to copper vapor laser stimuli in extensive but not poor metabolizers of sparteine.

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12 December 2020

Alcohol-Metabolising Genes and Alcoholism Among Taiwanese Han Men: Independent Effect of ADH2, ADH3 and ALDH2

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12 December 2020

Linkage of Antisocial Alcoholism to the Serotonin 5-HT1B Receptor Gene in 2 Populations

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12 December 2020

Association between mu opioid receptor gene polymorphisms and Chinese heroin addicts

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12 December 2020

Familial Transmission of Substance Use Disorders

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12 December 2020

Mu opioid receptor gene polymorphisms and heroin dependence in Asian populations

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12 December 2020

DRD4 exon III VNTR polymorphism—susceptibility factor for heroin dependence? Results of a case-control and a family-based association approach

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12 December 2020

Association of neuropeptide y polymorphism with the occurrence of type 1 and type 2 alcoholism

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12 December 2020

Treatment of codeine dependence with inhibitors of cytochrome P450 2D6

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12 December 2020

Mu opioid receptor gene variants: lack of association with alcohol dependence

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12 December 2020

Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants

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12 December 2020

Potentially functional polymorphism in the promoter region of prodynorphin gene may be associated with protection against cocaine dependence or abuse

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12 December 2020

The role of GABA(A) receptors in the acute and chronic effects of ethanol

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12 December 2020

Association analysis of the dopamine D4 gene exon III VNTR and heroin abuse in Chinese subjects

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12 December 2020

A missense mutation in human fatty acid amide hydrolase associated with problem drug use.

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12 December 2020

Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities

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12 December 2020

Sequence variations in the mu-opioid receptor gene (OPRM1) associated with human addiction to heroin

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12 December 2020

Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping

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12 December 2020

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA

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12 December 2020

Pharmacotherapy of addictions

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12 December 2020

Neuropeptide Y and its receptors as potential therapeutic drug targets

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12 December 2020

Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1).

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12 December 2020

The mu-opioid receptor gene polymorphism (A118G) alters HPA axis activation induced by opioid receptor blockade

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12 December 2020

Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication.

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12 December 2020

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men

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12 December 2020

A tryptophan hydroxylase gene marker for suicidality and alcoholism.

1 reference

12 December 2020

Chromosome Mapping of Gene Loci Affecting Morphine and Amphetamine Responses in BXD Recombinant Inbred Mice

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12 December 2020

Alcohol sensitivity related to polymorphism of alcohol-metabolizing enzymes in Japanese

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12 December 2020

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12 December 2020

Polymorphisms of the D4 dopamine receptor alleles in chronic alcoholism.

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12 December 2020

The 5' region of the tryptophan hydroxylase gene: mutation search and association study with alcoholism.

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12 December 2020

The relationship between low Km aldehyde dehydrogenase phenotype and drinking behavior in Japanese

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12 December 2020

Inhibition of cytochrome P450 2D6 modifies codeine abuse liability

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12 December 2020

Linkage of a gene regulating dopamine-beta-hydroxylase activity and the ABO blood group locus

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12 December 2020

Isolation and characterization of aldehyde dehydrogenase isozymes from usual and atypical human livers

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12 December 2020

No heroin or morphine 6beta-glucuronide analgesia in mu-opioid receptor knockout mice

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12 December 2020

A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances

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12 December 2020

Tryptophan hydroxylase immunoreactivity is altered by the genetic variation in postmortem brain samples of both suicide victims and controls

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12 December 2020

Nonreplication of association between mu-opioid-receptor gene (OPRM1) A118G polymorphism and substance dependence

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12 December 2020

Opioid receptors: some perspectives from early studies of their role in normal physiology, stress responsivity, and in specific addictive diseases

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12 December 2020

Ethanol consumption and resistance are inversely related to neuropeptide Y levels

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12 December 2020

Genetically deficient CYP2D6 metabolism provides protection against oral opiate dependence.

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12 December 2020

Association study of alcoholism subtypes with a functional promoter polymorphism in the serotonin transporter protein gene

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12 December 2020

Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A

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12 December 2020

Genetics of red cell COMT activity: Analysis of thermal stability and family data

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12 December 2020

Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia

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12 December 2020

Association of monoamine oxidase A alleles with alcoholism among male Chinese in Taiwan.

1 reference

12 December 2020

Specificity of genetic and environmental risk factors for use and abuse/dependence of cannabis, cocaine, hallucinogens, sedatives, stimulants, and opiates in male twins

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12 December 2020

Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles.

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12 December 2020

Suicidality and 5-Hydroxyindoleacetic Acid Concentration Associated With a Tryptophan Hydroxylase Polymorphism

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12 December 2020

Association analysis of exonic variants of the gene encoding the GABAB receptor and alcohol dependence.

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12 December 2020

A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States

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12 December 2020

Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in Orientals

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12 December 2020

Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

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12 December 2020

An allelic variation in the human prodynorphin gene promoter alters stimulus-induced expression

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12 December 2020

D4 dopamine-receptor (DRD4) alleles and novelty seeking in substance-dependent, personality-disorder, and control subjects

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12 December 2020

Possible control of dopamine beta-hydroxylase via a codominant mechanism associated with the polymorphic (GT)n repeat at its gene locus in healthy individuals

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12 December 2020

Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an American Indian population.

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12 December 2020

Morphine self-administration in mu-opioid receptor-deficient mice

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12 December 2020

Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers

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12 December 2020

Nalmefene causes greater hypothalamic-pituitary-adrenal axis activation than naloxone in normal volunteers: implications for the treatment of alcoholism

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12 December 2020

Inheritance of low erythrocyte catechol-o-methyltransferase activity in man

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12 December 2020

Genome-wide search for genes affecting the risk for alcohol dependence

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12 December 2020

Identification of the primary gene defect at the cytochrome P450 CYP2D locus

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12 December 2020

Neuropeptide Y polymorphism and alcohol consumption in middle-aged men

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12 December 2020

Association of a regulatory polymorphism in the promoter region of the monoamine oxidase A gene with antisocial alcoholism

1 reference

12 December 2020

Use of drugs, alcohol and tobacco by people with schizophrenia: case-control study

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12 December 2020

Association between the functional polymorphism of catechol-O-methyltransferase gene and alcohol consumption among social drinkers

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12 December 2020

Further evidence for a quantitative trait locus on murine chromosome 10 controlling morphine preference in inbred mice

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12 December 2020

The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome

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12 December 2020

Alcohol sensitivity, alcohol metabolism, risk of alcoholism, and the role of alcohol and aldehyde dehydrogenase genotypes.

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12 December 2020

Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation

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12 December 2020

Cytochrome P450 2D6 and treatment of codeine dependence.

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12 December 2020

Preliminary evidence for an association of a dinucleotide repeat polymorphism at the MAOA gene with early onset alcoholism/substance abuse

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12 December 2020

A haplotype at the DBH locus, associated with low plasma dopamine beta-hydroxylase activity, also associates with cocaine-induced paranoia

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12 December 2020

Bidirectional effects of GABAergic agonists and antagonists on maintenance of voluntary ethanol intake in rats

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12 December 2020

Genetics of alcohol and tobacco use in humans.

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12 December 2020

A combination of mutations in the CYP2D6*17 (CYP2D6Z) allele causes alterations in enzyme function.

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12 December 2020

Association between alcoholism and the dopamine D4 receptor gene

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12 December 2020

Isolation and structural organization of the human preproenkephalin B gene

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12 December 2020

Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency

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12 December 2020

Characteristics of Japanese alcoholics with the atypical aldehyde dehydrogenase 2*2. I. A comparison of the genotypes of ALDH2, ADH2, ADH3, and cytochrome P-4502E1 between alcoholics and nonalcoholics

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12 December 2020

Influence of ADH1B polymorphism on alcohol use and its subjective effects in a Jewish population

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12 December 2020

A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients

1 reference

12 December 2020

Codeine and morphine in extensive and poor metabolizers of sparteine: pharmacokinetics, analgesic effect and side effects

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12 December 2020

Catechol-O-methyltransferase Val-108/158-Met gene variants associated with performance on the Wisconsin Card Sorting Test

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12 December 2020

Identification of a novel polymorphism of the human dopamine transporter (DAT1) gene and the significant association with alcoholism

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12 December 2020

Association of the ADH2*3 allele with a negative family history of alcoholism in African American young adults

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12 December 2020

Opioid receptor and peptide gene polymorphisms: potential implications for addictions

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12 December 2020

Human chromosomes 11p15 and 4p12 and alcohol dependence: possible association with the GABRB1 gene

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12 December 2020

mu-Opioid receptor knockout mice do not self-administer alcohol

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12 December 2020

Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence

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12 December 2020

Association between novelty seeking and the type 4 dopamine receptor gene in a large Finnish cohort sample

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12 December 2020

Association between a functional catechol O-methyltransferase gene polymorphism and schizophrenia: meta-analysis of case-control and family-based studies

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12 December 2020

NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations

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12 December 2020

A single nucleotide polymorphic mutation in the human mu-opioid receptor severely impairs receptor signaling

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12 December 2020

Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders

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12 December 2020

ADH2 and alcohol-related phenotypes in Ashkenazic Jewish American college students.

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12 December 2020

Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors

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12 December 2020

Genetics of human alcohol-metabolizing enzymes

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12 December 2020

5-HT2A receptor gene polymorphism is associated with food and alcohol intake in obese people

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12 December 2020

The HTR1B 861G>C receptor polymorphism among patients suffering from alcoholism, major depression, anxiety disorders and narcolepsy

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12 December 2020

Protective association of genetic variation in alcohol dehydrogenase with alcohol dependence in Native American Mission Indians.

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12 December 2020

Reduced aggression in mice lacking the serotonin transporter

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12 December 2020

Relationship of psychopathology to the human serotonin1B genotype and receptor binding kinetics in postmortem brain tissue

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12 December 2020

Association of a leucine(7)-to-proline(7) polymorphism in the signal peptide of neuropeptide Y with high serum cholesterol and LDL cholesterol levels

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12 December 2020

Quick onset of severe abdominal pain after codeine in an ultrarapid metabolizer of debrisoquine

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12 December 2020

Association of the ADH2*3 allele with greater alcohol expectancies in African-American young adults

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12 December 2020

Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice

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12 December 2020

Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes

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12 December 2020

Dopamine transporter gene polymorphism and alcoholism

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12 December 2020

Allelic variation S268P of the human mu-opioid receptor affects both desensitization and G protein coupling.

1 reference

12 December 2020

A functional polymorphism in the monoamine oxidase A gene promoter

1 reference

12 December 2020

Familial transmission of substance dependence: alcohol, marijuana, cocaine, and habitual smoking: a report from the Collaborative Study on the Genetics of Alcoholism.

1 reference

12 December 2020

Inheritance of alcohol abuse. Cross-fostering analysis of adopted men

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12 December 2020

The DRD4 VNTR polymorphism moderates craving after alcohol consumption

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12 December 2020

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

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12 December 2020

Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism

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12 December 2020

Studies of the 48 bp repeat polymorphism of the DRD4 gene in impulsive, compulsive, addictive behaviors: Tourette syndrome, ADHD, pathological gambling, and substance abuse

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12 December 2020

Serum dopamine beta-hydroxylase

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12 December 2020

Allelic association of tryptophan hydroxylase with alcoholism in five Taiwanese ethnic groups

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12 December 2020

Naltrexone decreases craving and alcohol self-administration in alcohol-dependent subjects and activates the hypothalamo-pituitary-adrenocortical axis.

1 reference

12 December 2020

Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine

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12 December 2020

Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism

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12 December 2020

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

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12 December 2020

Rewarding effects of ethanol and cocaine in mu opioid receptor-deficient mice

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12 December 2020

Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism

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12 December 2020

Multiple dopamine D4 receptor variants in the human population

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12 December 2020

Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach

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12 December 2020

Identifiers

DOI

10.1385/NMM:5:1:085

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Dimensions Publication ID

9 August 2017

1009764378

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Fatcat ID

release_wlgdmzheaveznfpdn3iyv5acxm

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Fatcat

https://api.fatcat.wiki/v0/release/wlgdmzheaveznfpdn3iyv5acxm

24 November 2022

mapped directly with Wikidata item

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