Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8 (Q35683004)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21920918%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8 (English)

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12 February 2020

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heritable pulmonary arterial hypertension

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1

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12 February 2020

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Suzy A Comhair

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12 February 2020

author name string

Deborah Zygmunt

2

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12 February 2020

Lori Mavrakis

3

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12 February 2020

Phyllis Harbor

4

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12 February 2020

Lingli Wang

5

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12 February 2020

Serpil C Erzurum

7

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12 February 2020

Micheala A Aldred

8

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12 February 2020

language of work or name

English

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publication date

15 September 2011

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American Journal of Respiratory and Critical Care Medicine

12 February 2020

published in

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12 February 2020

volume

184

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12 February 2020

issue

12

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page(s)

1400-1408

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Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

12 February 2020

cites work

1 reference

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miR-21 mediates fibrogenic activation of pulmonary fibroblasts and lung fibrosis

12 July 2018

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Somatic chromosome abnormalities in the lungs of patients with pulmonary arterial hypertension

12 July 2018

1 reference

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Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline

12 July 2018

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TGFbeta-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3.

12 July 2018

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miR-21 as a key regulator of oncogenic processes

12 July 2018

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Updated clinical classification of pulmonary hypertension.

12 July 2018

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Defective pulmonary vascular remodeling in Smad8 mutant mice

12 July 2018

1 reference

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Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells

12 July 2018

1 reference

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A new nonsense mutation of SMAD8 associated with pulmonary arterial hypertension

12 July 2018

1 reference

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Penetrance of pulmonary arterial hypertension is modulated by the expression of normal BMPR2 allele

12 July 2018

1 reference

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miR-21: a small multi-faceted RNA.

12 July 2018

1 reference

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High levels of hyaluronan in idiopathic pulmonary arterial hypertension

12 July 2018

1 reference

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SMAD proteins control DROSHA-mediated microRNA maturation

12 July 2018

1 reference

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Functional redundancy of TGF-beta family type I receptors and receptor-Smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse

12 July 2018

1 reference

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Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension

12 July 2018

1 reference

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Alterations of cellular bioenergetics in pulmonary artery endothelial cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262031

Downregulation of type II bone morphogenetic protein receptor in hypoxic pulmonary hypertension

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262031

Targeted mutagenesis of Smad1 reveals an essential role in chorioallantoic fusion

12 July 2018

1 reference

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Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.

12 July 2018

1 reference

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Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

12 July 2018

1 reference

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Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects.

12 July 2018

1 reference

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Mutations in the SMAD4/DPC4 gene in juvenile polyposis

12 July 2018

1 reference

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Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension.

12 July 2018

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Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood

21 January 2018

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Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

21 January 2018

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Smad signaling in the rat model of monocrotaline pulmonary hypertension

21 January 2018

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Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease

21 January 2018

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Activation of the bone morphogenetic protein receptor by H11kinase/Hsp22 promotes cardiac cell growth and survival.

21 January 2018

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Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

21 January 2018

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BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension

21 January 2018

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Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

21 January 2018

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Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension

21 January 2018

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Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation

21 January 2018

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12 December 2020

Dysregulated Bone Morphogenetic Protein Signaling in Monocrotaline-Induced Pulmonary Arterial Hypertension

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12 December 2020

Hyperproliferative apoptosis-resistant endothelial cells in idiopathic pulmonary arterial hypertension

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12 December 2020

Early-life pulmonary arterial hypertension with subsequent development of diffuse pulmonary arteriovenous malformations in hereditary haemorrhagic telangiectasia type 1

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12 December 2020

10.1164/RCCM.201106-1130OC

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21920918%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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12 February 2020

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