Benefit-risk assessment of long-acting beta2-agonists in asthma (Q35683221)

9 August 2017

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title

Benefit-risk assessment of long-acting beta2-agonists in asthma (English)

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9 August 2017

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Catherine M Jackson

1

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PubMed ID

15003036

9 August 2017

Brian Lipworth

series ordinal

2

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9 August 2017

1 January 2004

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9 August 2017

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9 August 2017

27

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9 August 2017

4

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9 August 2017

243-270

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https://scigraph.springernature.com/pub.10.2165/00002018-200427040-00003

9 August 2017

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Systemic effects of formoterol and salmeterol: a dose-response comparison in healthy subjects

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Salmeterol does not compromise the bronchodilator response to albuterol during acute episodes of asthma

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Effects of treatment with formoterol on bronchoprotection against methacholine

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Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease

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Concomitant administration of low-dose prednisolone protects against in vivo beta2-adrenoceptor subsensitivity induced by regular formoterol

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12 December 2020

Concomitant inhaled corticosteroid resensitises cardiac beta2-adrenoceptors in the presence of long-acting beta2-agonist therapy

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12 December 2020

Short-term cardiovascular effects of salmeterol

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12 December 2020

Budesonide and formoterol in a single inhaler improves asthma control compared with increasing the dose of corticosteroid in adults with mild-to-moderate asthma

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12 December 2020

Comparison of a beta 2-agonist, terbutaline, with an inhaled corticosteroid, budesonide, in newly detected asthma

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12 December 2020

Effect of intravenous prednisolone in asthmatics with diminished adrenergic responsiveness

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol

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12 December 2020

Regular inhaled salbutamol and airway responsiveness to allergen

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12 December 2020

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12 December 2020

Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma.

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12 December 2020

Revisiting interactions between hypoxaemia and beta2 agonists in asthma

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12 December 2020

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12 December 2020

An antiinflammatory effect of salmeterol, a long-acting beta(2) agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma

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12 December 2020

Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling

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12 December 2020

Regular vs as-needed inhaled salbutamol in asthma control

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12 December 2020

Subsensitivity of bronchodilator and systemic beta 2 adrenoceptor responses after regular twice daily treatment with eformoterol dry powder in asthmatic patients

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12 December 2020

An inhaled glucocorticoid does not prevent tolerance to the bronchoprotective effect of a long-acting inhaled beta 2-agonist

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12 December 2020

Decreased bronchodilating effect of salbutamol in relieving methacholine induced moderate to severe bronchoconstriction during high dose treatment with long acting beta2 agonists

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12 December 2020

Long-term effects of a long-acting beta 2-adrenoceptor agonist, salmeterol, on airway hyperresponsiveness in patients with mild asthma

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12 December 2020

Lack of subsensitivity to albuterol after treatment with salmeterol in patients with asthma

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12 December 2020

Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: a randomized controlled trial

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12 December 2020

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12 December 2020

Tolerance to the bronchoprotective effect of salmeterol 12 hours after starting twice daily treatment

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12 December 2020

Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol

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12 December 2020

Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids

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12 December 2020

Amino-terminal polymorphisms of the human beta 2-adrenergic receptor impart distinct agonist-promoted regulatory properties.

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12 December 2020

Regular inhaled beta-agonist treatment in bronchial asthma.

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

The effect of salmeterol on markers of airway inflammation following segmental allergen challenge

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12 December 2020

Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group.

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12 December 2020

Effect of inhaled fluticasone with and without salmeterol on airway inflammation in asthma

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12 December 2020

A comparison of salmeterol and formoterol in attenuating airway responses to short-acting β2-agonists

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12 December 2020

Cardiac effects of formoterol and salmeterol in patients suffering from COPD with preexisting cardiac arrhythmias and hypoxemia

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12 December 2020

The interaction between salmeterol and beta 2-adrenoceptor agonists with higher efficacy on guinea-pig trachea and human bronchus in vitro

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12 December 2020

Montelukast versus salmeterol in patients with asthma and exercise-induced bronchoconstriction. Montelukast/Salmeterol Exercise Study Group

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12 December 2020

Long-term cardiovascular safety of salmeterol powder pharmacotherapy in adolescent and adult patients with chronic persistent asthma: a randomized clinical trial

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12 December 2020

Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

1 reference

12 December 2020

Impact of genetic polymorphisms of the beta2-adrenergic receptor on albuterol bronchodilator pharmacodynamics.

1 reference

12 December 2020

The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma

1 reference

12 December 2020

A bolus of inhaled budesonide rapidly reverses airway subsensitivity and beta2-adrenoceptor down-regulation after regular inhaled formoterol.

1 reference

12 December 2020

Long-term circadian effects of salmeterol in asthmatic children treated with inhaled corticosteroids

1 reference

12 December 2020

The use of beta-agonists and the risk of death and near death from asthma

1 reference

12 December 2020

Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients

1 reference

12 December 2020

Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol

1 reference

12 December 2020

Addition of salmeterol versus doubling the dose of fluticasone propionate in patients with mild to moderate asthma

1 reference

12 December 2020

Add-on therapy with montelukast or formoterol in patients with the glycine-16 beta2-receptor genotype

1 reference

12 December 2020

Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol

1 reference

12 December 2020

In vivo effect of albuterol on methacholine-contracted bronchi in conjunction with salmeterol and formoterol

1 reference

12 December 2020

Salmeterol, formoterol, and salbutamol in the isolated guinea pig trachea: differences in maximum relaxant effect and potency but not in functional antagonism

1 reference

12 December 2020

Improved asthma control with budesonide/formoterol in a single inhaler, compared with budesonide alone

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12 December 2020

Potential masking effects of salmeterol on airway inflammation in asthma

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12 December 2020

Steroid-sparing effects of fluticasone propionate 100 microg and salmeterol 50 microg administered twice daily in a single product in patients previously controlled with fluticasone propionate 250 microg administered twice daily

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12 December 2020

A comparison of salmeterol with albuterol in the treatment of mild-to-moderate asthma

1 reference

12 December 2020

Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients

1 reference

12 December 2020

Effect of prednisolone and ketotifen on beta 2-adrenoceptors in asthmatic patients receiving beta 2-bronchodilators

1 reference

12 December 2020

Bronchodilator response to albuterol after regular formoterol and effects of acute corticosteroid administration

1 reference

12 December 2020

Effect of long-term salmeterol treatment on exercise-induced asthma

1 reference

12 December 2020

The addition of salmeterol to fluticasone propionate versus increasing the dose of fluticasone propionate in patients with persistent asthma. Salmeterol Study Group

1 reference

12 December 2020

Twelve month comparison of salmeterol and salbutamol as dry powder formulations in asthmatic patients. European Study Group

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12 December 2020

Effect of long-term treatment with salmeterol on asthma control: a double blind, randomised crossover study

1 reference

12 December 2020

Comparison of combination inhalers vs inhaled corticosteroids alone in moderate persistent asthma.

1 reference

12 December 2020

Combined salmeterol 50 microg and fluticasone propionate 250 microg in the diskus device for the treatment of asthma

1 reference

12 December 2020

Inhaled corticosteroids do not prevent the development of tolerance to the bronchoprotective effect of salmeterol

1 reference

12 December 2020

Low dose inhaled budesonide and formoterol in mild persistent asthma: the OPTIMA randomized trial

1 reference

12 December 2020

Agonist-Promoted High Affinity State of the β-Adrenergic Receptor in Human Neutrophils: Modulation by Corticosteroids*

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12 December 2020

Fluticasone propionate/salmeterol combination provides more effective asthma control than low-dose inhaled corticosteroid plus montelukast

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12 December 2020

Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: a randomized, double-blind, placebo-controlled trial

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12 December 2020

Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Allen & Hanburys Limited UK Study Group

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12 December 2020

Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis

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12 December 2020

Airway responsiveness after a single dose of salmeterol and during four months of treatment in children with asthma

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12 December 2020

Beta-adrenergic receptors in hamster smooth muscle cells are transcriptionally regulated by glucocorticoids

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12 December 2020

Salmeterol tachyphylaxis in steroid treated asthmatic subjects

1 reference

12 December 2020

Tolerance to the bronchoprotective effect of salmeterol in adolescents with exercise-induced asthma using concurrent inhaled glucocorticoid treatment.

1 reference

12 December 2020

Effect of salmeterol treatment on nitric oxide level in exhaled air and dose-response to terbutaline in children with mild asthma

1 reference

12 December 2020

Effect of eight weeks of treatment with salmeterol on bronchoalveolar lavage inflammatory indices in asthmatics

1 reference

12 December 2020

Salmeterol and conventional asthma therapy

1 reference

12 December 2020

Early intervention with budesonide in mild persistent asthma: a randomised, double-blind trial

1 reference

12 December 2020

Effect of combining salmeterol and fluticasone on the progression of airway remodeling

1 reference

12 December 2020

Enhanced synergy between fluticasone propionate and salmeterol inhaled from a single inhaler versus separate inhalers

1 reference

12 December 2020

Long- and short-acting beta2 adrenoceptor agonists: interactions in human contracted bronchi

1 reference

12 December 2020

Cardiovascular safety of salmeterol in COPD.

1 reference

12 December 2020

10.2165/00002018-200427040-00003

Identifiers

DOI

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PubMed ID

15003036

Dimensions Publication ID

9 August 2017

0 references

1 reference

PubMed ID

15003036