Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin (Q35683618)

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scientific article published on 27 October 2011

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English	Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin	scientific article published on 27 October 2011

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scholarly article

1 reference

Europe PubMed Central

9 August 2017

Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin (English)

1 reference

Europe PubMed Central

9 August 2017

0 references

metastatic breast cancer

1 reference

based on heuristic

inferred from title

author name string

Daniel Mendoza-Villanueva

1

1 reference

Europe PubMed Central

9 August 2017

Leo Zeef

2

1 reference

Europe PubMed Central

9 August 2017

Paul Shore

3

1 reference

Europe PubMed Central

9 August 2017

publication date

27 October 2011

1 reference

Europe PubMed Central

9 August 2017

Breast Cancer Research

1 reference

Europe PubMed Central

9 August 2017

13

1 reference

Europe PubMed Central

9 August 2017

5

1 reference

Europe PubMed Central

9 August 2017

R106

1 reference

Europe PubMed Central

9 August 2017

https://scigraph.springernature.com/pub.10.1186/bcr3048

0 references

Breast cancer metastasis to the bone: mechanisms of bone loss

1 reference

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12 July 2018

Tumor-supportive and osteoclastogenic changes induced by breast cancer-derived factors are reversed by inhibition of {gamma}-secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Advances in the biology of bone metastasis: how the skeleton affects tumor behavior

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Activin A and bone metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Sclerostin: current knowledge and future perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

1 reference

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12 July 2018

Osteoblasts suppress high bone turnover caused by osteolytic breast cancer in-vitro

1 reference

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1 reference

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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

1 reference

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1 reference

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12 July 2018

Breast cancer-derived Dickkopf1 inhibits osteoblast differentiation and osteoprotegerin expression: implication for breast cancer osteolytic bone metastases

1 reference

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12 July 2018

Osteocytes, mechanosensing and Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Biology of breast cancer bone metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

RUNX genes in development and cancer: regulation of viral gene expression and the discovery of RUNX family genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

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Skeletal metastases: decreasing tumor burden by targeting the bone microenvironment

1 reference

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12 July 2018

Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton

1 reference

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12 July 2018

Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

1 reference

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12 July 2018

Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Oct-1 counteracts autoinhibition of Runx2 DNA binding to form a novel Runx2/Oct-1 complex on the promoter of the mammary gland-specific gene beta-casein

1 reference

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Role of osteopontin in adhesion, migration, cell survival and bone remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

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An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction

1 reference

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AML1/Runx1 recruits calcineurin to regulate granulocyte macrophage colony-stimulating factor by Ets1 activation

1 reference

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12 July 2018

Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

12 July 2018

The osteoblast transcription factor Runx2 is expressed in mammary epithelial cells and mediates osteopontin expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3262219

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Statistical significance for genomewide studies

1 reference

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A multigenic program mediating breast cancer metastasis to bone

1 reference

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Structural and functional characterization of Runx1, CBF beta, and CBF beta-SMMHC.

1 reference

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1 reference

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Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta

1 reference

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NF-kappaB in breast cancer cells promotes osteolytic bone metastasis by inducing osteoclastogenesis via GM-CSF.

1 reference

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1 reference

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1 reference

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25 September 2018

Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones

1 reference

https://pubmed.ncbi.nlm.nih.gov/22032690

12 December 2020

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10.1186/BCR3048

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Europe PubMed Central

9 August 2017

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1 reference

Europe PubMed Central

9 August 2017

1 reference

Europe PubMed Central

9 August 2017

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