CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4. (Q35688370)

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scientific article published on September 2006

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English	CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4.	scientific article published on September 2006

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scholarly article

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29 December 2019

CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4 (English)

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29 December 2019

James P Hewitson

1

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29 December 2019

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Gavin R Jenkins

2

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29 December 2019

Paul A Hamblin

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29 December 2019

Adrian P Mountford

4

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29 December 2019

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1 September 2006

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29 December 2019

Journal of Immunology

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29 December 2019

177

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29 December 2019

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29 December 2019

3209-3217

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29 December 2019

Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways.

1 reference

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12 July 2018

Modulation of the host's immune response by schistosome larvae.

1 reference

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12 July 2018

Immunity induced by the radiation-attenuated schistosome vaccine

1 reference

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12 July 2018

Dendritic cells activated with products released by schistosome larvae drive Th2-type immune responses, which can be inhibited by manipulation of CD40 costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

CD154 signaling regulates the Th1 response to herpes simplex virus-1 and inflammation in infected corneas

1 reference

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12 July 2018

Schistosomes in the skin: a balance between immune priming and regulation

1 reference

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12 July 2018

CD40/CD154 interactions at the interface of tolerance and immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

Interleukin-12 p40 secretion by cutaneous CD11c+ and F4/80+ cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

The biological outcome of CD40 signaling is dependent on the duration of CD40 ligand expression: reciprocal regulation by interleukin (IL)-4 and IL-12.

1 reference

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12 July 2018

The immunobiology of schistosomiasis

1 reference

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12 July 2018

Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

The CD40/CD154 receptor/ligand dyad

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

Signaling via interleukin-4 receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

CD40-CD40 ligand interactions in vivo regulate migration of antigen-bearing dendritic cells from the skin to draining lymph nodes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

CD40 ligand is not essential for the development of cell-mediated immunity and resistance to Mycobacterium tuberculosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

The CD40-CD154 system in anti-infective host defense

1 reference

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12 July 2018

The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

High level IL-12 production by murine dendritic cells: upregulation via MHC class II and CD40 molecules and downregulation by IL-4 and IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

CD40-mediated stimulation contributes to lymphocyte proliferation, antibody production, eosinophilia, and mastocytosis during an in vivo type 2 response, but is not required for T cell IL-4 production.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

Activation of human dendritic cells through CD40 cross-linking.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

Monoclonal antibody to IFN-gamma modifies pulmonary inflammatory responses and abrogates immunity to Schistosoma mansoni in mice vaccinated with attenuated cercariae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

12 July 2018

Distinct in vivo dendritic cell activation by live versus killed Listeria monocytogenes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

25 September 2018

Loss of CD154 impairs the Th2 extrafollicular plasma cell response but not early T cell proliferation and interleukin-4 induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

25 September 2018

Disruption of CD40-CD40 ligand pathway inhibits the development of intestinal muscle hypercontractility and protective immunity in nematode infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

25 September 2018

TRANCE-RANK Costimulation is Required for IL-12 Production and the Initiation of a Th1-Type Response toLeishmania majorInfection in CD40L-Deficient Mice

1 reference

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25 September 2018

Tissue-level regulation of Th1 and Th2 primary and memory CD4 T cells in response to Listeria infection.

1 reference

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25 September 2018

A role for CD40-CD40 ligand interactions in the generation of type 1 cytokine responses in human leprosy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

25 September 2018

TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

25 September 2018

Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

25 September 2018

Co-administration of CD40 agonistic antibody and antigen fails to overcome the induction of oral tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1828121

23 October 2018

Accessory signaling by CD40 for T cell activation: induction of Th1 and Th2 cytokines and synergy with interleukin-12 for interferon-gamma production

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human dendritic cells following infection with Mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: Th2 response induction by dendritic cells: a role for CD40

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired Th2 development and increased mortality during Schistosoma mansoni infection in the absence of CD40/CD154 interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered T helper responses in CD40 and interleukin-12 deficient mice reveal a critical role for Th1 responses in eliminating the helminth parasite Taenia crassiceps

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Schistosoma mansoni: antigen-presenting cells emigrating from skin exposed to attenuated cercariae activate lymphoid cells and transfer protection in C57B1/6 mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 preferentially costimulates activation of CD4+ T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated expression of Th1 cytokines and nitric oxide synthase in the lungs of vaccinated mice after challenge infection with Schistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice deficient for the CD40 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T cells induce interleukin-12 production by monocytes via CD40-CD40 ligand interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of CD40 with purified soluble gp39 induces proinflammatory responses in human monocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40 ligand is required for protective cell-mediated immunity to Leishmania major

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In the absence of IL-12, the induction of Th1-mediated protective immunity by the attenuated schistosome vaccine is impaired, revealing an alternative pathway with Th2-type characteristics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An obligate role for T-cell receptor alphabeta+ T cells but not T-cell receptor gammadelta+ T cells, B cells, or CD40/CD40L interactions in a mouse model of atopic dermatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16920960

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.177.5.3209

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920960%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920960%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16920960%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

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