E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis (Q35689250)

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scientific article published on 5 December 2011

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English	E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis	scientific article published on 5 December 2011

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scholarly article

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17 January 2020

E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis (English)

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17 January 2020

Inositol acyltransferase with a predicted role in GPI anchor biosynthesis

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5 February 2019

Candida albicans

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based on heuristic

inferred from title

4

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17 January 2020

author name string

Nao-Aki Watanabe

1

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17 January 2020

Mamiko Miyazaki

2

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17 January 2020

Takaaki Horii

3

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17 January 2020

Kappei Tsukahara

5

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17 January 2020

Katsura Hata

6

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17 January 2020

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5 December 2011

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17 January 2020

Antimicrobial Agents and Chemotherapy

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17 January 2020

56

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17 January 2020

2

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17 January 2020

960-971

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17 January 2020

In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Efficacy of oral E1210, a new broad-spectrum antifungal with a novel mechanism of action, in murine models of candidiasis, aspergillosis, and fusariosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3264227

12 July 2018

Characterisation of Pga1, a putative Candida albicans cell wall protein necessary for proper adhesion and biofilm formation

1 reference

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12 July 2018

Therapy for fungal diseases: opportunities and priorities

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12 July 2018

Results from the ARTEMIS DISK Global Antifungal Surveillance Study, 1997 to 2007: a 10.5-year analysis of susceptibilities of Candida Species to fluconazole and voriconazole as determined by CLSI standardized disk diffusion.

1 reference

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12 July 2018

Forward genetics in Candida albicans that reveals the Arp2/3 complex is required for hyphal formation, but not endocytosis.

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In vitro activity of micafungin against planktonic and sessile Candida albicans isolates

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12 July 2018

Candida albicans cell wall proteins

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Aspergillus fumigatus forms biofilms with reduced antifungal drug susceptibility on bronchial epithelial cells

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In vitro survey of triazole cross-resistance among more than 700 clinical isolates of Aspergillus species

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Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans

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Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans

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Eap1p, an adhesin that mediates Candida albicans biofilm formation in vitro and in vivo.

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12 July 2018

Thematic review series: lipid posttranslational modifications. GPI anchoring of protein in yeast and mammalian cells, or: how we learned to stop worrying and love glycophospholipids.

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Trends in the epidemiology of invasive fungal infections.

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12 July 2018

Comprehensive analysis of glycosylphosphatidylinositol-anchored proteins in Candida albicans

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12 July 2018

Function of Candida albicans adhesin Hwp1 in biofilm formation.

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12 July 2018

Biosynthesis and function of GPI proteins in the yeast Saccharomyces cerevisiae

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12 July 2018

Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence

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International surveillance of Candida spp. and Aspergillus spp.: report from the SENTRY Antimicrobial Surveillance Program (2003).

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12 July 2018

Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum

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Candida biofilms: an update

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12 July 2018

Small-molecule inhibitors of the budded-to-hyphal-form transition in the pathogenic yeast Candida albicans

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12 July 2018

Development and characterization of an in vivo central venous catheter Candida albicans biofilm model.

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12 July 2018

Functional and structural diversity in the Als protein family of Candida albicans

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12 July 2018

Superoxide Dismutases inCandida albicans: Transcriptional Regulation and Functional Characterization of the Hyphal-inducedSOD5Gene

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12 July 2018

PIG-W Is Critical for Inositol Acylation but Not for Flipping of Glycosylphosphatidylinositol-Anchor

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12 July 2018

Sensitive Assay for Antifungal Activity of Glucan Synthase Inhibitors That Uses Germ Tube Formation in Candida albicans as an End Point

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12 July 2018

Inhibitors of glycosyl-phosphatidylinositol anchor biosynthesis

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12 July 2018

GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast

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12 July 2018

Candida albicans Mds3p, a conserved regulator of pH responses and virulence identified through insertional mutagenesis.

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12 July 2018

In vitro activity of caspofungin against Candida albicans biofilms.

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12 July 2018

Candida albicans Als1p: an adhesin that is a downstream effector of the EFG1 filamentation pathway.

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Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms

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12 July 2018

The ALS gene family of Candida albicans

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12 July 2018

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

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12 July 2018

Pig-n, a mammalian homologue of yeast Mcd4p, is involved in transferring phosphoethanolamine to the first mannose of the glycosylphosphatidylinositol

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The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

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Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

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The effects of antifungal agents on the morphogenetic transformation by Candida albicans in vitro

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Adherence of Candida albicans germ tubes to plastic: ultrastructural and molecular studies of fibrillar adhesins

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12 July 2018

Inositol acylation of a potential glycosyl phosphoinositol anchor precursor from yeast requires acyl coenzyme A

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25 September 2018

Complementary adhesin function in C. albicans biofilm formation

1 reference

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25 September 2018

In vitro effects of micafungin against Candida biofilms on polystyrene and central venous catheter sections

1 reference

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25 September 2018

Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions

1 reference

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25 September 2018

Deficiencies in the essential Smp3 mannosyltransferase block glycosylphosphatidylinositol assembly and lead to defects in growth and cell wall biogenesis in Candida albicans

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

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A conditionally lethal yeast mutant blocked at the first step in glycosyl phosphatidylinositol anchor synthesis

1 reference

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12 December 2020

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A rapid colorimetric assay for determination of leukocyte-mediated inhibition of mycelial growth of Candida albicans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22143530

12 December 2020

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Multiple-Triazole–Resistant Aspergillosis

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Changing pattern of candidaemia 2001-2006 and use of antifungal therapy at the University Hospital of Vienna, Austria

1 reference

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10.1128/AAC.00731-11

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17 January 2020

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17 January 2020

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17 January 2020

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