Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels (Q35694025)

9 August 2017

title

Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels (English)

1 reference

9 August 2017

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C Y Daniel Lee

1

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9 August 2017

Wayne Tse

series ordinal

2

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9 August 2017

Jonathan D Smith

series ordinal

3

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9 August 2017

Gary E Landreth

series ordinal

4

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9 August 2017

language of work or name

English

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publication date

30 November 2011

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Journal of Biological Chemistry

9 August 2017

published in

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9 August 2017

volume

287

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9 August 2017

issue

3

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9 August 2017

page(s)

2032-2044

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describes a project that uses

9 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3265883/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

12 July 2018

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12 July 2018

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12 July 2018

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

12 July 2018

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Isoform-specific binding of apolipoprotein E to beta-amyloid

12 July 2018

1 reference

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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

12 July 2018

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Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

12 July 2018

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Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

12 July 2018

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Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease.

12 July 2018

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Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid

12 July 2018

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Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice.

12 July 2018

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The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease.

25 September 2018

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Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265883

The absence of ABCA1 decreases soluble ApoE levels but does not diminish amyloid deposition in two murine models of Alzheimer disease.

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265883

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265883

Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265883

A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.

25 September 2018

1 reference

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High-yield isolation of murine microglia by mild trypsinization.

25 September 2018

1 reference

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Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway

25 September 2018

1 reference

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Statin therapy for Alzheimer's disease: will it work?

25 September 2018

1 reference

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Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide

25 September 2018

1 reference

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Two distal downstream enhancers direct expression of the human apolipoprotein E gene to astrocytes in the brain.

25 September 2018

1 reference

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A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1.

25 September 2018

1 reference

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Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid

25 September 2018

1 reference

12 December 2020

Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid

1 reference

12 December 2020

Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture

1 reference

12 December 2020

Alzheimer A beta neurotoxicity: promotion by antichymotrypsin, ApoE4; inhibition by A beta-related peptides

1 reference

12 December 2020

An apolipoprotein A-I mimetic works best in the presence of apolipoprotein A-I

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.295451

1 reference

9 August 2017

1 reference

9 August 2017

1 reference