Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond. (Q35696684)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15030506%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

review article

1 reference

title

Unravelling the genetic complexity of autoimmune thyroid disease: HLA, CTLA-4 and beyond (English)

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25 December 2019

1

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25 December 2019

author name string

S C L Gough

series ordinal

2

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25 December 2019

publication date

1 April 2004

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Clinical and Experimental Immunology

25 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15030506%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

136

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25 December 2019

issue

1

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25 December 2019

page(s)

1-10

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Clonal expansion versus functional clonal inactivation: a costimulatory signalling pathway determines the outcome of T cell antigen receptor occupancy

25 December 2019

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CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease

21 January 2018

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Clustering of autoimmune disease in parents of siblings from the Type 1 diabetes Warren repository

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Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease

25 September 2018

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Association of a rare thyroglobulin gene microsatellite variant with autoimmune thyroid disease

25 September 2018

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Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families

25 September 2018

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

25 September 2018

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25 September 2018

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CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

25 September 2018

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CTLA-4-Ig regulates tryptophan catabolism in vivo.

25 September 2018

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Inhibition of human T cell proliferation by CTLA-4 utilizes CD80 and requires CD25+ regulatory T cells.

25 September 2018

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25 September 2018

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Replication validity of genetic association studies

25 September 2018

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Up to date with human thyroglobulin.

25 September 2018

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Iodine and thyroid autoimmune disease in animal models

25 September 2018

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A physical map of the human genome

25 September 2018

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Evidence for a major role of heredity in Graves' disease: a population-based study of two Danish twin cohorts

25 September 2018

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Evidence for a Graves' disease susceptibility locus at chromosome Xp11 in a United Kingdom population

25 September 2018

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The genetics of Graves' disease

25 September 2018

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A native soluble form of CTLA-4

25 September 2018

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A population-based study of chronic autoimmune hypothyroidism in Danish twins.

25 September 2018

1 reference

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A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells

25 September 2018

1 reference

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The different approaches to the genetic analysis of autoimmune thyroid disease

25 September 2018

1 reference

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Association of the large multifunctional proteasome (LMP2) gene with Graves' disease is a result of linkage disequilibrium with the HLA haplotype DRB1*0304-DQB1*02-DQA1*0501.

25 September 2018

1 reference

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The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus.

25 September 2018

1 reference

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No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies.

25 September 2018

1 reference

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Effects of environmental synthetic chemicals on thyroid function.

25 September 2018

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CTLA-4 promoter variants in patients with Graves' disease and Hashimoto's thyroiditis

25 September 2018

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A second-generation screen of the human genome for susceptibility to insulin-dependent diabetes mellitus

25 September 2018

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Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.

25 September 2018

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The pathogenesis of Graves' disease

25 September 2018

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A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism.

25 September 2018

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Anti-thyroglobulin autoantibodies in autoimmune thyroid diseases: cross-reactive or pathogenic?

25 September 2018

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CTLA4 alanine-17 confers genetic susceptibility to Graves' disease and to type 1 diabetes mellitus.

25 September 2018

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The interaction of a type A retroviral particle and class II human leukocyte antigen susceptibility genes in the pathogenesis of Graves' disease.

25 September 2018

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25 September 2018

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The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

25 September 2018

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Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation

25 September 2018

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Association of HLA-DQA1*0501 with Graves' disease in English Caucasian men and women.

25 September 2018

1 reference

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CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

25 September 2018

1 reference

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Lack of an independent association between the human leukocyte antigen allele DQA1*0501 and Graves' disease.

25 September 2018

1 reference

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CTLA-4 can function as a negative regulator of T cell activation

25 September 2018

1 reference

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CTLA-4 gene polymorphism associated with Graves' disease in a Caucasian population.

25 September 2018

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Susceptibility and resistance alleles of human leukocyte antigen (HLA) DQA1 and HLA DQB1 are shared in endocrine autoimmune disease

25 September 2018

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25 September 2018

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The human thyroglobulin gene is over 300 kb long and contains introns of up to 64 kb

25 September 2018

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25 September 2018

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25 September 2018

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HLA antigens in Graves' disease

25 September 2018

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CTLA4 gene and Graves' disease: association of Graves' disease with the CTLA4 exon 1 and intron 1 polymorphisms, but not with the promoter polymorphism

25 September 2018

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25 September 2018

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Polymorphism of the CTLA-4 gene is associated with autoimmune hypothyroidism in the United Kingdom

25 September 2018

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25 September 2018

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Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese

25 September 2018

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Association of DRB1*04-DQB1*0301 haplotype and lack of association of two polymorphic sites at CTLA-4 gene with Hashimoto's thyroiditis in an Italian population

25 September 2018

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Limited genetic susceptibility to severe Graves' ophthalmopathy: no role for CTLA-4 but evidence for an environmental etiology

25 September 2018

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Genetic and physical mapping of a type 1 diabetes susceptibility gene (IDDM12) to a 100-kb phagemid artificial chromosome clone containing D2S72-CTLA4-D2S105 on chromosome 2q33

25 September 2018

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Cutting edge: a soluble form of CTLA-4 in patients with autoimmune thyroid disease

25 September 2018

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CTLA-4 and HLA gene susceptibility to thyroid-associated orbitopathy

25 September 2018

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The development of Graves' disease and the CTLA-4 gene on chromosome 2q33

25 September 2018

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No major role for the CTLA-4 gene in the association of autoimmune thyroid disease with IDDM

25 September 2018

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Codon 17 polymorphism of the cytotoxic T lymphocyte antigen 4 gene in Hashimoto's thyroiditis and Addison's disease

25 September 2018

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Serological evidence for the role of bacterial infections in the pathogenesis of thyroid diseases

25 September 2018

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HLA DQA1*0501 and DRB1*0301 antigens do not independently convey susceptibility to Graves' disease

21 January 2018

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Association of Graves' disease with an allele of the interleukin-1 receptor antagonist gene

21 January 2018

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12 December 2020

HLA class II gene polymorphism contributes little to Hashimoto's thyroiditis

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12 December 2020

HL-A Antigens as Markers for Disease Susceptibility and Autoimmunity in Graves' Disease

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The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA-DR3 positive AITD families

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Single-cell analysis of intrathyroidal lymphocytes shows differential cytokine expression in Hashimoto's and Graves' disease

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12 December 2020

Strong association between HLA-DQA1*0501 and Graves' disease in a male Caucasian population

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12 December 2020

HLA-A and -DRB4 genes in controlling the susceptibility to Hashimoto's thyroiditis

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12 December 2020

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease

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Dendritic cells and class II MHC expression on thyrocytes during the autoimmune thyroid disease of the BB rat

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12 December 2020

Association of the HLA-DRB1*0301 and HLA-DQA1*0501 alleles with Graves' disease in a population representing the gene contribution from several ethnic backgrounds

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Graves' disease. Predominance of the DRw3 antigen (author's transl)

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Genetic Factors in Autoimmune Thyroid Disease Analyzed by Restriction Fragment Length Polymorphisms of Candidate Genes*

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Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells

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No association of an interleukin 4 gene promoter polymorphism with Graves' disease in the United Kingdom

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The interleukin-1 receptor antagonist gene shows no allelic association with three autoimmune diseases

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12 December 2020

Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins

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The association of HLA with autoimmune thyroid disease in Newfoundland. The influence of HLA homozygosity in Graves' disease

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12 December 2020

HLA antigens and thyroid autoantibodies in patients with Graves' disease and their first degree relatives

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HLA-A, -B, -C and -DR antigens in patients with Graves' disease and their correlation with signs and clinical course

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12 December 2020

A polymorphism in the extracellular domain of the thyrotropin receptor is highly associated with autoimmune thyroid disease in females

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12 December 2020

Linkage disequilibrium between the human leukocyte antigen class II region of the major histocompatibility complex and Graves' disease: replication using a population case control and family-based study

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12 December 2020

Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases

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12 December 2020

HLA-DR and Hashimoto's thyroiditis

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12 December 2020

Lack of association between polymorphism of the thyrotropin receptor gene and Graves' disease in United Kingdom and Hong Kong Chinese patients: case control and family-based studies

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12 December 2020

Association of HLA antigen and restriction fragment length polymorphism of T cell receptor beta-chain gene with Graves' disease and Hashimoto's thyroiditis

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12 December 2020

HLA-DRB3 gene alleles in Caucasian patients with Graves' disease

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12 December 2020

Human histocompatibility leukocyte antigen-DQA1*0501 allele associated with genetic susceptibility to Graves' disease in a Caucasian population

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12 December 2020

Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: evidence for genetic heterogeneity and gene interactions

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12 December 2020

Cytokine Gene Expression in Autoimmune Thyroiditis in BioBreeding/Worcester Rats

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12 December 2020

A heterozygous deletion of the autoimmune regulator (AIRE1) gene, autoimmune thyroid disease, and type 1 diabetes: no evidence for association

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12 December 2020

HLA Associations with Hashimoto's thyroiditis

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12 December 2020

The spectrum of thyroid disease in a community: the Whickham survey

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12 December 2020

Life events, daily stresses and coping in patients with Graves' disease

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12 December 2020

Tumor necrosis factor beta gene polymorphisms in Graves' disease

1 reference

12 December 2020

10.1111/J.1365-2249.2004.02424.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15030506%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PMC publication ID

1808990

0 references

1 reference