The UPEC pore-forming toxin α-hemolysin triggers proteolysis of host proteins to disrupt cell adhesion, inflammatory, and survival pathways. (Q35697535)

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scientific article published on January 2012

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English	The UPEC pore-forming toxin α-hemolysin triggers proteolysis of host proteins to disrupt cell adhesion, inflammatory, and survival pathways.	scientific article published on January 2012

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scholarly article

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20 January 2020

The UPEC pore-forming toxin α-hemolysin triggers proteolysis of host proteins to disrupt cell adhesion, inflammatory, and survival pathways (English)

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20 January 2020

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Matthew A. Mulvey

2

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20 January 2020

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Bijaya K Dhakal

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20 January 2020

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1 January 2012

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20 January 2020

Cell Host & Microbe

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20 January 2020

11

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20 January 2020

1

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20 January 2020

58-69

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20 January 2020

Pore-forming toxins induce multiple cellular responses promoting survival.

1 reference

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27 July 2018

Global functional analyses of cellular responses to pore-forming toxins

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Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder

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Modulation of NF-κB signalling by microbial pathogens

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Listeria monocytogenes transiently alters mitochondrial dynamics during infection

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RAB-5- and RAB-11-dependent vesicle-trafficking pathways are required for plasma membrane repair after attack by bacterial pore-forming toxin.

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Attenuation of human neutrophil migration and function by uropathogenic bacteria.

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Role of MAPK p38 in the cellular responses to pore-forming toxins.

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Persistence of uropathogenic Escherichia coli in the face of multiple antibiotics

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Use of zebrafish to probe the divergent virulence potentials and toxin requirements of extraintestinal pathogenic Escherichia coli

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Relevance of fatty acid covalently bound to Escherichia coli alpha-hemolysin and membrane microdomains in the oligomerization process

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Bone morphogenetic protein 4 signaling regulates epithelial renewal in the urinary tract in response to uropathogenic infection

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27 July 2018

Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis

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Uropathogenic Escherichia coli invades host cells via an HDAC6-modulated microtubule-dependent pathway.

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Paxillin comes of age

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Caspases - an update

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27 July 2018

Hemolysin of uropathogenic Escherichia coli evokes extensive shedding of the uroepithelium and hemorrhage in bladder tissue within the first 24 hours after intraurethral inoculation of mice.

1 reference

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27 July 2018

Serine peptidases: classification, structure and function

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27 July 2018

Uropathogenic Escherichia coli dominantly suppress the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathway

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27 July 2018

Inactivation of host Akt/protein kinase B signaling by bacterial pore-forming toxins

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27 July 2018

Modulation of host innate immune response in the bladder by uropathogenic Escherichia coli

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27 July 2018

Integrin-mediated host cell invasion by type 1-piliated uropathogenic Escherichia coli

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The emerging role of serine proteases in apoptosis

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27 July 2018

Pore-forming toxins and cellular non-immune defenses (CNIDs).

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27 July 2018

Invasion of epithelial cells and proteolysis of cellular focal adhesion components by distinct types of Porphyromonas gingivalis fimbriae

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27 July 2018

Why Escherichia coli alpha-hemolysin induces calcium oscillations in mammalian cells--the pore is on its own.

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27 July 2018

Actin-gated intracellular growth and resurgence of uropathogenic Escherichia coli.

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27 July 2018

Novel three-dimensional organoid model for evaluation of the interaction of uropathogenic Escherichia coli with terminally differentiated human urothelial cells.

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27 July 2018

Escherichia coli mediated urinary tract infections: are there distinct uropathogenic E. coli (UPEC) pathotypes?

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Human mesotrypsin defies natural trypsin inhibitors: from passive resistance to active destruction

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27 July 2018

Covert operations of uropathogenic Escherichia coli within the urinary tract

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beta-catenin interacts with and inhibits NF-kappa B in human colon and breast cancer

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27 July 2018

In situ activation of caspases and serine proteases during apoptosis detected by affinity labeling their enzyme active centers with fluorochrome-tagged inhibitors

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27 July 2018

Molecular regulation of urothelial renewal and host defenses during infection with uropathogenic Escherichia coli

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27 July 2018

Cytotoxic necrotizing factor type 1 of uropathogenic Escherichia coli kills cultured human uroepithelial 5637 cells by an apoptotic mechanism

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27 July 2018

Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation

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Contribution of Escherichia coli alpha-hemolysin to bacterial virulence and to intraperitoneal alterations in peritonitis

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27 July 2018

Aerolysin induces G-protein activation and Ca2+ release from intracellular stores in human granulocytes

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27 July 2018

Association of RTX toxins with erythrocytes

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27 July 2018

Cytocidal effects of Escherichia coli hemolysin on human T lymphocytes

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Effect of Escherichia coli alpha-hemolysin on human peripheral leukocyte viability in vitro.

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Effect of Escherichia coli alpha-hemolysin on human peripheral leukocyte function in vitro

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Escherichia coli alpha-hemolysin: characteristics and probable role in pathogenicity

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Escherichia coli hemolysin may damage target cell membranes by generating transmembrane pores

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Role of alpha-hemolysin for the in vitro phagocytosis and intracellular killing of Escherichia coli.

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Virulence factors in Escherichia coli urinary tract infection

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Alpha-hemolysin contributes to the pathogenicity of piliated digalactoside-binding Escherichia coli in the kidney: efficacy of an alpha-hemolysin vaccine in preventing renal injury in the BALB/c mouse model of pyelonephritis

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Human-Restricted Bacterial Pathogens Block Shedding of Epithelial Cells by Stimulating Integrin Activation

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Histone modifications induced by a family of bacterial toxins

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Carbon monoxide prevents apoptosis induced by uropathogenic Escherichia coli toxins.

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Suppression of bladder epithelial cytokine responses by uropathogenic Escherichia coli

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Intracellular bacterial biofilm-like pods in urinary tract infections.

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Haemolysin contributes to virulence of extra-intestinal E. coli infections

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium-dependent conformation of E. coli alpha-haemolysin. Implications for the mechanism of membrane insertion and lysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22264513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/22264513

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.CHOM.2011.12.003

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22264513%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PMC publication ID

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Europe PubMed Central

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20 January 2020

PubMed publication ID

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Europe PubMed Central

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20 January 2020

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