CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer (Q35709153)

9 August 2017

title

CD146, an epithelial-mesenchymal transition inducer, is associated with triple-negative breast cancer (English)

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9 August 2017

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Qiqun Zeng

1

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9 August 2017

Weidong Li

2

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9 August 2017

Di Lu

3

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9 August 2017

Zhenzhen Wu

4

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9 August 2017

Hongxia Duan

5

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9 August 2017

Yongting Luo

6

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9 August 2017

Jing Feng

7

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9 August 2017

Dongling Yang

8

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9 August 2017

Li Fu

9

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9 August 2017

Xiyun Yan

10

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9 August 2017

language of work or name

English

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publication date

30 December 2011

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9 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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9 August 2017

volume

109

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9 August 2017

issue

4

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9 August 2017

page(s)

1127-1132

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Recognition of CD146 as an ERM-binding protein offers novel mechanisms for melanoma cell migration.

9 August 2017

cites work

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mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

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12 July 2018

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Epithelial-mesenchymal transitions in development and disease

12 July 2018

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Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization

12 July 2018

1 reference

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Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer

12 July 2018

1 reference

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Circulating tumor cells (CTCs): detection methods and their clinical relevance in breast cancer

12 July 2018

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Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers

12 July 2018

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Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma

12 July 2018

1 reference

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EMT, the cytoskeleton, and cancer cell invasion

12 July 2018

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CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

The epithelial-mesenchymal transition generates cells with properties of stem cells

12 July 2018

1 reference

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Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin

12 July 2018

1 reference

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Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro

12 July 2018

1 reference

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Anti-CD146 monoclonal antibody AA98 inhibits angiogenesis via suppression of nuclear factor-kappaB activation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition.

12 July 2018

1 reference

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M-CAM expression as marker of poor prognosis in epithelial ovarian cancer

12 July 2018

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Epithelial-mesenchymal transitions: twist in development and metastasis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

Isolation and characterization of the major form of human MUC18 cDNA gene and correlation of MUC18 over-expression in prostate cancer cell lines and tissues with malignant progression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

Rho GTPases and cell migration

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

Expression of a human cell adhesion molecule, MUC18, in prostate cancer cell lines and tissues

12 July 2018

1 reference

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Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanism

12 July 2018

1 reference

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A causal role for E-cadherin in the transition from adenoma to carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

Pre-eclampsia is associated with the failure of melanoma cell adhesion molecule (MCAM/CD146) expression by intermediate trophoblast

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268312

A novel anti-CD146 monoclonal antibody, AA98, inhibits angiogenesis and tumor growth

25 September 2018

1 reference

12 December 2020

Knockdown of CD146 reduces the migration and proliferation of human endothelial cells

1 reference

12 December 2020

Blockade of adhesion molecule CD146 causes pregnancy failure in mice

1 reference

12 December 2020

Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1111053108

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9 August 2017

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9 August 2017

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