p47 GTPases: regulators of immunity to intracellular pathogens (Q35709631)

9 August 2017

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title

p47 GTPases: regulators of immunity to intracellular pathogens (English)

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9 August 2017

3

Alan Sher

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9 August 2017

Gregory A Taylor

1

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PubMed ID

15040583

9 August 2017

Carl G Feng

series ordinal

2

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9 August 2017

1 February 2004

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Nature Reviews Immunology

9 August 2017

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9 August 2017

4

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9 August 2017

100-109

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9 August 2017

2

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https://scigraph.springernature.com/pub.10.1038/nri1270

9 August 2017

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cites work

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Divergent role for TNF-alpha in IFN-gamma-induced killing of Toxoplasma gondii and Salmonella typhimurium contributes to selective susceptibility of patients with partial IFN-gamma receptor 1 deficiency.

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Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae

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Multiple defects of immune cell function in mice with disrupted interferon-gamma genes

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Immune response in mice that lack the interferon-gamma receptor

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Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration

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Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase

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Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii

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Identification of nitric oxide synthase as a protective locus against tuberculosis

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Host resistance to intracellular infection: mutation of natural resistance-associated macrophage protein 1 (Nramp1) impairs phagosomal acidification

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Genomic structure, promoter sequence, and induction of expression of the mouse Nramp1 gene in macrophages.

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Oxygen-dependent anti-Salmonella activity of macrophages

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Chronic effects of γ-interferon on quinolinic acid and indoleamine-2,3-dioxygenase in brain of C57BL6 mice

31 March 2020

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Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP

31 March 2020

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Nucleotide-binding characteristics of human guanylate-binding protein 1 (hGBP1) and identification of the third GTP-binding motif

31 March 2020

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Murine GBP-5, a new member of the murine guanylate-binding protein family, is coordinately regulated with other GBPs in vivo and in vitro

31 March 2020

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GTPase properties of the interferon-induced human guanylate-binding protein 2

31 March 2020

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Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virus

31 March 2020

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The interferon (IFN)-induced GTPase, mGBP-2. Role in IFN-gamma-induced murine fibroblast proliferation

31 March 2020

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Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins

31 March 2020

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The antiviral dynamin family member, MxA, tubulates lipids and localizes to the smooth endoplasmic reticulum

31 March 2020

1 reference

Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope

31 March 2020

1 reference

Inhibition of coxsackievirus B4 replication in stably transfected cells expressing human MxA protein

31 March 2020

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Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

31 March 2020

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Dynamin undergoes a GTP-dependent conformational change causing vesiculation.

31 March 2020

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Nucleotide-dependent conformational changes in dynamin: evidence for a mechanochemical molecular spring

31 March 2020

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Interferon-induced mx proteins: dynamin-like GTPases with antiviral activity

31 March 2020

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Identification of a novel GTPase, the inducibly expressed GTPase, that accumulates in response to interferon gamma

31 March 2020

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The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding

31 March 2020

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Identification of an endotoxin and IFN-inducible cDNA: possible identification of a novel protein family.

31 March 2020

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Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein

31 March 2020

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The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments

31 March 2020

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The IFN-inducible Golgi- and endoplasmic reticulum- associated 47-kDa GTPase IIGP is transiently expressed during listeriosis

31 March 2020

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Pathogen-specific loss of host resistance in mice lacking the IFN-gamma-inducible gene IGTP

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IIGP1, an Interferon-γ-inducible 47-kDa GTPase of the Mouse, Showing Cooperative Enzymatic Activity and GTP-dependent Multimerization

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Interactions between Toxoplasma gondii and its mammalian host cells

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Phagosome acidification blocked by intracellular Toxoplasma gondii

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The interaction between Toxoplasma gondii and mammalian cells. II. The absence of lysosomal fusion with phagocytic vacuoles containing living parasites

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Inactivation of LRG-47 and IRG-47 reveals a family of interferon gamma-inducible genes with essential, pathogen-specific roles in resistance to infection

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Gamma interferon-induced inhibition of Toxoplasma gondii in astrocytes is mediated by IGTP.

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Evasion of innate immunity by parasitic protozoa

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Absence of interferon-gamma-inducible gene IGTP does not significantly alter the development of chagasic cardiomyopathy in mice infected with Trypanosoma cruzi (Brazil strain).

31 March 2020

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Interactions of Listeria monocytogenes with mammalian cells during entry and actin-based movement: bacterial factors, cellular ligands and signaling

31 March 2020

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Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes

31 March 2020

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Immune Control of Tuberculosis by IFN-γ-Inducible LRG-47

31 March 2020

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Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia.

31 March 2020

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Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.

31 March 2020

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Site-restricted persistent cytomegalovirus infection after selective long-term depletion of CD4+ T lymphocytes.

31 March 2020

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The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells

31 March 2020

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Phagocytosed live Listeria monocytogenes influences Rab5-regulated in vitro phagosome-endosome fusion.

31 March 2020

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Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes.

31 March 2020

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Interferon-gamma selectively induces Rab5a synthesis and processing in mononuclear cells

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Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages

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GTPases: multifunctional molecular switches regulating vesicular traffic

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GTP-binding domain: three consensus sequence elements with distinct spacing

31 March 2020

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Mx proteins: mediators of innate resistance to RNA viruses.

31 March 2020

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7 January 2021

Human MxA protein confers resistance to Semliki Forest virus and inhibits the amplification of a Semliki Forest virus-based replicon in the absence of viral structural proteins

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7 January 2021

Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infections

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7 January 2021

The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections.

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7 January 2021

Restoration of cytomegalovirus antigen presentation by gamma interferon combats viral escape.

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7 January 2021

Identifiers

DOI

10.1038/NRI1270

1 reference

PubMed ID

15040583

Dimensions Publication ID

9 August 2017

0 references

1 reference

PubMed ID

15040583