Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart. (Q35710032)

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scientific article published on 7 December 2011

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English	Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart.	scientific article published on 7 December 2011

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18 January 2020

Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart (English)

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18 January 2020

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18 January 2020

Sagartirtha Sarkar

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18 January 2020

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Saiful Anam Mir

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18 January 2020

Arunachal Chatterjee

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18 January 2020

Kanchan Pathak

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18 January 2020

Sushil K Mahata

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18 January 2020

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7 December 2011

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18 January 2020

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18 January 2020

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18 January 2020

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18 January 2020

2666-2677

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18 January 2020

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Analysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophy

1 reference

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12 July 2018

Can the protective actions of JAK-STAT in the heart be exploited therapeutically? Parsing the regulation of interleukin-6-type cytokine signaling

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12 July 2018

Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis

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Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

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Role of the JAK-STAT pathway in myocardial injury

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Prostaglandin E2 activates Stat3 in neonatal rat ventricular cardiomyocytes: A role in cardiac hypertrophy

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12 July 2018

Hypoxia/re-oxygenation-induced, redox-dependent activation of STAT1 (signal transducer and activator of transcription 1) confers resistance to apoptotic cell death via hsp70 induction.

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Hypertensive end-organ damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction

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12 July 2018

Constitutively activated Stat3 protects fibroblasts from serum withdrawal and UV-induced apoptosis and antagonizes the proapoptotic effects of activated Stat1

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12 July 2018

The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vivo

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Myocardial fibrosis associated with aldosterone or angiotensin II administration: attenuation by calcium channel blockade.

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Angiotensin II and myocyte growth: role of fibroblasts

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Mechanical stretch activates the JAK/STAT pathway in rat cardiomyocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22157761

12 December 2020

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inferred from PubMed ID database lookup

Myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure

1 reference

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12 December 2020

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12 December 2020

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inferred from PubMed ID database lookup

Upregulation of lysyl oxidase and MMPs during cardiac remodeling in human dilated cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/22157761

12 December 2020

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inferred from PubMed ID database lookup

Parthenolide inhibits STAT3 signaling and attenuates angiotensin II-induced left ventricular hypertrophy via modulation of fibroblast activity

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemia-induced STAT-1 Expression and Activation Play a Critical Role in Cardiomyocyte Apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22157761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Interleukin-6 family of cytokines mediate angiotensin II-induced cardiac hypertrophy in rodent cardiomyocytes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of myocytes in myocardial collagen production

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Emerging role of the JAK-STAT pathway as a mechanism of protection against ischemia/reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/22157761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in Janus kinase (JAK)-signal transducers and activators of transcription (STAT) signaling in patients with end-stage dilated cardiomyopathy

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Cardiac hypertrophy in spontaneously hypertensive rats

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased collagen synthesis and decreased collagen degradation in right ventricular hypertrophy induced by pressure overload

1 reference

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12 December 2020

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Arteriolar wall thickening, capillary rarefaction and interstitial fibrosis in the heart of rats with renal failure:the effects of ramipril, nifedipine and moxonidine

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of gp130 transduces hypertrophic signals via STAT3 in cardiac myocytes

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress activated protein kinase p38 is involved in IL-6 induced transcriptional activation of STAT3

1 reference

https://pubmed.ncbi.nlm.nih.gov/22157761

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1074/JBC.M111.246173

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18 January 2020

PMC publication ID

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Europe PubMed Central

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18 January 2020

PubMed publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22157761%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

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