Therapeutic effects of coenzyme Q10 in neurodegenerative diseases (Q35718544)

9 August 2017

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title

Therapeutic effects of coenzyme Q10 in neurodegenerative diseases (English)

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9 August 2017

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1

M Flint Beal

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9 August 2017

language of work or name

English

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publication date

1 January 2004

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9 August 2017

published in

Methods in Enzymology

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9 August 2017

volume

382

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9 August 2017

page(s)

473-487

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Regulation of ubiquinone metabolism

9 August 2017

cites work

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Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

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7 January 2021

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7 January 2021

Kinetic study of free-radical-scavenging action of biological hydroquinones (reduced forms of ubiquinone, vitamin K and tocopherol quinone) in solution

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7 January 2021

Comparative study on dynamics of antioxidative action of alpha-tocopheryl hydroquinone, ubiquinol, and alpha-tocopherol against lipid peroxidation

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7 January 2021

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Dietary cosupplementation with vitamin E and coenzyme Q(10) inhibits atherosclerosis in apolipoprotein E gene knockout mice

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7 January 2021

Coenzyme Q10 enrichment decreases oxidative DNA damage in human lymphocytes

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7 January 2021

Coenzyme Q is an obligatory cofactor for uncoupling protein function

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7 January 2021

Uncoupling proteins 2 and 3 are highly active H(+) transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)

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7 January 2021

The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP

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7 January 2021

Three classes of ubiquinone analogs regulate the mitochondrial permeability transition pore through a common site

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7 January 2021

A Ubiquinone-binding Site Regulates the Mitochondrial Permeability Transition Pore

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7 January 2021

Decreased ubiquinone levels in tissues of rats deficient in selenium

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7 January 2021

Selenium deficiency and decreased coenzyme Q levels

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7 January 2021

The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress

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7 January 2021

Ubiquinone is reduced by lipoamide dehydrogenase and this reaction is potently stimulated by zinc

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7 January 2021

Reduction of ubiquinone by lipoamide dehydrogenase

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7 January 2021

The role of DT-diaphorase in the maintenance of the reduced antioxidant form of coenzyme Q in membrane systems

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7 January 2021

Effect of coenzyme Q10 supplementation on mitochondrial function after myocardial ischemia reperfusion

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7 January 2021

Effect of coenzyme Q(10) on biochemical and morphological changes in experimental ischemia in the rat brain.

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7 January 2021

Ubiquinone protects cultured neurons against spontaneous and excitotoxin-induced degeneration

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7 January 2021

Coenzyme Q10 and nicotinamide block striatal lesions produced by the mitochondrial toxin malonate

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7 January 2021

Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases

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7 January 2021

Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10.

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7 January 2021

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

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7 January 2021

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

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7 January 2021

Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

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7 January 2021

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

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7 January 2021

Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects

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7 January 2021

Assessment of coenzyme Q10 tolerability in Huntington's disease

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7 January 2021

Spinocerebellar ataxias due to mitochondrial defects

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7 January 2021

Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia

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7 January 2021

Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis

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7 January 2021

Physical evidence that yeast frataxin is an iron storage protein

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7 January 2021

Antioxidant enzymes in blood of patients with Friedreich's ataxia.

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7 January 2021

Oxidative stress in patients with Friedreich ataxia.

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7 January 2021

Glutathione in blood of patients with Friedreich's ataxia.

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7 January 2021

Effect of idebenone on cardiomyopathy in Friedreich's ataxia: a preliminary study

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7 January 2021

Idebenone and reduced cardiac hypertrophy in Friedreich's ataxia

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7 January 2021

Antioxidant treatment improves in vivo cardiac and skeletal muscle bioenergetics in patients with Friedreich's ataxia

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7 January 2021

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

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7 January 2021

10.1016/S0076-6879(04)82026-3

Identifiers

DOI

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9 August 2017

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